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Doctor insights on: Zoladex Injection Side Effects

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Is there anything I can do to decrease side effects for zoladex (goserelin) or make them more manageable? Add back therapy will be used.

So many SEs: Zoladex (goserelin) is associated with so many potential ses it is difficult to know how to answer this generic question. Who prescribed it for you and why? Please ask them to help you. ...Read more

Dr. Janice Alexander
51 Doctors shared insights

Goserelin (Definition)

Goserelin is an anti-prostate cancer agent which is a ...Read more


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Oncologist recommends zoladex (goserelin) to be injected, given the side effects, is it worth it?

Oncologist recommends zoladex (goserelin) to be injected, given the side effects, is it worth it?

Yes: This assumes the reasons for advising the medicine are valid. With that in mind the answer is yes, overwhelmingly. Also, there are no "side effects" to zoladex (goserelin), (goserelin) only "effects". The goal of zoladex (goserelin) is to lower testosterone levels. Low levels result in a predictable set of issues over time. Side effects (unexpected problems) do not happen w/ zoladex (goserelin). Only the expected! ...Read more

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I'm on zoladex (goserelin) medicin because of breast can. Plz. I want to know about it's side effects?

I'm on zoladex (goserelin) medicin because of breast can. Plz. I want to know about it's side effects?

There'r many of them: I will list from most common to least: flushing, vaginitis, hot flashes, reduced libido, mood swings, depression (more in women), sweating, acne, diarrhea, breast atrophy, headaches (more in women), seborrhea, tumor flare, sexual dysfunctions, leg swelling, pain, nausea, lethargy, rash, heart/lungs troubles, strokes, kid impairment, high calcium, cystitis etc. U may get some, or none. Good luck. ...Read more

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How long does it take for zoladex (goserelin) injection to work IV had it 10 days ago and still in pain with cyst on ovaries?

How long does it take for zoladex (goserelin) injection to work IV had it 10 days ago and still in pain with cyst on ovaries?

IV ZOLADEX (goserelin)???: I do not think that zoladex (goserelin) IV is a currently used treatment for a painful ovarian cyst. Without details as to size and an ultrasound exam showing the cyst's characteristics, I cannot recommend treatment. A painful clear ovarian cyst can be aspirated with ultrasound transvaginal guidance and the pain should go away within a few hours, if not sooner. Hope this info helps! ...Read more

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I'm worried that I may be pregnant, I had a zoladex (goserelin) injection in november 10, 8mg, but I still haven't started bleeding, could it be possible.

I'm worried that I may be pregnant, I had a zoladex (goserelin) injection in november 10, 8mg, but I still haven't started bleeding, could it be possible.

Take a test: If you're worried that you may be pregnant, take a home pregnancy test. They are fast and effective and accurate and will give you the information that you are seeking. ...Read more

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My daughter had a pituitary gland disorder as a child which resulted in a precocious puberty. .. She stopped her zoladex injections at twelve and she is now 21. .. For the past 6 years she has suffered form acute anxiety and panic lasting for days there h

My daughter had a pituitary gland disorder as a child which resulted in a precocious puberty. .. She stopped her zoladex injections at twelve and she is now 21. .. For the past 6 years she has suffered form acute anxiety and panic lasting for days there h

Anxiety DO: There is no reason the precocious puberty and zoladex (goserelin) treatment are directly related to anxiety, at least as a pharmacologic (drug) effect. It's possible that her experience and worries from that time are affecting her, it also may be unrelated. Evaluate with a counsellor or a good primary doctor for panic/anxiety do, and best of luck. ...Read more

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Just started a course of zoladex, (goserelin) what is a side effect?

Just started a course of zoladex, (goserelin) what is a side effect?

Ask your doctor: Www. Drugs. Com is a great website to get your question answered thoroughly. Also ask your doctor....Many times the inserts and web info is over the top complete and can be a bit scary. Ask your doc if he/she is having any side effect issues with other patients or what symptoms would be a concern. ...Read more

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I'm in zoladex (goserelin) had my 1st one 28 days ago about to have the 2nd one I have no side affects I'm on this cause I have cysts that bust I'm still in pain?

I'm in zoladex (goserelin) had my 1st one 28 days ago about to have the 2nd one I have no side affects I'm on this cause I have cysts that bust I'm still in pain?

The pain is from: Irritation of the lining of your pelvic and abdominal area. You may take otc nsaids and ask your dr if he would consider prescribing you opioids for severe pain. Bless u! ...Read more

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Have just had my first dose of zoladex (goserelin) to prepare my womb. What could be a side effect?

Have just had my first dose of zoladex (goserelin) to prepare my womb. What could be a side effect?

Many Things: Hot flashes (flushing), dizziness, headache, increased sweating, decreased sexual interest/ability, trouble sleeping, nausea, change in breast size, hair loss, or mental/mood changes (such as depression, mood swings, hallucinations) may occur. Pain, bruising, bleeding, redness, or swelling at the injection site may also occur. Vaginal dryness may also occur. ...Read more

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What is the use of zoladex (goserelin)?

What is the use of zoladex (goserelin)?

Hormone regulation: This agent is a gonadatropin releasing hormone agonist. It interferes with feedback loops that control hormone balance, it stops some hormone production.
It is used in breast cancer, prostate cancer, endometriosis and fibroids to name a few. ...Read more

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I'm using zoladex (goserelin) 10.8mg, but when I search about zoladex (goserelin) it says "the 10.8-milligram syringe should not be used in  women" why?

I'm using zoladex (goserelin) 10.8mg, but when I search about zoladex (goserelin) it says "the 10.8-milligram syringe should not be used in  women" why?

Clarify dose: Zoladex (goserelin) at that dose is usually used for prostate cancer in men. It can sometimes be used for breast cancer, endometriosis and other gynecologic disorders. Simply confirm with your doctor the dose you are supposed to be taking. ...Read more

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Can I get pregnant on zoladex (goserelin)?

Can I get pregnant on zoladex (goserelin)?

No!: Zoladex (goserelin) is pregnancy category x, which means there is positive evidence of harm to the fetus in women who are taking it. ...Read more

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How soon after comming of zoladex (goserelin) can I concieve?

How soon after comming of zoladex (goserelin) can I concieve?

That depends: Depends on why you were on zoladex, (goserelin) how long on zoladex, (goserelin) and your age. The older you are and the greater the duration of therapy the longer it will take for your menses to resume normally. ...Read more

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How long does it take for a woman to have her periods back after taking zoladex (goserelin)?

How long does it take for a woman to have her periods back after taking zoladex (goserelin)?

Depends: Zoladex (goserelin) comes in 3.6 & 10.8 mg implants. The lower dose is designed to supress gonadotropin release (medical menopause) for 28 days. The higher dose for approx 3 months. Usually, you'll resume cycles 1 & 3 months respectively although there can be a 2-4 week lag depending on your age, ovulation patterns, and proximity to menopause. Remember it's not birth control and this is needed. ...Read more

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What effect does zoladex (goserelin) have on thyroid?

What effect does zoladex (goserelin) have on thyroid?

None: That I have seen. It does not impair TSH (thyroid stimulating hormone) only lh/icsh - the provker of the testis to generate testosterone. ...Read more

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What does zoladex (goserelin) do for cancer patients?

What does zoladex (goserelin) do for cancer patients?

Zoladex (goserelin): Zoladex (goserelin) is helpful for treatment of prostate cancer in men and breast cancer in women.

I am sorry if you have one of these conditions and wish you well.

If you are on Zoladex (goserelin) please have your doctor to give you all the information available.

You can also look up Zoladex (goserelin) on the web. ...Read more

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Is 133.5pmol/l for estrogen and 1.31nmol/l for progesterone low or high if I've been on zoladex (goserelin) for 7 mth?

Is 133.5pmol/l for estrogen and 1.31nmol/l for progesterone low or high if I've been on zoladex (goserelin) for 7 mth?

See answer: Depends on the reason you are on Zoladex (goserelin)...If it is Endometriosis, then your pain should have resolved or if you are on it for bleeding then bleeding should have resolved. Bottom line is it shouldn't matter what your Estradiol and Progesterone are, although your ovaries are suppressed by the levels you posted and your medication is working. Hope this helps. ...Read more

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Is zoladex (goserelin) effective for breast cancer?

Is zoladex (goserelin) effective for breast cancer?

Depends: Your physician may offer this as one of a variety of possible hormonal manipulations if and only if the pathology team says the tumor is hormone-sensitive. When it works, it is often strikingly successful. ...Read more

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Just got a shot of zoladex (goserelin) that should last for 3months, when can I have laproscopy to remove fibroids? Thanks

Just got a shot of zoladex (goserelin) that should last for 3months, when can I have laproscopy to remove fibroids? Thanks

Ask your gynecologis: I am sure he/she has given you some instructions. Just follow them. I do not think there is any hard and fast rule here. I even wonder about why she gave you a zoladex (goserelin) shot? ...Read more

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I am suffering of endometriosys for 4 Years now. I heard about the Visanne treatment. I had zoladex (goserelin) after my surgery in 2011 and it didn't work.

I am suffering of endometriosys for 4 Years now. I heard about the Visanne treatment. I had zoladex (goserelin) after my surgery in 2011 and it didn't work.

Not approved: Visanne is still undergoing clinical trials for relief of pain due to endometriosis and has not yet been approved by the FDA. Large trials are on going and have shown some significant benefit. I am not sure about access to it in Italy but it sounds very promising. Hope this helps. ...Read more

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Can zoladex (goserelin) affect the accuracy of a pregnancy test result?

Can zoladex (goserelin) affect the accuracy of a pregnancy test result?

May be: You should be using birth control if on this drug. See the site below for more information, http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0000011/. ...Read more

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What link, if any, is there between zoladex (goserelin) and high blood pressure?

What link, if any, is there between zoladex (goserelin) and high blood pressure?

Possible: This is an uncommon effect of the drug seen in 1-5% of patients on the original studies. There can be other causes of increased blood pressure from the hormonal side effects as well.
It is a good idea to meet with your family doctor to discuss treatment of the blood pressure. In many cases stopping zoladex (goserelin) might not be easy to stop. ...Read more

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My wife had an endometriosis due to chocolate csyst then 3 months of zoladex (goserelin) 3.5 mg medication. How are the chances f having a healthy pregnancy.

Patent Tubes?: Hard to counsel your chances without all the information available. One thing to consider though is that endometriosis to the degree that leads to a cyst requiring surgical removal may sometimes affect the tubes, which if they're not open, then your chances are 0%. Hysterosalpingogram is a study that injects dye through the cervix to determine if the tubes are open. ...Read more

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Can a zoladex (goserelin) 3.6mg implant induce artificial menopause?

Can a zoladex (goserelin) 3.6mg implant induce artificial menopause?

Chemical menopause: Zoladex (goserelin) 3.6 mg implanted every 28 days will put a woman chemically into menopause and make her menstrual periods stop. In fact, about 2 weeks after the first implant there will be a hormone withdrawal bleeding, after the next implant there will be no bleeding, if the medication works perfectly. ...Read more

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My doc wants me to take zoladex (goserelin) for my endemetriosis is it a good idea to do this treatment?

There are sev. Issue: Been confirmed by laparoscopy? How severe is process? How severe is the pain? Zoladex puts you into temporary menopause and will temporarily decrease amount secondary to less hormones but is expensive w/side effects, I rec. Low dose add back hormone for hot flashes. Contraceptive pills first line treatment. If pain, anxiety combo may benefit from med like Cymbalta (duloxetine) 30mg w/ocp, improve pain filter. ...Read more

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My husband zoladex (goserelin) inj but now doctors advise him to remove testis, is it safe for him in this age and is he cure by this surgery?

My husband zoladex (goserelin) inj but now doctors advise him to remove testis, is it safe for him in this age and is he cure by this surgery?

Safe, not curative: Zoladex (goserelin) is a drug which prevents the testicles from making testosterone, used to treat advanced prostate cancer. Prostate ca cells thrive in the presence of testosterone. Surgical removal of the testicles accomplishes the same purpose. Neither CURES metastatic prostate ca. Recent study suggests that patients with metastatic prostate ca do better with hormonal therapy + drug docetaxel. ...Read more

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I'm 18, my endometriosis reactivated, already had one surgery. One doctor wants to prescribe zoladex (goserelin) the other surgery. What should I choose?

Surgery: Endometriosis is a surgically treated disease. However the correct surgery is crucial. Excision of endo and not cautery or laser is the correct approach. Also important to rule out other causes of pain since endo is often not the direct cause of a woman's pain. You need to see someone who is highly experienced in endometriosis and pelvic pain. Good luck. ...Read more

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Recently had ultrasound which showed 31mm choc cyst and been put on 4 months of zoladex (goserelin) but should I be asking about surgery as doc didn't mention it?

Recently had ultrasound which showed 31mm choc cyst and been put on 4 months of zoladex (goserelin) but should I be asking about surgery as doc didn't mention it?

Yes: I think you should know all of your options. Of course, your cyst is small, and a lot of doctors won't operate for cysts that small. A lot depends on your plans for fertility, as endometriomas can prevent women who want to be pregnant from being able to become pregnant. I would ask for another appointment to discuss all your options with your doctor and make sure you agree with the plan. ...Read more

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Should men receiving zoladex (goserelin) for prostate cancer also be on some form of hrt?

Should men receiving zoladex (goserelin) for prostate cancer also be on some form of hrt?

Counterproductive: Zoladex (goserelin) eliminates all production of testosterone by the testes. Hormone replacement therapy would be counterproductive ...Read more

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Should men receiving zoladex (goserelin) for prostate cancer be on some form of HRT as well?

Should men receiving zoladex (goserelin) for prostate cancer be on some form of HRT as well?

Hormones: Prostate cancer growth is slowed down by meds like that to reduce testosterone. You wouldn't want to take testosterone, it makes the cancer grow! Good multi vitamin and calcium are good ideas when on testosterone suppression for pca. ...Read more

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Taking tamoxifen and zoladex (goserelin). No period for 4 years had 3 polyps removed 6 weeks ago still bleeding?

Taking tamoxifen and zoladex (goserelin). No period for 4 years had 3 polyps removed 6 weeks ago still bleeding?

Endometrial bleeding: As long as your polyps and your endometrial Biopsy were negative for cancer of the uterus, the bleeding will probably stop soon. Check with your GYN.
Check with your Oncologist to see if your are going back on Tamoxifen
Take care ...Read more

Dr. Jan Lei Iwata
49 Doctors shared insights

Zoladex (Definition)

Zoladex is an anti-prostate cancer agent which is a ...Read more


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