Related Questions

Why is there an interaction between Coumadin and bactrim (sulfamethoxazole and trimethoprim)?

Increases free drug. Much of Coumadin is bound to protein. Many drugs, including bactrim, (sulfamethoxazole and trimethoprim) dislodge it from protein and increase the free (active) drug in the circulation. This usually results in a sharp spike in the inr and can lead to bleeding. If you must take batrim, you may need to skip a dose or two of coumadin. Discuss with your doctor. Read more...

Is there a negative interaction between bactrim (sulfamethoxazole and trimethoprim) ds and coumadin?

Yes. Bactrim (sulfamethoxazole and trimethoprim) ds increases effects of Coumadin by decreasing metabolism, by plasma protein binding competiton, and through hepatic enzyme cyp2c9/10 metabolism. Significant interaction possible.Monitor closely. Use alternatives if available. Read more...

My doctor gave me Bactrim (sulfamethoxazole and trimethoprim) when u got some bumps on my legs before, is there a substitute over-the-counter.

No. Bactrim (sulfamethoxazole and trimethoprim) is a prescription antibiotic that does not have an over the counter equivalent. If you have another issue that you feel may be infectious as was apparently treated in the past with bactrim, (sulfamethoxazole and trimethoprim) then you should see the dr. Best wishes. Read more...