What is the most effective way that you've found that can regulate the hormones behind the fight or flight response that leads to high blood pressure?

Mind-Body Connection. High blood pressure is caused by a number of factors: genetics, diet, stress, condition of arteries, underlying metabolic syndrome, etc. Getting to the root cause is key. Then treating with things like meditation/deep breathing, low carb/paleo diet, exercise, and vitamins/supplements may be helpful. And, dental disease/infection is a leading cause of cardiovascular disease- so fix that issue.