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Doctor insights on: Zoloft Allergic Reaction

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I've been taking Zoloft (sertraline) for about 2 months and now I'm getting red welts almost everyday in a different location. I'm thinking allergic reaction.

I've been taking Zoloft (sertraline) for about 2 months and now I'm getting red welts almost everyday in a different location. I'm thinking allergic reaction.

Think Call to Dr!: This is a definite reason to tell your Dr ASAP. Don't just stop since it might be necessary to cover you for bad w/drawal issues. The Dr needs to know! If the symptoms worsen before you can see the Dr - go to an ER. You thought right! I'm glad you asked. Call now! ...Read more

Dr. John Chiu
2,630 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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I've had an allergic reaction (skin rash) to a dose increase of sertraline. The rash is on my face, neck, chest, back and arms. I took a full 25 mg dose 1x and woke up with a slight rash on my face. Took a 2nd 25 mg dose and the rash is now everywhere

I've had an allergic reaction (skin rash) to a dose increase of sertraline. The rash is on my face, neck, chest, back and arms. I took a full 25 mg dose 1x and woke up with a slight rash on my face. Took a 2nd 25 mg dose and the rash is now everywhere

See MD: Contact your prescribing doctor without delay for advice. Rash from sertraline has been reported, but is not common. Doctor needs to see your rash and advise. If you can't reach your doctor, go to urgent care or ED for proper diagnosis and guidance. Hope you feel better soon. ...Read more

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Is it possible to develop allergies or other side effects from switching from brand name Zoloft (sertraline) to generic Sertraline?

Is it possible to develop allergies or other side effects from switching from brand name Zoloft (sertraline) to generic Sertraline?

Not likely: Don't worry about that change. The inspection quality is not significantly different in any licensed pharmaceutical lab. Really, don't worry. That could cause an experience of negative effects for no other reason. It's a true phenomena - expectancy is powerful. Avoid it. ...Read more

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I am taking 3 different meds for allergies and zoloft (sertraline). I had a blood test and skin test without stopping them. Did that negate the tests?

I am taking 3 different meds for allergies and zoloft (sertraline). I had a blood test and skin test without stopping them. Did that negate the tests?

Maybe: If you had a positive response to the allergy test, it is probably valid. However, the medications could have interfered with the test to give you a negative result when you are really allergic to something. There are different types of response to an allergen that is often cell-mediated but the process is rather complicated. There have been reported interference due to use of medications. ...Read more

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Feeling similar to "brain zap" - minor allergies with mild congestion in head - 50mg zoloft/day - could either be the cause? Concerned!

Feeling similar to "brain zap" - minor allergies with mild congestion in head - 50mg zoloft/day - could either be the cause? Concerned!

Yep.: Either could be - or both. Many questions like: for how long, previous times - same symptoms?
What else are you taking? Etc.
I thinkyou want your dr to check this out. ...Read more

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I am having a metallic taste in my mouth and a worsening"hacking/phlegm" cough. In case its relevant, I am also taking Zoloft (sertraline) and Claritin for allergies. What should I do?

I am having a metallic taste in my mouth and a worsening"hacking/phlegm" cough. In case its relevant, I am also taking Zoloft (sertraline) and Claritin for allergies. What should I do?

Probably phelgm: Mucous secretion due to that produced in the upper sinus passages and upper airway as well at that produced in the lower respiratory tree can drain into the back of the mouth and when tasted, can have a metallic taste pending the type of infection, some blood and if mixed with medications, food and other ingestants, give the metallic taste. If this doesn't clear with "wellness" get checked out. ...Read more

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19 year-old college student with a 2-month history of involuntary episodes of falling asleep.....?

19 year-old college student with a 2-month history of involuntary episodes of falling asleep.....?

Narcolepsy requires: A comprehensive medical history, + physical & neurological exams to diagnose. A polysomnogram (overnight sleep study) & a daytime multiple sleep latency test are needed to diagnose sleep apnea. Other causes & tests for them are on www. Ninds. Nih. Gov/disorders/narcolepsy/detail_narcolepsy. Htm. See your primary MD for evaluation & referrals for needed studies & specialists. ...Read more

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I have an anaphylactic reaction to zoloft (sertraline). What other things could I be allergic to?

I have an anaphylactic reaction to zoloft (sertraline). What other things could I be allergic to?

Zoloft (sertraline) allergy: Best to have skin patch allergy test. See an allergist or your pcp for referral. ...Read more

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At what maximum rate do allergic reactions to Zoloft (sertraline) happen?

Depends: Most likely what you are describing is an intolerance or idiosyncratic reaction (unexpected reaction particular to a small number of people likely genetically determined). You will need to provide a more detailed description of your reactions in addition to the time of onset after taking the pill for us to give you an opinion. ...Read more

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Bad reaction with Zoloft (sertraline) weaned down to 12.5 nine days ago side effects were present 4 days after should I half it again or wait another week?

Bad reaction with Zoloft (sertraline) weaned down to 12.5 nine days ago side effects were present 4 days after should I half it again or wait another week?

Zoloft (sertraline): It is really important that you wean off medications under the supervision of the doctor who prescribed it. I have not dropped to a dose lower than 12.5 mg w patients - but it depends on your providers' directives. ...Read more

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Is there an adverse reaction between losartan and zoloft (sertraline)?

Is there an adverse reaction between losartan and zoloft (sertraline)?

One adverse symptom: Is muscle pain. Perhaps not taking both meds at the same time may help. Check out this link. Http://www. Ehealthme. Com/drug-interactions-side-effects/losartan-hctz-sertraline-hydro-7379307. ...Read more

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My husband currently takes Zoloft, (sertraline) and has come down with a nasty cold. Stuffy nose etc. What OTC can he take that will not have an adverse reaction?

My husband currently takes Zoloft, (sertraline) and has come down with a nasty cold. Stuffy nose etc. What OTC can he take that will not have an adverse reaction?

Taking psych: Medicine shouldn't interfere with overcoming a cold- Ask your doctor or pharmacist to recommend something. Drink fluids, rest and make sure he is eating enough fruits/veggies for proper elimination. ...Read more

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Abdominal pain for solid 56 hours. ER didn't know what caused it. I thought it was a reaction to Zoloft (sertraline). Bentyl hasn't helped much. Advice?

Abdominal pain for solid 56 hours. ER didn't know what caused it. I thought it was a reaction to Zoloft (sertraline). Bentyl hasn't helped much. Advice?

Acute Abdominal pain: I understand your distress.
Bentyl is used to relieve spasms of the muscles in the stomach and intestines.
Due to continued Abdominal pain for 56 hours, go to ER and see Gastroenterologist for diagnosis of Gastritis due to H. Pylori, use of Aspirin, NSAID, Stress, Alcohol use, Pernicious anemia, Bile reflux, or Infections caused by bacteria and viruses; Treatment.
See Psychiatrist for Therapy ...Read more

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On Buspar (buspirone) 5 mg for 2 weeks, 10 mg for 1 week. Think I'm getting hives? Itchy, small bumps hard to see. Had severe reaction to Zoloft but no hives.

On Buspar (buspirone) 5 mg for 2 weeks, 10 mg for 1 week. Think I'm getting hives? Itchy, small bumps hard to see. Had severe reaction to Zoloft but no hives.

Prob not hives: hives are usually neither small nor hard, though they are itchy. They are generally large and soft, even fluctuant (give way when you push on them and have fluid in them). If you think you are having an allergic response to them, STOP taking them and call the prescriber and/or talk to your pharmacist. Someone has to see these to make a diagnosis. ...Read more

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Is it dangerous to take Zoloft (sertraline) if you are allergic to sulfa drugs?

Is it dangerous to take Zoloft (sertraline) if you are allergic to sulfa drugs?

It Is Safe: Zoloft (sertraline) does not contain any sulfa in its tablets. There are generic versions of zoloft and they are also sulfa free. Zoloft is a serotonin reuptake inhibitor medication that has been approved by the fda for the following conditions: major depressive disorder, obsessive compulsive disorder, panic disorder, social phobia, post-traumatic stress disorder, premenstual dysphoric disorder. ...Read more

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I'm having bad reactions to 50mg Zoloft (sertraline). Dr said stop and referred me to someone else. Can I stop for 2 days until I talk with another Dr?

I'm having bad reactions to 50mg Zoloft (sertraline). Dr said stop and referred me to someone else. Can I stop for 2 days until I talk with another Dr?

How long taken?: If you've been taking it for more than a few weeks, it might be wise to halve the dose for these two days to avoid w/drawal. Especially if you cold turkey and feel anything really bad - take 25mg then. Plan w/ the new Dr ahead about what to do if you're not pleased w/ a Rx. Also consider CBT therapy - no side effects and w/ meds it can reduce dose need. Best! ...Read more

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My doc gave me duromine although I'm on Zoloft (sertraline) too but was told by someone else not to mix them. I have not have any bad reactions and feel amazing?

My doc gave me duromine although I'm on Zoloft (sertraline) too but was told by someone else not to mix them. I have not have any bad reactions and feel amazing?

Yes drug interreact: Good part you 'feel amazing', it is known to cause drug inter reaction, potentiates the effects on autonomic system. In you condition it good to feel amazingly good but you have to bring to the attention of your doctor, that you are on zoloft (sertraline), then decide to continue under observation or to discontinue duromine (you need zoloft (sertraline)) switch to some thing else ...Read more

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Never been allergic to Zoloft (sertraline) and lamictal, which I am using now.!! What is the chances that I will become allergic to them now? Is this just anxiety?

Never been allergic to Zoloft (sertraline) and lamictal, which I am using now.!! What is the chances that I will become allergic to them now? Is this just anxiety?

May need further eva: If you developed a rash recently, this needs to be evaluated further. Lamictal, in particular, may need to be discontinued. The fact that you did not have a rash before while on Lamictal does not preclude the possibility that you have developed a reaction to it. ...Read more

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Can I take zoloft, (sertraline) stribild, and tramadol together without any adverse reactions?

Interactions: Several interactions are reported with these drugs, some potentially dangerous. Best to talk to your doctor about use of other medications with Stribild. ...Read more

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Hi. I have a fear og becoming allergic to Zoloft (sertraline) and lamictal. Been using them for over 1 year, and im not allergic to them. Do I need to worry?

Hi. I have a fear og becoming allergic to Zoloft (sertraline) and lamictal. Been using them for over 1 year, and im not allergic to them. Do I need to worry?

Chronic anxiety: This is just unfounded anxiety but is why these meds were prescribed in the first place. I hope you are seeing a mental health professional to work through these issues. ...Read more

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If you have tolerated Zoloft (sertraline) & Lamictal for over a year. Then it's unlikely to suddenly become allergic to them? I'm asking because of health anxiety.

If you have tolerated Zoloft (sertraline) & Lamictal for over a year. Then it's unlikely to suddenly become allergic to them? I'm asking because of health anxiety.

Probably not specify: There have been cases of delayed hypersensitivity to Lamictal, however, to the best of my knowledge it would not occur years after being stable on both meds. Are you saying that you have a health anxiety that you think is allergic in nature? Or are you experiencing specific allergic reaction symptoms- if so what are they? ...Read more

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Can you suddenly become allergic to Zoloft (sertraline) and Lamictal? I'm not allergic to them. Yet I'm afraid this will happen. Is this irrational fear? Fobia?

Sensitivities: While it is possible to develop an allergic reaction to any number of substances, sensitivities and side effects to these medications are certainly possible. Close supervision by the prescribing health care provider is needed. ...Read more

Dr. James Lin Dr. Lin
1 doctor agreed:
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I'm happy wellbutrin (bupropion) it really reversed the Zoloft sexual problem as erection and libido do that result well stay permanent?

Dr. James Lin Dr. Lin
1 doctor agreed:
I'm happy wellbutrin (bupropion) it really reversed the Zoloft sexual problem as erection and libido do that result well stay permanent?

Wait. ..: Two-day use may not be long enough to see result from Wellbutrin (bupropion) yet. So, give additional 7 days and see. If not improving or evolving as planned/expected, report your condition to the treating Doc so to decide / adjust for what you need. Besides taking all such drugs, don't forget practicing low-risk healthy lifestyle without overindulgence is the foundation of healthcare & the ke ...Read more

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Can you suddenly become allergic to Zoloft (sertraline) and Lamictal? I'm not allergic to them. Yet I'm afraid it will make my tongue and throath swell. Anxiety?

Fear of allergy: To be clear, you're saying you suffer from anxiety, hypochondriasis, and that you are not currently having any allergy/physical symptoms? It sounds like you are having sxs of hypochondriasis and anxiety = fear that you will develop a sudden allergy to your meds. As you've no physical symptoms at all now, risk of hypersensitivity is quite low. ...Read more

Dr. John Chiu
1,043 Doctors shared insights

Allergic Reaction (Definition)

Sensitivities to substances, called allergens, that come into contact with the skin, nose, eyes, respiratory tract, and gastrointestinal tract. They can be inhaled into the ...Read more


Dr. Heidi Fowler
1,087 Doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more