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Doctor insights on: Zoloft Lexapro Escitalopram

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I suffer from generalized anxiety with dep Through the years zoloft,lexapro (escitalopram) and effexor(because of BP) lost efficacy.Is there anything else I can take?

I suffer from generalized anxiety with dep Through the years zoloft,lexapro (escitalopram) and effexor(because of BP) lost efficacy.Is there anything else I can take?

Therapy?: Have you yet tried any form of psychotherapy? Typically, the optimal combination of things to treat emotional issues such as anxiety or depression is medication (which, on your best day, is supposed to take the edge off symptoms) but the real gruntwork takes place in psychotherapist's consulting room. ...Read more

Dr. Heidi Fowler
1,088 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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I have been diagnosed with gad & have tried zoloft, lexapro, (escitalopram) citalopram and remeron all to no avail. Would gabapentin be a good choice?

I have been diagnosed with gad & have tried zoloft, lexapro, (escitalopram) citalopram and remeron all to no avail. Would gabapentin be a good choice?

Probably not: In my experience, I have not seen Gabapentin to be useful in treating anxiety. Makes sure that your diagnosis is correct, and that you have been taking full, therapeutic doses of the medications you have been taking.
You may need a combination of medications, such as the addition of an antipsychotic.
Lastly, consider a second opinion with a different psychiatrist. ...Read more

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What is the difference between Zoloft and lexapro (escitalopram)?

What is the difference between Zoloft and lexapro (escitalopram)?

Not much: Both are selective serotonin reuptake inhibitors, or ssris, a fancy way of saying they help your brain hold onto and use more of the serotonin it has. Serotonin is one of the chemicals in your body related to happy things, like food, sex, and sleep (which is why the side effects often affect these issues).
Celexa, prozac, Paxil (paroxetine) are also in class.
Diff comes in personal brain chemistry + med. ...Read more

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What are the differences between Zoloft and lexapro (escitalopram)?

What are the differences between Zoloft and lexapro (escitalopram)?

Different SSRIs: Both belong to the selective serotonin reuptake inhibitor or ssri family, same as the old prozac. Lexapro (escitalopram) works faster, in days, but sometimes makes people more "hyper" or "jumpy." zoloft needs 2-3 weeks to have an effect. It has more weight gain and sexual side effects, but in general is better tolerated. They both can be used for anxiety and/or depression in doses that depend on your sx. ...Read more

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I switched from Zoloft to Lexapro (escitalopram) after a week on zoloft. Can i still count that towards time till i feel benefits or do I have to start over?

I switched from Zoloft to Lexapro (escitalopram) after a week on zoloft. Can i still count that towards time till i feel benefits or do I have to start over?

YES: Basically it takes 4-6 weeks for the medication to reach a steady state peak but improvement may be before that. So yes start over with the lexapro (escitalopram). ...Read more

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How is Luvox different from Zoloft or lexapro (escitalopram)?

How is Luvox different from Zoloft or lexapro (escitalopram)?

Luvox, Zoloft, (sertraline) and : Lexapro (escitalopram) are all SSRIs. They're all 1st line agents in tx of anxiety and depression. They all work via the same mechanism -- inhibiting re-uptake of serotonin, thus increasing serotonin concentrations. the differences between the meds have to do with subtle differences in half life, serotonin receptors targeted, and slight differences in side effect profiles. Talk with ur doc abt the right med 4u! ...Read more

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Switching from Zoloft to lexapro (escitalopram). Worried Lexapro (escitalopram) will make me dizzy? How common is dizziness so worried.

Not any more common: Dizziness is not any more common an effect than it is for zoloft. If you didn't have the effectin zoloft it is likely that it will not occur on lexapro (escitalopram). ...Read more

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Straight switch from Zoloft to lexapro (escitalopram). Doc told me to just switch without tapering off. Is this ok. Was on 150mg Zoloft going to 20 mg of lexapro (escitalopram).

Zoloft to Lexapro (escitalopram): Many physicians will do a cross taper gradually lowering the dose of one antidepressant while raising the dose of another. If however it has been determined that the zoloft has been of absolutely no benefit than there is no need for a cross taper. The Lexapro (escitalopram) should block any possible ssri discontinuation syndrome. Discontinuation symptoms with zoloft have been reported to be 1 to 2% but in my clinical experience have actually been far less than that. You should have no problem doing this. Best wishes. ...Read more

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Is it okay to switch from Zoloft to Lexapro (escitalopram) for panic disorder/agoraphobia?

Is it okay to switch from Zoloft to Lexapro (escitalopram) for panic disorder/agoraphobia?

If it is approved by: Your prescribing provider. Both are selective serotonin reuptake inhibitors. Lexapro (escitalopram) is approved for treatment of major depression ; generalized anxiety disorder but some doctors use it off label for panic disorder ; agoraphobia. ...Read more

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In general, do you prefer Zoloft or Lexapro (escitalopram) for GAD, panic, agoraphobia? I of course worry about side effects - prolonged qt interval - read too much!

In general, do you prefer Zoloft or Lexapro (escitalopram) for GAD, panic, agoraphobia? I of course worry about side effects - prolonged qt interval - read too much!

GAD and medication: Please do what your doc asks but consider adding a behavioral approach to address the root of the situation such as clinical hypnosis, biofeedback, psychotherapy. See www.asch.net for licensed providers who do clinical hypnosis and www.relaxationresponse.org for some self-help. Peace and good health. ...Read more

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What steps should I take from going down of Zoloft 200 mg to Lexapro (escitalopram) 10 mg?

What steps should I take from going down of Zoloft 200 mg to Lexapro (escitalopram) 10 mg?

Dr's job: Doctors diagnose and prescribe. That's the way it ought to work. You provide honest descriptions of what's happening then they make honest, well managed prescriptions. So far our society does not recognize do-it-yourself prescription privileges. Work together and good luck. ...Read more

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Doc told me to switch from 150 mg Zoloft to 20 mg Lexapro (escitalopram) without weaning just switch. Is that ok? Worried i will withdrawl.

Doc told me to switch from 150 mg Zoloft to 20 mg Lexapro (escitalopram) without weaning just switch. Is that ok? Worried i will withdrawl.

Switching SSRI's: You may be fine, since both these medications are ssri's. However, it's also possible to cross-taper these medications (decreasing zoloft while gradually increasing lexapro (escitalopram)). Not everyone needs 20 mg of lexapro (escitalopram). ...Read more

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Do i need to wean off Zoloft when switching to Lexapro (escitalopram) or can I just go straight to the Lexapro (escitalopram) without still taking zoloft. Doc said to do that?

Do i need to wean off Zoloft when switching to Lexapro (escitalopram) or can I just go straight to the Lexapro (escitalopram) without still taking zoloft. Doc said to do that?

Start Lexapro (escitalopram): While still on the zoloft . I usually have someone start on a small dose of the Lexapro (escitalopram) and increase it gradually while at the same time, taper down even more slowly on the zoloft. Each new antidepressant essentially has to start over again and needs time to work. Therefore you don't want to go off the zoloft too quickly, you may find out it had been doing much more for you than you had thought. ...Read more

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28yo fem w/ depression, anxiety. Zoloft for ~10 yrs, 50mg then 75. Added welbutrin. Zoloft quit helping, tried lexapro (escitalopram). Big weight gain. Rec new drug?

28yo fem w/ depression, anxiety. Zoloft for ~10 yrs, 50mg then 75. Added welbutrin. Zoloft quit helping, tried lexapro (escitalopram). Big weight gain. Rec new drug?

Antidepressants best: Another antidepressant, possibly snri like Effexor (venlafaxine) may be more helpful at this time. Add ons such as gaba- calm and natural anxiety aids can help. They do cause weight gain usually. Therapy is always an important treatment modality for depression and anxiety, don't think it is not helpful! ...Read more

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Can i take Lexapro (escitalopram) and Zoloft together?

only: Only if your dr prescribed it this way; the only normal situation to do this is because you are decreasing one and increasing the other (cross taper) with the goal of eventually end up with only one. Do not start/stop/mix meds without asking prescribing dr. Good luck. ...Read more

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20 mg of Lexapro (escitalopram) is equivalent to how much zoloft?

Zoloft vs Lexapro (escitalopram) : We really don't have equivalency charts for the antidepressants. By clinical experience, however, i would guess that 20 mg of Lexapro (escitalopram) is roughly equivalent to 100 mg or more of zoloft. Best wishes. ...Read more

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I want to switch back to Lexapro (escitalopram) from zoloft. Is that ok?

I want to switch back to Lexapro (escitalopram) from zoloft. Is that ok?

Generally yes: Obviously you should talk to your prescribing doc, don't switch behind their back. They need to know what you're taking, & may have other options to suggest. But yes, it's usually safe & easy to switch between Lexapro (escitalopram) & zoloft. Note that the dosages (mg) are different. Also, zoloft is available as generic while Lexapro (escitalopram) isn't, so Lexapro (escitalopram) costs more & insurance may not cover it. ...Read more

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How long does it take to adjust when switching from Lexapro (escitalopram) to zoloft?

How long does it take to adjust when switching from Lexapro (escitalopram) to zoloft?

Not long usually.: If the doses are equivalent then there should not be discontinuance symptoms. If the doses are not equivalent, then you could have recurrence of symptoms or you could have side effects from too high a dosage. 3-7% of the population cannot make the switch easily due to different metabolic rates of these two medications. You need to bring your symtoms to your doctors attention. ...Read more

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Will it be hard switching from 100mg of Zoloft for 6 wks to lexapro (escitalopram)???

Zoloft to Lexapro (escitalopram): Making the change from Zoloft to Lexapro (escitalopram) should not be too difficult as long as it's done under a doctor's supervision. You will essentially reduce the daily dose of Zoloft while you increase the daily dose of Lexapro (escitalopram) as your doctor instructs you. You will continue this titration until you are totally off the Zoloft and only on your final daily dose of Lexapro (escitalopram). The process might take 2-3 weeks. ...Read more

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I overdosed on 2300 mg of Zoloft, then a day later, I did 2100mg of Zoloft and 140 mg of Lexapro (escitalopram).

I overdosed on 2300 mg of Zoloft, then a day later, I did 2100mg of Zoloft and 140 mg  of Lexapro (escitalopram).

Overdoses: You are taking potentially lethal doses of medication. Are you suicidal? Call 911 or go to ER immediately. Call National Suicide Prevention Life Line at 1-800-273-8255. ...Read more

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Cross tapered from Lexapro (escitalopram) to Zoloft 4 weeks ago. Now taking (for 2 1/2 weeks)150 mgs zoloft..When should it kick in.Felt good1daythisweek.Thanku?

Up to 4 weeks: from experience starting or changing an SSRI may tale up to 4 weeks to get the desired result give it a little more time then if not working see your physician. ...Read more

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My dr said i could be off of Zoloft for 24 hours and then start 10mg Lexapro (escitalopram) is that safe been on Zoloft for about 15 years on 100mg since sept.2013?

They r SSRIs: I've switched pts directly from one sari to another--usually no problem--paxil can be a problem discontinuing bit others are usually ok. ...Read more

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What are the side effects of switching from Lexapro (escitalopram) to zoloft?

None: There should be no side effects caused by the switch per se. Since each person has different sensitivities, you may experience a side effect on zoloft you did not experience on lexapro, (escitalopram) where someone else experiences side effects on Lexapro (escitalopram) but not on zoloft. Usually side effects to these drugs are mild and transitory. Talk to your doctor about any discomfort you experience. ...Read more

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What are the side effects of switching from Lexapro (escitalopram) to zoloft, howling do they last .?

What are the side effects  of switching from Lexapro (escitalopram) to zoloft, howling do they last .?

Depends: Lexapro (escitalopram) and zoloft are both ssris and have the same side effect profiles, though any individual might have some side effects to one that she didn't have to the other. Most discomfort people experience in switching from one ssri to another is due to discontinuation from the first med, if the second one isn't at a sufficient level to avoid those discontinuation effects. Give it 3 weeks. ...Read more

Dr. Heidi Fowler
1,043 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more


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