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Doctor insights on: Zoloft And Fatigue

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Are Zoloft (sertraline) fatigue symtoms temporary?

Are Zoloft (sertraline) fatigue symtoms temporary?

FATIGUE EVAL: Normally will resolve as Zoloft (sertraline) doseAdjustment. If not you need full EXAM AND labs. CBC/CMP/B12/FOLATE /TFTS/VITD/CRP//SED RATE//IRON STUDIES/LYME TITERS. Start a. Gluten free diet Wholeapproach.com gutbliss.com. And high potency vitamins. Rejuvenation-science.com Then review results if no firm diagnosis is made, a sleep study may be necessary many subtle sleep disorders cause Fatigue ...Read more

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Dr. Donald Jacobson
1,041 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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I take lithium 1200mg, Buspar (buspirone) 60mg, propranolol 60mg per day. We recently added 25 mg per day of Zoloft and got fatigue and jitteriness. Worried.

I take lithium 1200mg, Buspar (buspirone) 60mg, propranolol 60mg per day. We recently added 25 mg per day of Zoloft and got fatigue and jitteriness. Worried.

Polypharmacy: Four psychotropic medications are quite a lot. In some cases, this many meds are required but in general it is best to try and achieve the same results with as few meds as possible. Increasing the amount of cognitive behavioral therapy is one way to increase the effectiveness of medications. Propranolol can cause depression and may be increasing your need for antidepressant medication. ...Read more

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I'm on my 3rd day of 25mg Zoloft (sertraline) for ptsd and ocd. Morning dosing and feel so tired by afternoon. Can Zoloft (sertraline) cause this fatigue?

I'm on my 3rd day of 25mg Zoloft (sertraline) for ptsd and ocd. Morning dosing and feel so tired by afternoon. Can Zoloft (sertraline) cause this fatigue?

Zoloft (sertraline) side effect: Zoloft (sertraline) doesn't always cause fatigue, but it is possible. Some people take Zoloft (sertraline) at bedtime, but it would be best to discuss this change in timing with your prescriber. Also, often the side effects that people have from Zoloft (sertraline) and other antidepressants resolve after the first 5-7 days on the medication, as your body adjusts to the medication, so keep this in mind as well. ...Read more

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Does Zoloft (sertraline) and buspirone cause fatigue?

No: In my practice, with my patients, I have not seen a patient with fatigue caused by either zoloft (sertraline) or buspirone, either along or together. If you are taking them for depression and anxiety, fatigue may be caused from either underlying condition. Please consult with your treating physician. ...Read more

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Which medication is more known for less fatigue, Zoloft (sertraline) or celexa? (it's for gad)

Which medication is more known for less fatigue, Zoloft (sertraline) or celexa? (it's for gad)

Fatigue from SSRI: It depends on the person. I have had patients complain of some sedation on both, depending on the dose, and also some anxiety from both. All in all, from my experience, i would say Celexa has slight more sedative effect than zoloft (sertraline). ...Read more

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I am constantly tired on zoloft (sertraline). I currently take it in the morning, is it possible if i switch to take it at night this will help with fatigue?

I am constantly tired on zoloft (sertraline). I currently take it in the morning, is it possible if i switch to take it at night this will help with fatigue?

It could: If zoloft (sertraline) makes you sleepy or fatigued, taking it at night may decrease this effect. Tiredness and fatigue can also be symptoms of depression, though. Not knowing how you were before beginning the medication, it's hard to know which is happening (ongoing depression or side effects from zoloft (sertraline)). Best to speak with your physician so s/he can advise you better. ...Read more

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I've been on Zoloft (sertraline) for 6 months and lamotrigine for 2 - I am constantly fatigued - is this a normal side effect? Can i expect this to pass?

I've been on Zoloft (sertraline) for 6 months and lamotrigine for 2 - I am constantly fatigued - is this a normal side effect? Can i expect this to pass?

Probably, depends...: Fatigue could be a symptom of many medical conditions including mood disorder for which i suppose the medications were prescribed. If the fatigue started as a side effect of the medications, changing the dosing time may help assuming there are no other medical issues like anemia et.C going on. A simple blood test may help in the latter case. Good luck. ...Read more

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On Zoloft (sertraline) - I won't sleep for days without fatigue or drowsiness? I know I need to sleep, I didn't have this problem before Zoloft (sertraline)

On Zoloft (sertraline) - I won't sleep for days without fatigue or drowsiness? I know I need to sleep, I didn't have this problem before Zoloft (sertraline)

Very Important !: Excessive energy and lack of sleep could be side effects of Zoloft (sertraline). It can sometimes trigger hypomania that presents as these symptoms. Immediately contact your psychiatrist or whoever has prescribed this medicine. It is important. ...Read more

Dr. Alan Ali
993 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more


Dr. Michael Rothman
1,268 doctors shared insights

Lethargy (Definition)

Lack of energy, ...Read more