Is there any drugs interactions between norethisterone, metformin hcl& orlistat that may be harmful for me and how should I separate each dose safely?

Pharmacist. You should sit down with your pharmacist to discuss your medications. You can use a drug interaction checker whenever you have questions about drug-drug interactions or drug - food interactions. Here is 1 option (Drugs.Com): https://www.drugs.com/drug_interactions.php Your pharmacist is also a good source of info. Take care.