2 doctors weighed in:

Is loratadine less severe than zyrtec (cetirizine)?

2 doctors weighed in
Dr. Neil Liebowitz
Psychiatry
1 doctor agrees

In brief: Loratadine is weaker

When loradine (claritin) was studied the manufacturer selected the lowest dose that gave a response better than placebo but didn't have more side effects than placebo.
This caused it to be a fairly weakly effective med. As it wasn't studied at higher dose i can't speak to safety of higher doses. Personally, i find zyrtec (cetirizine) to be much more effective but may be more sedating.

In brief: Loratadine is weaker

When loradine (claritin) was studied the manufacturer selected the lowest dose that gave a response better than placebo but didn't have more side effects than placebo.
This caused it to be a fairly weakly effective med. As it wasn't studied at higher dose i can't speak to safety of higher doses. Personally, i find zyrtec (cetirizine) to be much more effective but may be more sedating.
Dr. Neil Liebowitz
Dr. Neil Liebowitz
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