Variable reactions. Brown recluse spider's bite can cause no reaction, a mild reaction, an immediate or a delayed reaction. With a significant reaction a which blister appears after bit. The surrounding skin becomes hard, swollen & can be red, white & blue. A deep lesion can develop which can eat through fat and muscle. Other symptoms can include nausea, vomiting, fever, chills, generalized muscle and joint pains,
Brown recluse. Victims may experience these symptoms:severe pain at bite site after about four hours, severe itching, nausea, vomiting, fever, and myalgias (muscle pain). Sever symptoms include: blistering (common), necrosis (death) of skin and subcutaneous fat (less common), and severe destructive necrotic lesions with deep wide borders (rare).