When diagnosing epstein barr virus & mono, are they two different blood tests taken when determining the proper diagnoses?

Mono syndromes. 80% of mono is thought due to EB virus and various screening tests can point to that diagnosis.A simple CBC can show a predominance of "monocytes" among the white cells.A screening monospot can be positive. To be sure it is an acute EB virus related infection specific EB virus antibodies can be ordered that differentiate EB from a half dozen other possibilities.It is seldom necessary for treatm.
See below. When you suspect mononucleosis you initially order a mono spot test. If this is negative you would order an ebv antibody panel. If this has a negative vca igm antibody you would check CMV and toxoplasmosis antibody and possibly an HIV viral load.