Have lung nodules and now it is amazingly painful to talk. Relevant? I don't mean throat things but my chest hurts when I talk.

Lung nodules. This requires medical attention. Call your doctor for an appointment.
Could be. Pain in the chest especially on deep breathing or on coughing implies that there is inflammation going on in and around the lungs. So it requires further investigation with repeat tests which may show changes which may indicate the need for further treatment or other interventions. You should let your doctor know about this development.