Doctor insights on:
Zyloprim Gout Agent
Very!: Allopurinol has been around for some time is is really quite safe. Rare side-effects do occur, but I have not seen them. When Allopurinol is started (or uloric) start at a low dose and work up. Lowering uric acid in the blood to0 quickly will precipate a gout attack, which is a major reason for using pre-dose Colchicine and/or an anti-inflammatory drug.Used properly, gouty arthritis need not be! ...Read more
Two options: Colchicine may control the acute attacks while other medicines are started to lower uric acid levels which will ultimately prevent gout. One choice would be uloric which is a daily pill. If that fails, Krystexxa (pegloticase) is an an option. Krystexxa (pegloticase) is more powerful than other drugs but is given by intravenous infusion every two weeks. ...Read moreSee 2 more doctor answers
Possibly: Agree with dr. Namey that the affect of Allopurinol on heart is still uncertain. One study showed improvement in patients hospitalized with congestive heart failure. Also, re drug-drug interaction, Allopurinol can interact with warfarin (coumadin) to increase bleeding risk. ...Read moreSee 1 more doctor answer
Allopurinol Chronic: For acute gout Colchicine and diclofenac are reasonable. Do not exceed the recommended dose of Colchicine and stop immediately if diarrhea occurs. Allopurinol is to prevent chronic gout. Many patients starting Allopurinol will have an acute gout attack because attacks occur when uric acid levels go up or down. To prevent this some patients take Colchicine daily for up to 6 months. ...Read moreSee 2 more doctor answers
I have a friend that has gout and is worried about the medication side effects, does anyone know the negative effects of allopurinol?
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