What is the significance of ca-125?

Ovarian Cancer. It is a tumor marker for ovarian, endometrium, fallopian tube, lung, breast and gastrointestinal tract cancers. It is commonly used to follow ovarian cancer in response to therapeutic treatments and can be positive in nearly 80% of cases. It is not specific to cancer, however, and can be elevated in benign abdominal problems too such as endometriosis.
Of ?? signifigance. Ca 125 may be produced by any gynecologic cancer(overy, uterus, ect) but it isn't always be true. It can also be produced by inflammatory diseases in the body(appendicitis, for example) it may also be used to follow a cancer pts progress if it was abnormal before starting treatment.