B19 is usually benign, but can cause fetal anemia
, non-immune fetal hydrops
- fluid in at least 2 areas: under the skin, in the abdomen, in the sacs around the lungs or heart
or in the placenta
Fetal demise may occur any time. Pregnant women exposed to 5th Disease need Parvovirus-specific IgG & IgM titers drawn a week apart &, if infected, referral to a fetal-maternal specialist.