5 doctors weighed in:

Would pristiq (desvenlafaxine) and strattera be an effective combo for major depressive disorder and adult adhd? Stimulants have helped but too many side effects.

5 doctors weighed in
Dr. TRUC DAO
Psychiatry
2 doctors agree

In brief: Pristiq (desvenlafaxine) Strattera

Depression can cause long term fatigue, lack of energy at times difficult to improve till a stimulant is added.
Strattera (atomoxetine) is a weak stimulant but can help improve energy, if not Ritalin or Adderall can be added, if the patient does not have a cardiac problem.

In brief: Pristiq (desvenlafaxine) Strattera

Depression can cause long term fatigue, lack of energy at times difficult to improve till a stimulant is added.
Strattera (atomoxetine) is a weak stimulant but can help improve energy, if not Ritalin or Adderall can be added, if the patient does not have a cardiac problem.
Thank
Dr. Alan Ali
Psychiatry

In brief: Pristiq/Strattera

Safe, if Strattera is taken in morning & Pristiq (desvenlafaxine) at night.
Review with your doctor.

In brief: Pristiq/Strattera

Safe, if Strattera is taken in morning & Pristiq (desvenlafaxine) at night.
Review with your doctor.
Thank
Dr. Charles Kaegi
Psychiatry

In brief: Not a rational combo

Both Pristiq (desvenlafaxine) and strattera have nri.
Increased risk of adverse side effects. Would be better to add ssri to strattera. For adhd, Guanfacine may be effective.

In brief: Not a rational combo

Both Pristiq (desvenlafaxine) and strattera have nri.
Increased risk of adverse side effects. Would be better to add ssri to strattera. For adhd, Guanfacine may be effective.
Thank
1 comment
Dr. Donald Jacobson
I have a number of. Patients on this combo and it is working well. Strattera does not have much activity in the Limbic system . It's activity is in frontal lobe area where as Pristiq is much more active in the the Limbic system. I don't understand what you mean by irrational combination.
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