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Doctor insights on: Zoloft Sertraline Take

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How long does Zoloft (sertraline) take to kick in at 150 mgs.?

How long does Zoloft (sertraline) take to kick in at 150 mgs.?

Hope you didn't: Start at 150 mg - and worked up to it. It often takes 4 to 6 weeks at an optimal dosage to really start feeling the effects. Occasionally it may start to kick in at 2 weeks. Take care. ...Read more

Dr. Heidi Fowler
1,094 Doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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How long can Zoloft (sertraline) take to get out of your system?

How long can Zoloft (sertraline) take to get out of your system?

Male or woman: Depends. Its half life is long. Average is considered about 24 hours just to get half of it out of your body. It may be 1.5 times longer in women. And, remember, the next 24 hours just gets half of the remaining half out of you. ...Read more

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How long will zoloft (sertraline) take to kick in? Its 4th day and I still am feeling anxious.

How long will zoloft (sertraline) take to kick in? Its 4th day and I still am feeling anxious.

Zoloft (sertraline): Would expect increase in serotonin levels by around 4 to 6 weeks. However, it will need to be determined if the dose you are on is optimum at that time. Take care & be patient. ...Read more

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I am on 60mg of stattera and 125mg of zoloft (sertraline). I take zoloft (sertraline) at night but both make me drowsy. Can I take them together?

I am on 60mg of stattera and 125mg of zoloft (sertraline). I take zoloft (sertraline) at night but both make me drowsy. Can I take them together?

If you don't have: ADHD, why did your psychiatrist add Strattera (atomoxetine) to Zoloft for you Anxiety Disorders? The combination ^es risk of Serotonin Syndrome - sweating, tremor, fever, tachycardia & more, if severe, & of prolonged QT interval on EKG, which can lead to cardiac arrhythmia. Don't take St. John's Wort with these. Don't taper either medication on your own. Ask your psychiatrist about benefits vs. Risks. ...Read more

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Does Tramadol have as much SSRI in it as Zoloft (sertraline)? I take 100mg of Tramadol a day. Does 100mg of Tramadol have as much SSRI as say 50mg of Zoloft (sertraline)?

Does Tramadol have as much SSRI in it as Zoloft (sertraline)? I take 100mg of Tramadol a day. Does 100mg of Tramadol have as much SSRI as say 50mg of Zoloft (sertraline)?

Psych fx of Tramadol: Tramadol is not a selective serotonin reuptake inhibitor. It cannot be directly compared to Zoloft (sertraline).
In addition to activating some types of opiate receptors, tramadol does exert serotonin and norepinephrine reuptake inhibition at clinically-used doses.

Tramadol combined with SSRI meds can trigger the serotonin syndrome.

Tramadol may have antidepressant fx, but is definitely an off-label use. ...Read more

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I can't remember if I took my nightly dose of Zoloft (sertraline). I take 150mg at bedtime every night. I am experiencing lots of PVC's currently and am anxious.?

I can't remember if I took my nightly dose of Zoloft (sertraline). I take 150mg at bedtime every night. I am experiencing lots of PVC's currently and am anxious.?

Don't double-up: Try to find a more fool-proof method to remember your medication, but do not take another dose unless it is only a few hours late. Missing one dose should not cause a problem - you have lots in your system from earlier. Some (most) of the symptoms you felt so soon were psychologically based - it's the opposite of the placebo (nocebo). Both are quite powerful! You can take today's a bit early. ...Read more

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Spotting is more common for me since I started taking Zoloft (sertraline). I take seasonal birth control but I haven't taken a break to have my period in 6 months?

Spotting is more common for me since I started taking Zoloft (sertraline). I take seasonal birth control but I haven't taken a break to have my period in 6 months?

Breakthrough bleed: Unscheduled bleeding is a common side effect of any birth control method but very common on low dose pills. It usually corrects itself in a few days or over a couple of cycles. If not then you will need to schedule a visit to discuss changing brands or changing methods and make sure nothing else is wrong. Other than being annoying for you it is not harmful. ...Read more

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What is the average dosage of Zoloft (sertraline) people should take?

What is the average dosage of Zoloft (sertraline) people should take?

Zoloft (sertraline): Up to 200mg. Per day in divided dosages, for average adult. ...Read more

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I'm taking Zoloft (sertraline) 50mg. I take the pill at 2pm every day. If I'm an hour late, is it okay to take it anyway at 3 and continue to take it the following day at 2pm? What hapoens if I'm 2 hours late? 3 hours?

Take it, anyway: Very likely that you will feel nothing at all. Following a routine helps one remember more reliably, so get back to your routine, after you've made sure of no missed dose. ...Read more

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Are diphenhydramine and Zoloft (sertraline) bad to take together?

Are diphenhydramine and Zoloft (sertraline) bad to take together?

OK but Caution: Benadryl (diphenhydramine) together with sertraline may increase side effects such as dizziness, drowsiness, & difficulty concentrating. Some people may also experience some impairment in thinking & judgment. You should avoid/limit use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. Max Benadryl (diphenhydramine) dose is 300mg/d. ...Read more

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I took 100 mgs of Zoloft, (sertraline) can I take 800 mgs of Advil?

I took 100 mgs of Zoloft, (sertraline) can I take 800 mgs of Advil?

Occasional use: From drug-drug interaction, the combination does not raise concerns - if the Advil use is limited.
800 mg is a high dose though - that alone could cause stomach problems. Regular use of Advil has its own risks. Regular use, along w Zoloft, (sertraline) can increase risks of stomach bleeding. NSAIDs in general can exert either positive or negative psychotropic actions in a small number of sensitive individuals ...Read more

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Is it safe to take bentonite clay while on Zoloft (sertraline) if I take them several hours apart?

Bentonite clay: Bentonite clay binds many drugs in the intestine and therefore prevents the absorption of the drug. There will be less problem if they are several hours apart, but there is variability of intestinal movement, so the results are somewhat unpredictable....I.E. How much zoloft (sertraline) would actually be absorbed and how much bound by the clay. ...Read more

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I am constantly tired on zoloft (sertraline). I currently take it in the morning, is it possible if I switch to take it at night this will help with fatigue?

I am constantly tired on zoloft (sertraline). I currently take it in the morning, is it possible if I switch to take it at night this will help with fatigue?

It could: If zoloft (sertraline) makes you sleepy or fatigued, taking it at night may decrease this effect. Tiredness and fatigue can also be symptoms of depression, though. Not knowing how you were before beginning the medication, it's hard to know which is happening (ongoing depression or side effects from zoloft (sertraline)). Best to speak with your physician so s/he can advise you better. ...Read more

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If I take zoloft, (sertraline) can I take gas x?

If I take zoloft, (sertraline) can I take gas x?

Zoloft (sertraline): Yes you can take gas-x with zoloft (sertraline) but you should not take them at the same time---separate the doses by at least one hour. ...Read more

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Dr. Prescribed Ultram and Soma for chronic back pain, when needed, just recently he put me on zoloft (sertraline). Safe to take together or which combo to avoid.

Dr. Prescribed Ultram and Soma for chronic back pain, when needed, just recently he put me on zoloft (sertraline). Safe to take together or which combo to avoid.

Drug interaction: It is not recommended to mix tramadol with antidepressants such as zoloft (sertraline) due to increased risk of developing serotonin syndrome. Soma and zoloft (sertraline) can cause drowsiness. Please talk to your doctor before taking these medications together. ...Read more

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Is it True that you can't take Ibuprofen while on Zoloft (sertraline)? I only take it when I have a cold. Can I take it? I don't have acetaminophen. Any dangers?

Is it True that you can't take Ibuprofen while on Zoloft (sertraline)? I only take it when I have a cold. Can I take it? I don't have acetaminophen. Any dangers?

Possible interaction: Although there is a possible interaction that doesn't necessarily mean they can't be used together. 'Using sertraline together with ibuprofen may increase the risk of bleeding. The interaction may be more likely if you are elderly or have kidney or liver disease.' (http://www. Drugs. Com/interactions-check. Php? Drug_list=1310-0, 2057-1348) ...Read more

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I am having headaches body aches fatigue neck pain stomach pain and sweats with my 50mg Zoloft (sertraline) shld I take it @ nite vs day? Took first dose this am

Reduce starting dose: This may not necessarily be a side effect of the Zoloft (sertraline)--you may be coming down with a viral illness that is causing the symptoms.

Assuming that this IS a series of Zoloft (sertraline) side effects, (entirely possible), I'd try cutting the dose in half for a few days, then increasing the dose if you encounter no problems at the lower dose. ...Read more

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What is it like to take zoloft (sertraline)?

Dr Martínez-Irizarry: Is right. It is well tolerated in general but possible side effects start right away. Getting the full benefit of the medication - usually takes 4 to 6 weeks once on optimum dose. It is important to know this so that you are patient. It can be helpful for tx of treatment of major depressive disorder, panic disorder, social anxiety disorder, post traumatic disorder, obsessive compulsive disorder ...Read more

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When is best time to take zoloft (sertraline)?

Zoloft (sertraline): With meals, on full stomach, usually with breakfast & dinner, unless otherwise specified by your doctor. ...Read more

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Is it better to take Zoloft (sertraline) in am or pm?

Is it better to take Zoloft (sertraline) in am or pm?

Neither: It's more important to take sertraline at a consistent time that works for you. If it's easier to remember to take in the am, then consistently take it every am. ...Read more

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Best to take Zoloft (sertraline) in morning or at night?

Best to take Zoloft (sertraline) in morning or at night?

Usually at night: Usually zoloft (sertraline) is calming and facilitates sleep even though it isn't a sleep aid. But a minority of people feel more awake and can't sleep after taking it. They need to take it in the morning. So, start out by taking it at night and, if it keeps you up, start taking it in am. ...Read more

Dr. Heidi Fowler
1,048 Doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more


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