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Doctor insights on: Zyprexa And Cymbalta

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My Doc advised me Zyprexa 10mg, Depakote 500mg & Cymbalta 30mg since 1 week. My mood is going severely down. Nothing seems good. Everything is blue.

My Doc advised me Zyprexa 10mg, Depakote 500mg & Cymbalta 30mg since 1 week. My mood is going severely down. Nothing seems good. Everything is blue.

See doctor: You need to see your prescribing doctor without delay for assessment of meds and depression. Make clear that your depression is worse since starting meds. If you can't see doctor right away, go to urgent care. Be safe and take care. ...Read more

Cymbalta (Definition)

Cymbalta (duloxetine) is an "antidepressant" medication. However, it is an approved treatment for a variety of indications to include (unipolar) depression, anxiety, and chronic pain (related to diabetic neuropathy, musculoskeletal and/or fibromyalgia). Pharmacologically, it primarily enhances 2 different neurotransmitters (serotonin and norepinephrine). It can cause a ...Read more


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My Doc advised me Cymbalta 30mg, Paxil CR 25mg, Zyprexa 5mg, tizanidine 4mg for severe anxiety, panic, depression.I feel no improvement. advice please?

My Doc advised me Cymbalta 30mg, Paxil CR 25mg, Zyprexa 5mg, tizanidine 4mg for severe anxiety, panic, depression.I feel no improvement. advice please?

See ans: Reassess meds with prescribing doctor who knows you best. See your primary care doctor for any possible medical factors that might contribute to anxiety or depression symptoms: check thyroid, vit D, iron, etc. Consider psychotherapy for coping strategies and support. I hope this helps. ...Read more

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Could the combination of olanzapine and duloxetine be making me gain weight?

Could the combination of olanzapine and duloxetine be making me gain weight?

Maybe.: Olanzapine often causes weight gain and at times elevated blood sugar, cholesterol and triglycerides. It is a major side effect of olanzapine. Duloxetine can also cause weight gain but is less likely to do so. The weight gain on Olanzapine is almost immediate and may be progressive. Duloxetine's is not. It takes time and isuncommon and small. It is more likely the olanzapine. ...Read more

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Upon discontinuation, what is the likelihood that / how quickly should I expect to lose the 20 lbs gained while taking olanzapine/zyprexa?

Upon discontinuation, what is the likelihood that  / how quickly should I expect to lose the 20 lbs gained while taking olanzapine/zyprexa?

After Zyprexa wtloss: Most of the patients that I have switched off of Olanzapine and onto another drug were able to lose their weight. Those who exercised and dieted lost faster. I would guestimate that it will take you under three months if you work at it. Best wishes to you. Go packers! ...Read more

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Is 30mg of zyprexa considered an overdose for an adult?

Is 30mg of zyprexa considered an overdose for an adult?

Not as a one time: Typical doses of zyprexa are 2.5 to 20 mg a day. A one time dose of 30 mg, without other medication or substances, is not likely to cause too much damage other than severe sleepiness. ...Read more

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How long does zyprexa stay in the body sysyem?

How long does zyprexa stay in the body sysyem?

Seversl days: Well zyprexa is metabolized by the liver, excreted by the kidneys in urine, 57%, and in feces 30%. The key point however is that it has a 1/2 life of 21-54 hrs. Meaning it takes that long to eleminate 1/2 the drug from your system, then that long to eleminate 1/2 of what's left and so on till it's all gone. Some people rapidly metabolize zpxa hence the difference in 1/2 life & excretion rate. ...Read more

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Please describe the medication: zyprexa?

Please describe the medication: zyprexa?

Zyprexa: An atypical antipsychotic approved by fda for tx of schizophrenia & bipolar disorders. It is structurally similar to Clozapine but classified as thienobenzodiazepine. It is manufactured by eli lilly co. May cause involuntary movements, akathisia, fatigue, red eyes, dry mouth, anhedonia, dizziness, weight gain, seizures, metabolic changes such as diabetes. ...Read more

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What do you suggest if my husband won't take his zyprexa for schitzsophrenic and hes hard t deal with what do I do?

Well: thats always difficult, if he becomes a threat to himself or others take him to the ER or call 911. If not, then discuss oter treatment options with his psychiatrist such as long acting injectable medications. ...Read more

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Will i feel the difference from zyprexa to zalasta?

Will i feel the difference from zyprexa to zalasta?

MAYBE: You may experience a difference going from the brand zyprexa to the generic olanzepine. The generic can have a lower bioavailability so please speak to your physician about any noted changes. As an update I have been informed by dr. Alan ali that these meds are equivalent in usa and uk. So should not be a problem if the dosing is the same. ...Read more

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I take zyprexa to slow racing, repetitive thoughts. Tried to stop the medication but suffered relapse each time. Similar drugs i might take ?

You haven't provided: Your diagnosis. If you could provide this information - more specific response could be provided. Please clarify and re-ask. ...Read more

Dr. Alan Ali
206 doctors shared insights

Zyprexa (Definition)

An atypical antipsychotic approved by fda for tx of schizophrenia & bipolar disorders. It is structurally similar to Clozapine but classified as thienobenzodiazepine. It is manufactured by eli lilly co. May cause involuntary movements, akathisia, fatigue, red eyes, dry mouth, anhedonia, dizziness, weight gain, seizures, metabolic ...Read more


Olanzapine (Definition)

Also called zyprexa, is a second generation antipsychotic that works to alleviate symptoms of ...Read more