How long after discontinuing pristiq (desvenlafaxine) can I lose weight and how long will it take to lose the weight when stoppingnthe anti depressant?

Probably 2 weeks. Pristiq (desvenlafaxine) not usually associated with much wt gain. Assuming no other cause of wt gain, should be able to lose wt on Pristiq (desvenlafaxine) with right amount of exercise and calorie reduction.