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Doctor insights on: Zoloft And Ptsd

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I'm on Zoloft for ptsd and anxiety. Would dosing in the AM be more beneficial for symptoms as opposed to PM dosing?

I'm on Zoloft for ptsd and anxiety. Would dosing in the AM be more beneficial for symptoms as opposed to PM dosing?

Depends : Zoloft is since daily medication. It can generally be taken any time of day, with or without food. But, everyone responds a little differently. For instance, some people might get sleepy with it and take it at night. Others may have difficulty sleeping and have to take it in the morning. As long as you find a time of day that works best for you and is most convenient to remember, that's great. ...Read more

Dr. Donald Jacobson
1,039 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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I'm on my 3rd day of 25mg Zoloft (sertraline) for ptsd and ocd. Morning dosing and feel so tired by afternoon. Can Zoloft (sertraline) cause this fatigue?

I'm on my 3rd day of 25mg Zoloft (sertraline) for ptsd and ocd. Morning dosing and feel so tired by afternoon. Can Zoloft (sertraline) cause this fatigue?

Zoloft (sertraline) side effect: Zoloft (sertraline) doesn't always cause fatigue, but it is possible. Some people take Zoloft (sertraline) at bedtime, but it would be best to discuss this change in timing with your prescriber. Also, often the side effects that people have from Zoloft (sertraline) and other antidepressants resolve after the first 5-7 days on the medication, as your body adjusts to the medication, so keep this in mind as well. ...Read more

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Started Zoloft (sertraline) for ptsd and quit self medicating with alcohol. Its been 4 days alcohol free but i'm sleeping constantly and feel exhausted.

Started Zoloft (sertraline) for ptsd and quit self medicating with alcohol.  Its been 4 days alcohol free but i'm sleeping constantly and feel exhausted.

It may take your: Body a while to adjust to the changes. Congratulations on making this decision. It will take a while for the zoloft (sertraline) to reach a therapeutic level - so be patient. Take care. ...Read more

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Are there any medications for ptsd other than zoloft (sertraline)? What is the maximum dosage for zoloft (sertraline)?

Are there any medications for ptsd other than zoloft (sertraline)? What is the maximum dosage for zoloft (sertraline)?

Max 200mg per day: There are a number of ssri's that can work similar to the same way zoloft (sertraline) does, but zoloft (sertraline) has some stronger research behind it for ptsd. You can ask your physician to try other ssri medication. However, make sure, with ptsd, that you include therapy and include a support system. This is not something that should be dealt with by meds only. Best of luck and i hope that helps. ...Read more

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How can one drug, like zoloft, (sertraline) be prescribed for so many different conditions?-dep, anx, ocd, ptsd etc etc

How can one drug, like zoloft, (sertraline) be prescribed for so many different conditions?-dep, anx, ocd, ptsd etc etc

Antidepressant : Nobody knows for sure how this type of medicine works. However, it is well known that the drug interacts with receptors in the brain and block serotonin reuptake in the synaptic cleft, making it more available . Therefore, it is conceivable that many mental illnesses that are affected by serotonin could benefit from one drug. ...Read more

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Is there any safe meds to help a girl in the bedroom? I have trouble getting/staying in the mood. I am being treated for ptsd now and taking zoloft (sertraline).

Is there any safe meds to help a girl  in the bedroom? I have trouble getting/staying in the mood. I am being treated for ptsd now and taking zoloft (sertraline).

PTSD & Sex: Depending on the situations experienced, ptsd can certainly affect desire for & enjoyment of sex. Numbing symptoms can interfere; flashbacks of previous rape or childhood sexual abuse can directly impact ability to "stay in the mood." hopefully you have a compassionate partner who cares for you? With therapy, healing is possible -- and doesn't need to be rushed w/meds claiming to enhance sex. ...Read more

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Been on Klonopin 0.5mg for 6 months for PTSD. Also on 200mg Zoloft (sertraline) and in therapy. When should I start to taper off the Klonopin and how fast?

Been on Klonopin 0.5mg for 6 months for PTSD. Also on 200mg  Zoloft (sertraline) and in therapy. When should I start to taper off the Klonopin and how fast?

Depends: Staying on or stopping meds for PTSD should be tailored to your unique situation and discussed with your prescribing doctor. Your therapist should be aware of any med changes as well. That said discuss with your doctor to make sure this is the right time for you to stop Klonopin (clonazepam) and let him/her guide you on how best to stop. Hope this helps. ...Read more

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I'm taking prazosin for nightmares from PTSD and my doctor took me of Zoloft (sertraline) and put me on amatryptolin. Do I need to worry about them crossing ?

I'm taking prazosin for nightmares from PTSD and my doctor took me of Zoloft (sertraline) and put me on amatryptolin. Do I need to worry about them crossing ?

Crossing??: If you mean "interacting "when you say the word "crossing "then, are you referring to the interaction between praise a sin and amitriptyline? If that is your concern then, you should be fine. Not sure why any change was made to the Zoloft (sertraline) if prison was added newly but that's what your doctor decided to do. ...Read more

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I've got ptsd. I don't have $ to buy my zoloft (sertraline). Been having extreme spells of shaking, anxiety, depression, etc (no suicide or harm) any tips?

I've got ptsd. I don't have $ to buy my zoloft (sertraline). Been having extreme spells of shaking, anxiety, depression, etc (no suicide or harm) any tips?

$4 genRx + talk w/MD: Tell prescribing md any barriers to care, eg cost of meds. Never change/stop rxs unless advised by md. Some pharmacies, eg target, have list of $4/month generics, incl. Some similar to zoloft, (sertraline) eg citalopram, fluoxetine. Discuss w/prescribing md to see if okay to change to a rx on a "$4 list." also, discuss and make a plan w/md/therapist(s) for how to manage/cope w/symptoms until they get better. ...Read more

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Dr. Alan Ali
991 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more