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Doctor insights on: Zoloft And Orgasms

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Just started Zoloft (sertraline) & wow, orgasms are impossible! Sucks. Anything I can do (take) to fix? Besides switching-enough side effects already.

Just started Zoloft (sertraline) & wow, orgasms are  impossible! Sucks. Anything I can do (take) to fix? Besides switching-enough side effects already.

Switch.: The SSRI group can cause sexual dysfunction for some individuals, both male and female., When it occurs there are three alternatives. First, switch to a different SSRI. Second, reduce the dose and add Wellburtrin. Third, switch to Wellburtrin. ...Read more

Orgasm (Definition)

Conventionally, orgasm is the culmination of sexual arousal (and may be repeated) and typically produces great pleasure through direct genital stimulation of the male penis and female clitoris. However, orgasm may also be achieved via the brain or as a reflex arc. The physical characteristics are an explosive peak & repeated neuromuscular action causing release of male ...Read more


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Can Wellbutrin (bupropion) be taken simultaneously with Zoloft to eliminate difficulty orgasming side effect?

Can Wellbutrin (bupropion) be taken simultaneously with Zoloft to eliminate difficulty orgasming side effect?

Yes: Zoloft (sertraline) can have an unfortunate side effect of anorgasmia. It is really unacceptable, but if Zoloft (sertraline) is helping, it is hard to give it up. It is a common practice among psychiatrists to prescribe a medicine to counteract that side effect, and buproprion is often a first choice. It is a safe combination, although the dose may have to be optimized. Experience says it often works. Good luck! ...Read more

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I'm on Zoloft (sertraline) and vistaril can that cause women not to orgasm?

I'm on Zoloft (sertraline) and vistaril can that cause women not to orgasm?

Possibly: Zoloft (sertraline) and others in its class (ssri antidepressants) can interfere with sexual functioning, including delayed orgasm. I have known some for whom orgasm became impossible with these medicines, and it may be a dose-related effect. Talk with your doctor about it; there are ways to adjust things or add other medicines that may be able to normalize this. ...Read more

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I am 28 yrs old I have been married for 7 years have to kids and have never orgasmed, I am taking zoloft! wham can I take to help me climax, help!

I am 28 yrs old I have been married for 7 years have to kids and have never orgasmed, I am taking zoloft! wham can I take to help me climax, help!

Several roads: Yes, zoloft, (sertraline) an ssri may causeyour problem. Check with your physician to see if you can use bupropion [wellbutrin]. If this change does not correct the issue then you ask for a referral to a sexual dysfunction group. . My bias would be for you to call loyola medical center, in chicago and ask for dr renshaw's clinic. See if they have someone in your area who has trained with her. ...Read more

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Celexa causes hard to reach orgasm. Would lowering the dose help and can it become permanent? Im on 20 mg. It does help me though. Zoloft (sertraline) made me sick

Celexa causes hard to reach orgasm. Would lowering the dose help and can it become permanent? Im on 20 mg. It does help me though. Zoloft (sertraline) made me sick

Almost immedicately: The side effect is dose related and improves as soon as the blood levels drop which could be the next day. Of course over time if the depression returns your libido could plummet. Lexapro (escitalopram) may have less sexual dysfunction than Celexa. Young men who are anorgasmic on low doses of SSRI, I wonder about Bipolar disorder and would consider Lamictal as alternate rx ...Read more

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Im on my third day of Zoloft (sertraline) and I can't maintain erection and reach orgasm how long will it last and will it last forever? Im 22 and also on lorezepam

Im on my third day of Zoloft (sertraline) and I can't maintain erection and reach orgasm how long will it last and will it last forever? Im 22 and also on lorezepam

Common side effect: Prolonged time to orgasm us a common side effect of zoloft (sertraline) and all ssri drugs. It tends to be dose dependent. See your dr about reducing the dose. ...Read more

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My 33 y/o wife of 9 years has never had an orgasm from sex or toys/self.Her obgyn says she is ok physically.Psych says maybe anxiety - she has taken Zoloft (sertraline) for this in the past. What can we do?

My 33 y/o wife of 9 years has never had an orgasm from sex or toys/self.Her obgyn says she is ok physically.Psych says maybe anxiety - she has taken Zoloft (sertraline) for this in the past. What can we do?

Sexual fears: Many women have histories of rape or childhood abuse. I don't know whether this is the case with your wife, but if so, zoloft (sertraline) will not cure it. For some such women, sexual activity is so frightening that they can't explore/enjoy their own bodies' responses. If your wife regards your listed concerns as a problem, she could consult with a sensitive therapist. Healing will be a gradual process. ...Read more

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My fiancee has a history of depression and is on celexa, zoloft, Abilify and stratera. He sleeps too much, is always tired, has trouble focusing or remembering, has almost no sexual desire, can't get an erection without cialis, and can't reach orgasm wit

My fiancee has a history of depression and is on celexa, zoloft, Abilify and stratera.  He sleeps too much, is always tired, has trouble focusing or remembering, has almost no sexual desire, can't get an erection without cialis, and can't reach orgasm wit

Medication reeval: Your husband is on two antidepressants, abilify (aripiprazole) which is closer to the atypical antipsychotic class and stratera which is chemically very similar to an antidepressant. I would suggest it is time to reevaluate his medications and perhaps get a second opinion. ...Read more

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Sometimes when i masturbate i will orgasim fine and other times i will not orgasim at all and my penis will become limp i do take zoloft 100mg ?

Sometimes when i masturbate i will orgasim fine and other times i will not orgasim at all and my penis will become limp i do take zoloft 100mg ?

Erectile dysfunction: A number of things can explain your condition so I suggest you get checked out. Antidepressants can certainly cause weak erections/orgasms but so can things like poor sleep, stress and other health conditions. ...Read more

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I've been taking 50mg of sertraline for the last four weeks for anxiety and depression and i find it difficult orgasming will this effect wear off?

It may not: Ssris of which zoloft (sertraline) is one, can interfere with sexual arousal. Often it does not get better with time and the only "cure"can be discontinuing the medication. ...Read more

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Safe to take Zoloft with Skelaxin?

Safe to take Zoloft with Skelaxin?

Since they: both have widely different mechanisms of action it is probably OK but I would ALWAYS (Dr Z's Rule") check with the Prescribing Health Professional!!!!!

Hope this helps

Dr Z ...Read more

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Will Zoloft (sertraline) help me sleep?

Will Zoloft (sertraline) help me sleep?

No: At least in my clinical experience it is rarely if ever sedating. Having said that however, once it takes care of your anxiety or depression then your sleep may normalize. It is simply not a sedative hypnotic medication that can be used as needed. Best wishes. ...Read more

Dr. Heidi Fowler
1,086 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


Dr. Heidi Fowler
1,040 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more