Doctor insights on:
Zonalon Tertiary Amine Tricyclic
Mostly: Wellbutrin (bupropion) interferes with reuptake of dopamine&norepinephrine(noradrenaline)in the central nervous system, thereby leaving these neurotransmitters to sit longer&stronger in the synapse between communicating brain cells, which enhances dopamine&adrenaline activity at the cellular level. That can treat depression, feed pleasure to help sex&bypass tobacco, improve adhd&cognition, lower weight, etc. ...Read moreSee 2 more doctor answers
TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more
Can periactin (cyproheptadine hydrochloride) (cyproheptadine) be useful in relieving serotonin induced migraine caused by an ssri? Periactin (cyproheptadine hydrochloride) has antiserotonin affinity. Head hurts..
Might be useful: Although Cyproheptadine is nominally an anti-histamine, it does have seratonin antagonistic effects, and, has been best used as a migraine preventative in years past. Since it is cheap, could try it, but likely should start low dose and aim for about 4mg every 6 hrs. May take about two weeks to decide success at the higher dose. ...Read more
Others preferred: In gereneral tricyclic antidepressants including Pamelor (nortriptyline) are relatively less safe than other classes of antidepressants. This is especially true if "cardiac disease" means recent (within approximately 6 months) heart attack. Zoloft (sertraline, an ssri) may be relatively safer. Untreated depression contributes to worsened prognosis for certain types of heart disease. ...Read more
Only noradrenergic antidepressant works for me, does inderal (propranolol) acts negative on noradrenergic effects of antidepressant ?At vasomotor centers.Regards.
Venlafaxine: It's not the vasomotor centers that are important in antidepressant response; it's the neuron synapses in the brain. Effexor (venlafaxine) inhibits reuptake of both serotonin and ne. Inderal can suppress some of the physical symptoms of anxiety (rapid heart rate, sweaty palms, tremulousness, etc). Some on chronic (not intermittent or "prn") Inderal have had more depression. Not everyone. You should be okay. ...Read more
Which causes asthenia after not taking; 1-Haloperidol
They're very similar: Elavil (amitriptyline) (amitripyline) and tofranil (imipramine) are both tricyclic antidepressants, an older category. While they are effective against depression, both can cause antihistamine-like effects e.g., sedation, dry mouth, dry eyes, constipation, and temporary trouble focusing vision. Elavil (amitriptyline) does this a little more, so tofranil may be better unless elavil's extra sedation helps. ...Read moreSee 3 more doctor answers
Which tcas is more potent for sciatica pain relief, amitriptyline(or nortriptyline), imipramine(or desipramine)?
TCA: Tca are classic for neuropathic pain - sciatica for example. Any of the ones u mentioned may be quite eefective - and cheap. They are not without side effects - dry mouth, constipation, sedation. Any of the ones u mentioned can be effective. I personally like amytryptilline - 10mg at night - as mentioned all will work. Additionally other meds such as lyrica, (pregabalin) neurontin, Cymbalta are options. ...Read moreSee 1 more doctor answer
Agree w Dr. Ali: Which is best for treating which condition?. Paxil is an SSRI antidepressant which is good for treatment of typical depressive sx 's & anxiety. Bupropion is a unique antidepressant which is good for seasonal affective disorder, atypical depression & smoking cessation. Oxcarbazepine is a mood stabilizer and olanzapine is an antipsychotic. You are asking us to compare apples & organges. ...Read moreSee 1 more doctor answer
Elavil (amitriptyline): Nope.Get a more detailed answer ›
No: Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults. It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in the european union. It was designed as a more potent successor to gabapentin. ...Read moreSee 2 more doctor answers
150 mg. Elavil (amitriptyline) for 25 years switch to ssri with greatest sedative affect as elavil (amitriptyline) - which ssri would be best suited for me?
Individual consult: To find something best suited to you, you need an individual re-assessment with your own doctor. There's no ssri as truly sedating as elavil (amitriptyline). In fact, this is partially why many ssri's are chosen over older antidepressants like Elavil (amitriptyline) anyway. People don't like to be drowsy in daytime. If you and your doctor are looking for sedation, an alternative (not an ssri) might be mirtazepine. ...Read moreSee 1 more doctor answer
5HTP vs SSRI's: People are intrigued with 5-htp because it can be decarboxylated to serotonin, a neurotransmitter with many important functions. There are some studies suggesting it can help with depression, especially combined with l-tyrosine. 5htp can certainly cause GI distress like ssri's can. However, there isn't enough evidence to say it equals ssri antidepressants in treating depression. 200-300mg/day. ...Read moreSee 1 more doctor answer
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
(Allegra, ortho tri-cyclen, Cymbalta)-GP prescribed.
(Baclofen, Carb/Levo, & Adderall)-added by Neurologist. Interact. b/w meds to cause hypnic jerks?
Reconciliation: If different doctors all use electronic medical records, and they perform "medication reconciliation" at each visit so that they all know what doctor prescribed which medication, likelihood is high that the systems alerts of any potential problems with the medications. The Affordable Care Act (=Obamacare) mandates medication reconciliation. ...Read more
Varies: Many of the tricyclic antidepressants have established blood levels that are associated with the best outcome. Rather than rely on a specific oral dose, i would have your physician order blood tests to determine the amount of the medication in your system and then adjust the oral dose according. ...Read moreSee 1 more doctor answer
Older depression med: This medication which includes many variants is named for the three rings that make up its chemical structure. Currently it has been mostly replaced by ssri drugs which have less side effects, it is still used to treat a variety of mood related disturbances. ...Read moreSee 1 more doctor answer
We don't know: Nearly all antidepressants turn out also to be good for treating anxiety too. We still do not understand exactly how they produce their effects on either depression or anxiety. Tricyclic antidepressants were among the first to be used widely; they are less commonly used now because they have more side effects than new antidepressants but can stil be very useful. ...Read moreSee 1 more doctor answer
Luvox (fluvox (fluvoxamine)amine) -the best ssri ever on in the past-but its interactions are to tricky to work with -having multiple conditions--what ssri is closest to luvox (fluvoxamine)?
Celexa, Lexapro (escitalopram): Newer ssris include citalopram (celexa) and escitalopram (lexapro), which is related to citalopram; both are structurally different from other ssris and other currently available antidepressants. Rec. Do not self medicate. See your physician for medication management. ...Read more
Rings: The designation refers to the chemical structure. Monocyclic antidepressants, such as bupropion or fluvoxamine, have a molecular structure with only one ring of atoms whereas tricyclic antidepressants, such as Imipramine and desipramine, have three rings of atoms in their structure. ...Read more
SSRI's vs Tricyclics: The ssri's focus on blocking serotonin reuptake, and the tricyclics are non-selective in their receptor activity. Histamine blockade and others in tca's causes more sedation; there can also be postural hypotension with tca's. Ssri's may be safer in overdose, less likely to cause arrhythmia -- could be important in patients w/heart disease. Ssri's have their own side effect profile though. ...Read moreSee 1 more doctor answer
I had a small amount of spotting. I am on tricyclic bc pills and have only had protected sex. What could the spotting be from?
Continue: You should continue taking it regularly. If you started taking this medication recently then your body needs time to adjust to it, spotting can be a side effect when you first start taking this kind of medication. ...Read more
This question is for a psychiatrist. is there any benefits for taking a tricyclic over an ssri. please expain, thanks?
Sometimes: Certain tricyclic antidepressants can help with insomnia because they are sedating. Some can help with pain management. In general - SSRI's tend to have a much better side effect profile. I seldomly use TCA's now - unless it is to help with sleep or pain. Take care. ...Read moreSee 1 more doctor answer
Neurotransmitters: Tricyclic antidepressants are probably the most effective antidepressants we have. They affect a number of neurotransmitters and multiple circuits in the brain, alleviating depression, anxiety, migraines, and various pain syndromes. The down side to them is side effects and potential for stopping the heart in overdose. The serotonin-norepinephrine antidepressants are much safer. ...Read more
Certain ones: In my practice and with my patients with various anxiety disorders, i often find the tricyclic antidepressant nortriptyline to be quite beneficial. Some doctors who did not receive their training until the 90s, may not feel comfortable prescribing some of the older medications. ...Read moreSee 1 more doctor answer
I took Dur amine 40mg can't sleep having trouble breathing is this normal does it pass please advise, what to do?
Can i experience antidepressant withdrawal when transitioning from a tricyclic to an ssri? If so, what are some of the symptoms?
Yes: Symptoms of gastrointestinal and somatic distress, sleep disturbance, and movement disorders and mania have been temporally linked to withdrawal of tcas. Cholinergic and adrenergic overdrive after tca discontinuation have been suggested as the proposed mechanism for this syndrome. Reported symptoms may be psychosomatic or related to underlying mental illness. www.ncbi.nlm.nih.gov/pubmed/8219442. ...Read more
Amitriptyline: Tryptizol is an international brand name for amitriptyline marketed in Egypt and Lebanon. Amitriptyline is a tricyclic antidepressant that may be helpful for anxiety disorders. However, there are safer meds, more widely used for anxiety, eg., SSRI serotonin - boosting, today. See: http://www.drugs.com/international/tryptizol.html ...Read more
TCAs replaced : Tricyclic agents (TCAs) are used primarily as antidepressants. The TCAs were first discovered in the early 1950s and were introduced later in the decade;[ In recent times, the TCAs have been largely replaced in clinical use by the newer antidepressants which have more favorable side-effects profiles. TCAs neg. effects are-- cognitive dully, danger if overdosed, wt. gain, CVS & antichol. effects ...Read more