4 doctors weighed in:
Would neurofibromatosis type 1 disqualify me from donating sperm to a sperm bank?
4 doctors weighed in

Dr. Scott McLean
Clinical Genetics
1 doctor agrees
In brief: Probably
As you know, neurofibromatosis type 1 (nf1) can affect some people mildly, but in others it can cause serious birth defects.
The chance that a sperm donor might pass the nf1 mutation to his biological child is 50% for each pregnancy. This would probably be considered an excessively high risk, so i suspect that sperm (and egg) donors with confirmed nf1 would not be invited to donate.

In brief: Probably
As you know, neurofibromatosis type 1 (nf1) can affect some people mildly, but in others it can cause serious birth defects.
The chance that a sperm donor might pass the nf1 mutation to his biological child is 50% for each pregnancy. This would probably be considered an excessively high risk, so i suspect that sperm (and egg) donors with confirmed nf1 would not be invited to donate.
Dr. Scott McLean
Dr. Scott McLean
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Dr. Gerald Mandell
Nuclear Medicine
In brief: Probably
Therefore 1 in 1500 are new cases.
Neurofibromatosis type 1 is considered to have an autosomal dominant pattern of inheritance. People with this condition are born with one mutated copy of the NF1 gene in each cell. In about half of cases, the altered gene is inherited from an affected parent. Estimated incidence of NF1 is 1 in 3000. Approximately half of affected individuals represent first cases in the family as a result of a new genetic event or mutation.

In brief: Probably
Therefore 1 in 1500 are new cases.
Neurofibromatosis type 1 is considered to have an autosomal dominant pattern of inheritance. People with this condition are born with one mutated copy of the NF1 gene in each cell. In about half of cases, the altered gene is inherited from an affected parent. Estimated incidence of NF1 is 1 in 3000. Approximately half of affected individuals represent first cases in the family as a result of a new genetic event or mutation.
Dr. Gerald Mandell
Dr. Gerald Mandell
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In brief: Yes
You will be disqualified as a sperm donor, during screening process.
Sperm bank will not accept people with any genetic disorders. Nf-1 is a genetic disorder involving chromosome 17, formerly known as ' von recklinghausen disease '.

In brief: Yes
You will be disqualified as a sperm donor, during screening process.
Sperm bank will not accept people with any genetic disorders. Nf-1 is a genetic disorder involving chromosome 17, formerly known as ' von recklinghausen disease '.
Dr. Addagada Rao
Dr. Addagada Rao
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