Doctor insights on:
Zosters And Methotrexate
Not a good idea: The shingles vaccincation (known as zostervax) is a live virus, therefore you would run the risk of infection from the vaccination itself. Any medication in the class of drugs like Humira (adalimumab) would be a no-no to receiving the shingles vaccine. This is the official published guidelines from rheumatologists that just came out in early 2012. ...Read moreSee 1 more doctor answer
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Since starting Accutane i've experienced more frequent herpesvirus outbreaks consisting of more lesions. Why? Valtrex (valacyclovir) and Accutane together?
Possibly related: There are some reports in the literature of increased h. Simplex perioral outbreaks with Isotretinoin use. Some dermatologists recommend pre-treatment with herpecidal medication (such as valtrex) for one week prior to starting Isotretinoin in those with a history of outbreaks. ...Read more
For rheumatologists, my mom's dr prescriped methotrexate, HQ, and prednisone plus Humira (adalimumab) q2wks for her RA..is that very strong drugs on her or normal?
"Normal" Combination: That is a reasonable combination.Get a more detailed answer ›
Is there another way to treat my psoriasis from psoriatic arthritis? So far have tried uv therapy, low dose radiation treatment, methotrexate, humira, enbrel, halabetasol ointment, coal tar, hylatopic, and any other cream my dermatologist could think of.
Wow: You have been through a lot. I would try the mayo clinic in mn. ...Read more
I take nabumetone, methotrexate, enbrel, plaquenil, vitamin d and folic acid for RA & dermatomyo. Which of these is making it difficult to lose wight?
Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more
Can topical steroid treatment be given in viral diseases like varicella, herpes, chicken pox infections?
Do medications (eg: lyrica, (pregabalin) prednisone, methotrexate, azathioprine) have any effect on a skin test for small fiber neuropathy?
Dx:ra. Enbrel (etanercept) not effective after 6 mo. Humira 2x mo prescribed. Liver can not tolerate mtx. What medication can replace mtx to make humira work best?
On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.
Follow laboratory: You are correct that liver problems are risk with this regimen. Your physician needs to be certain that you are followed closely and correctly. Your own responsibility is to refrain from alcohol, and be certain no additional medicines you take do not worsen this risk. If you are concerned you need to discuss this with your physician. There are other therapy choices available. ...Read more
Yes: Cytoxan (cyclophosphamide) can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan (cyclophosphamide) is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more
I've been prescribed cyclosporine for lupus. I also take Plaquenil (hydroxychloroquine) 400mg/day. Can the side effects of the latter be increased because of the former?
Dose dependent: This judgement has to be made by the provider. Technically low dose Methotrexate is not considered a contraindication to receiving the shingles vaccine. But only your provider will have a full picture of your immune status. Shingles vaccine is a live vaccine and not given to those with significant immunosuppression. ...Read more
See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read moreSee 1 more doctor answer
Is eczema an auto immune response? If so can drugs such as methotrexate and tnf blockers aid in the treatment of extreem cases?
Allergy Respons: Eczema is an allergy to something, often foods. Using immune suppressant drugs will clear the problem but it is better to find the cause and remove it or treat it than to suppress the immune system. Suppressing the immune system can be very dangerous. ...Read moreSee 1 more doctor answer
What are the dangers of long term use of prednisone for sle in low doses. Like 5mg. Got ezcema on hands from generic plaquenil (hydroxychloroquine). What are other options?
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