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Doctor insights on: Zoloft Sertraline Dosage

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Would side effects be present with increasing Zoloft (sertraline) dosage of 25 to 50mg? Although no bad side effects when taking 25mg, but many with 50mg.

Would side effects be present with increasing Zoloft (sertraline) dosage of 25 to 50mg? Although no bad side effects when taking 25mg, but many with 50mg.

Maybe: In my practice, i start most adults on zoloft (sertraline) at 50 mgs daily, and they do well. I then have them increase the dose to 100 - 200 mgs gradually, so they can be at a therapeutic dose. If you are having side effects now, see your physician and discuss all of your medications, over the counter medicines, and concerns. It may be that your side effects are due to medication interactions. ...Read more

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Dr. Donald Jacobson
1,039 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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Is dosage of Zoloft (sertraline) equivalent to dosage of prozac?

Is dosage of Zoloft (sertraline) equivalent to dosage of prozac?

No: There is not a 1:1 relationship between doses of zoloft (sertraline) and prozac. Zoloft (sertraline) doses range from 25 to 200mg whereas Prozac ranges from 10mg to 80mg. ...Read more

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What is the average dosage of Zoloft (sertraline) people should take?

What is the average dosage of Zoloft (sertraline) people should take?

Zoloft (sertraline): Up to 200mg. Per day in divided dosages, for average adult. ...Read more

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Can I still take Zoloft (sertraline) that is six months passed the expiration date? 50mg dosage.

Should be OK: Expiration dates tend to be artificial. It is not like one say the medicine is fine and the next day it goes bad. Over time a medication may gradually lose some of its potency but most likely Zoloft (sertraline) that is 6 months past the expiration date is still very potent and should still be as effective as if it was prior to the expiration date. If it was 2 or 3 years after exp. date I would reconsider... ...Read more

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Is it possible to only need 25 mg dosage of zoloft (sertraline). Taking it for 7 days, feeling better. Do i need to increase to prescribed 50 mg?

Is it possible to only need 25 mg dosage of zoloft (sertraline).  Taking it for 7 days, feeling better. Do i need to increase to prescribed 50 mg?

Zoloft (sertraline): Not knowing your age, weight, other meds and health status, it is hard to say. This medication takes up to 4 weeks to get to steady state. Since you have such early positive effects, it would not be a bad idea to talk to your doctor about staying for another week at 25mg. How you are feeling in an important indicator to the meds effectiveness. ...Read more

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Hi, I normally take a 100mg of Zoloft (sertraline) daily but today I accidentally took two of the 100mg pills making the dosage 200mg. Should I do something?

Hi, I normally take a 100mg of Zoloft (sertraline) daily but today I accidentally took two of the 100mg pills making the dosage 200mg. Should I do something?

Yes: Be more careful. 200 mg of Zoloft (sertraline) never killed anybody. Skipping tomorrow shouldn't disrupt the effect of the drug. BUT: Call your doctor and let him/her know. Don't personalize this: He/she's your doctor, not yout mother. ...Read more

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Could splitting Zoloft (sertraline) tablets lead to recurrence of mdd symptoms due to dosage discrepancies? Was trying to use leftover pills my dr. Had me split.

Could splitting Zoloft (sertraline) tablets lead to recurrence of mdd symptoms due to dosage discrepancies? Was trying to use leftover pills my dr. Had me split.

Not necessarily: It depends if you are splitting the pills and now taking too low of a dose- that could cause a recurrence of depressive symptoms. But in general, it should be ok to split sertraline. The pills have a "score" which means it intends for the patient to cut or split it. ...Read more

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I have been on Zoloft (sertraline) since april of 1998, been on max dosage awhile w/no problems. Threw up after taking normal dosage last night. Please help.

I have been on Zoloft (sertraline) since april of 1998, been on max dosage awhile w/no problems.  Threw up after taking normal dosage last night.  Please help.

See doc if repeats: You can't blame it on the medication if you throw up 1x in 12 years after taking medication. If it happens again see your physician. If you are going to change dosages you should review the plan with the treating doctor. ...Read more

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Dr. Alan Ali
991 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more