7 doctors weighed in:

Does genetic play a role hearing loss susceptibility to aminoglycosides in children or adults?

7 doctors weighed in
Dr. Michael Olds
ENT - Head & Neck Surgery
4 doctors agree

In brief: Genetic hearing loss

Yes, a genetic mutation in mitochondrial RNA has been shown to predispose individuals to hearing and balance problems when they receive amino glycoside antibiotics.
This can happen even at low doses typically acknowledged to minimize the risk of toxicity. At high doses, however, amino glycosides can exhibit toxicity in the ear even in individuals without this mutation.

In brief: Genetic hearing loss

Yes, a genetic mutation in mitochondrial RNA has been shown to predispose individuals to hearing and balance problems when they receive amino glycoside antibiotics.
This can happen even at low doses typically acknowledged to minimize the risk of toxicity. At high doses, however, amino glycosides can exhibit toxicity in the ear even in individuals without this mutation.
Dr. Michael Olds
Dr. Michael Olds
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Dr. Gutti Rao
Internal Medicine - Hospital-based practice
1 doctor agrees

In brief: Yes

Mitochondrial genes have been identified which are thro maternal transmission responsible for aminoglycoside induced hearing loss.
South africans apparently are more prone for aminoglycoside hearing loss.

In brief: Yes

Mitochondrial genes have been identified which are thro maternal transmission responsible for aminoglycoside induced hearing loss.
South africans apparently are more prone for aminoglycoside hearing loss.
Dr. Gutti Rao
Dr. Gutti Rao
Thank
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