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Doctor insights on: Zyrtec Vs Benadryl For Dogs

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Dr. Andrew Murphy Dr. Murphy
Internal Medicine - Allergy & Immunology
25 years in practice
Pennsylvania State University College of Medicine
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Is it okay to take zyrtec with benadryl (diphenhydramine)?

Is it okay to take zyrtec with benadryl (diphenhydramine)?

Not really: These are both antihistamines. If both are needed then physician guidance should be sought. ...Read more

Dr. John Chiu
1,046 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. John Chiu Dr. Chiu
Internal Medicine - Allergy & Immunology
53 years in practice
University of Vermont College of Medicine
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Benadryl (diphenhydramine) knocks me out, will zyrtec do the same?

Benadryl (diphenhydramine) knocks me out, will zyrtec do the same?

Less likely: Although Zyrtec can cause drowsiness in 10-15% of the people, it is likely to cause much less drowsiness than Benadryl (diphenhydramine) which is often used as a sleep-aid in OTC medications. ...Read more

Dr. Brian Bezack Dr. Bezack
Pediatrics - Pulmonology
14 years in practice
New York Institute of Technology New York College of Osteopathic Medicine
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Taking zyrtec and Benadryl (diphenhydramine) at the same time okay?

Taking zyrtec and Benadryl (diphenhydramine) at the same time okay?

Depends: The combination can cause increased drowsiness; however, if you are taking zyrtec for allergies and you have an allergic reaction, you can take an additional benadryl (diphenhydramine). You should always discuss these interactions with your doctor. ...Read more

Dr. Paul Carter Dr. Carter
Internal Medicine - Allergy & Immunology
26 years in practice
East Tennessee State University James H. Quillen College of Medicine
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I took zyrtec at 5 pm and Benadryl (diphenhydramine) 9 pm is that ok?

I took zyrtec at 5 pm and Benadryl (diphenhydramine) 9 pm is that ok?

Yes: If you take the recommended dose, it should be okay to combine these two medications. ...Read more

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Dr. John Chiu Dr. Chiu
Internal Medicine - Allergy & Immunology
53 years in practice
University of Vermont College of Medicine
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Is it ok to take zyrtec after you've taken benadryl (diphenhydramine)?

Is it ok to take zyrtec after you've taken benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness ( the latter much less common if one uses the non-sedating type). ...Read more

Dr. Franklyn Gergits Dr. Gergits
ENT - Head & Neck Surgery
25 years in practice
Philadelphia College of Osteopathic Medicine
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Can you take zyrtec during day and Benadryl (diphenhydramine) at night?

Zyrtec and Benadryl (diphenhydramine): Hello. These two antihistamines taken together will probably cause sedation. As physicians, we often times double up on antihistamines in challenging cases but i usually use non-sedating antihistamines when I do this. There are other medications that may work better than this combination. Check with your doctor for other options. ...Read more

Dr. Michael Zacharisen Dr. Zacharisen
Internal Medicine - Allergy & Immunology
29 years in practice
Medical College of Wisconsin
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Is safe if i take Benadryl (diphenhydramine) six hours after take zyrtec?

Is safe if i take Benadryl (diphenhydramine) six hours after take zyrtec?

Should be ok: While taking Benadryl (diphenhydramine) after zyrtec should be ok, it would be even better to know the underlying trigger to allow less medication usage. An allergist could determine why symptoms are not controlled with less medication. ...Read more

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Dr. Brant Ward Dr. Ward
Internal Medicine - Allergy & Immunology
9 years in practice
University of Texas Southwestern Medical School at Dallas
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Should i take Benadryl (diphenhydramine) until my zyrtec really kicks in?

Probably not helpful: Both drugs need to be absorbed by the GI system before they take effect to stop itching and sneezing (can take up to 1 hr). Benadryl (diphenhydramine) can dry up mucus (and make you sleepy), which zyrtec will not do at any time. If you have taken zyrtec for several days without relief from itching or sneezing, you may have something besides allergies (e.g. A cold) or need a different treatment. See your doctor. ...Read more

Dr. Yash Khanna Dr. Khanna
Family Medicine
53 years in practice
University of Lucknow, K. G. Medical College
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I had zyrtec about 6 hours ago. Can i take Benadryl (diphenhydramine) now?

Yes you can: Yes you can if your symptoms are not controlled with zyrtec (cetirizine) alone for short period. ...Read more

Dr. Doanh Nguyen Dr. Nguyen
Internal Medicine - Allergy & Immunology
10 years in practice
University of Texas Medical School at Houston
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Is it possible for you to take zyrtec and Benadryl (diphenhydramine) in the same day?

Is it possible for you to take zyrtec and Benadryl (diphenhydramine) in the same day?

Yes you can: You can take both medications at the same time providing that you follow the recommended otc doses. ...Read more

Dr. Yash Khanna Dr. Khanna
Family Medicine
53 years in practice
University of Lucknow, K. G. Medical College
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Can you tell me is it ok to take zyrtec for daytime and Benadryl (diphenhydramine) for night?

Can you tell me is it ok to take zyrtec for daytime and Benadryl (diphenhydramine) for night?

Yes it is ok: Yes it is ok as long as you are using it for short period when your allergy symptoms are not controlled with zyrtec (cetirizine) and you are not able to sleep due to allergy symptoms. ...Read more

Dr. Nayla Mumneh Dr. Mumneh
Internal Medicine - Allergy & Immunology
25 years in practice
State University of New York Downstate Medical Center College of Medicine
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Well, i took Benadryl (diphenhydramine) about 12 hours ago and i was wondering, may i take zyrtec?

Antihistamines: Yes you can, but you really should have some doctor guidance with your medications, because you did not mention what symptoms you are treating with the antihistamines and they may not be the ideal medication if you are not responding to one and need to add another. Talk to your doctor. ...Read more

Dr. Tara Pernot Dr. Pernot
Internal Medicine
20 years in practice
University of Illinois College of Medicine
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I took a zyrtec about 12 hrs ago and was wondering if it was ok to take one benadryl (diphenhydramine)?

Yes: it is not harmful to take Benadryl (diphenhydramine) after Zyrtec- both medications are antihistamines and generally you would not need to take both of them Benadryl (diphenhydramine) is a stronger antihistamine and may help with symptoms unresolved by Zyrtec - it often has more sedation as side effect than Zyrtec ...Read more

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Dr. Ajay Pathak Dr. Pathak
General Practice
15 years in practice
Duke University School of Medicine
14

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Long term use of children's Benadryl (diphenhydramine) vs zyrtec. Which one works best with the least chance of becoming tolerant or non responsive ? Should i alternate

Allergy Meds: One should see an allergist to identify the allergens ang get appropriate treatment. Long term use of Benadryl (diphenhydramine) or zurtec specially at young age without physician supervision is harmful. ...Read more

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Dr. Tammi Schlichtemeier Dr. Schlichtemeier
Pediatrics
27 years in practice
University of Texas Southwestern Medical School at Dallas
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Is it safe to take both zyrtec and benadryl (diphenhydramine)?

Not a good choice: Benadryl (diphenhydramine) is a short acting antihistamine. Zyrtec is a long acting antihistamine. You may overdose if taking both at the same time or taking both in the same day. Consider a better allergy medication if zyrtec is not working well or if you have been taking Benadryl (diphenhydramine) longer than 5 days. ...Read more

Dr. Al Hegab Dr. Hegab
Internal Medicine - Allergy & Immunology
36 years in practice
Ain Shams University Faculty of Medicine
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Can i take zyrtec d and benadryl (diphenhydramine) at the same time?

Can i take zyrtec d and benadryl (diphenhydramine) at the same time?

Better not: Unless you have severe allergic reaction, and only once, otherwise it is not advisable, if you have uncontrollable allergies, better see an allergist, check aaaai.org or caai.org for an allergist in your area ...Read more

Dr. Nguyen Nguyen Dr. Nguyen
Pediatrics
46 years in practice
UCLA School of Medicine
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Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

No: Both zyrtec and Benadryl (diphenhydramine) belong to the same class of medicines called antihistamines. Taking both at the same time would be taking a double dose of medicine. Zyrtec is taken once every 12 hours, whereas Benadryl (diphenhydramine) is taken every 4 to 6 hours. ...Read more

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Dr. Holly Maes Dr. Maes
Pediatrics
32 years in practice
Medical College of Wisconsin
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Can you give a 8 month old zyrtec and Benadryl (diphenhydramine) in the same day?

Yes, but...: That's a lot of medicine for an 8 month old. Make sure it has been ok'd by your pediatrician, and this is not a good long term combination. If that little one has that severe of allergies, might consider adding a med like singulair (montelukast) to get allergies under control. Also, try to reduce exposure to the allergens rather than adding more medicine. ...Read more

Dr. Yash Khanna Dr. Khanna
Family Medicine
53 years in practice
University of Lucknow, K. G. Medical College
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What can occur if i took 2 Benadryl (diphenhydramine) and a zyrtec to help sleep before a big day?

Too much med: I don't think it is a good idea as it is too much antihistamine.I will recommend you discuss it with your doctor or allergist. ...Read more

Dr. Suzanne Galli Dr. Galli
Facial Plastic Surgery
20 years in practice
State University of New York Downstate Medical Center College of Medicine
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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. John Chiu
563 doctors shared insights

Cetirizine (Definition)

Ceftirizine is the generic name of an antihistamine previously marketed under the ...Read more