Why does kidney disease cause anemia? Epo?

Anemia in CKD. Chronic kidney disease (ckd) anemia is caused by the diseased kidneys not being able to make the hormone, erythropoietin (e). E stimulates the bone marrow to make new red blood cells. Epogen (epoetin alfa) is a man made drug that replicates e's affects on the bone marrow and is given to both CKD and dialysis patients to treat their anemia.
Anemia CKD. The production of hemoglobin in our bone marrow requires erythropoietin (EPO). More than 90 % of EPO production comes from healthy kidneys. As kidney health declines, EPO production declines. Thus hemoglobin production slows and does not keep pace with natural red blood cell cycling. Anemia results.