3 doctors weighed in:

I read that endometriosis can cause infertility through a substance called prostaglandin. What is this and is it true?

3 doctors weighed in
Dr. Frank Yelian
Obstetrics & Gynecology
1 doctor agrees

In brief: Possible

It is true that endometriosis causes infertility.
However, the specific mechanism is not very clear. We believe that endometriosis may cause pelvic adhesion, affect the tubal function, decrease ovarian reserve, and reduce embryo implantation. There are several factors may be involved including prostaglandin, cytokine, such as tnfa.

In brief: Possible

It is true that endometriosis causes infertility.
However, the specific mechanism is not very clear. We believe that endometriosis may cause pelvic adhesion, affect the tubal function, decrease ovarian reserve, and reduce embryo implantation. There are several factors may be involved including prostaglandin, cytokine, such as tnfa.
Dr. Frank Yelian
Dr. Frank Yelian
Thank
Dr. Sheila Goodman
Obstetrics & Gynecology

In brief: Probably

Prostaglandin (pg) is a chemical produced in the body which can cause symptoms of pain, fever, headache, nausea, vomiting and diarrhea.
Some studies have shown that endometriosis increases the pg levels in the pelvis, which decreases the normal movement of the tubes around ovulation. This movement helps the egg and the sperm to move together and the fertilized egg to get to the uterus.

In brief: Probably

Prostaglandin (pg) is a chemical produced in the body which can cause symptoms of pain, fever, headache, nausea, vomiting and diarrhea.
Some studies have shown that endometriosis increases the pg levels in the pelvis, which decreases the normal movement of the tubes around ovulation. This movement helps the egg and the sperm to move together and the fertilized egg to get to the uterus.
Dr. Sheila Goodman
Dr. Sheila Goodman
Thank
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