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Doctor insights on: Zofran Medications

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Does the drug Zofran (ondansetron) have withdrawal symptoms?

Does the drug Zofran (ondansetron) have withdrawal symptoms?

NO: Zofran (ondansetron) is an antiemetic. Whatever sedation you may experience that you may think is an "addiction problem" is not. Withdrawl occurs after long periods of drugs with such addictive properties which are abruptly stopped. ...Read more

Dr. James Henning
403 doctors shared insights

Ondansetron (Definition)

Ondansetron is a nausea and vomiting agent which is a ...Read more


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If Zofran (ondansetron) caused QTc prolongation, would QT int. go back to normal after stopping the medication? Or is this a permanent change?

If Zofran (ondansetron) caused QTc prolongation, would QT int. go back to normal after stopping the medication? Or is this a permanent change?

BACK TO NORMAL: Ondansetron (Zofran) primarily blocks potassium channels, prolonging the QT interval, but these changes are acute, transient and reversible. Concern was for IV formulation in doses higher than 16 mg. ...Read more

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Theoretical question- can you drink the medication from an ampoule of Zofran (ondansetron) instead of injecting it and it will still be effective?

Theoretical question- can you drink the medication from an ampoule of Zofran (ondansetron) instead of injecting it and it will still be effective?

No: It is not intendec for oral use. The formulation not to be specific tends to be altered by gastric ph etc. Oral preps are researched to work specifically. ...Read more

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Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Other biologic.: The details of your child's history and past treatments are unknown, of course, but one could consider an alternative biologic. Each one is designed differently than others. I urge to set up a follow up with your child's pediatric rheumatologist to discuss further. Good luck and hope they feel better. ...Read more

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Does zofran (ondansetron) stop/prevent all nausea? I.e. reflux, medications, virus, etc.

Does zofran (ondansetron) stop/prevent all nausea? I.e. reflux, medications, virus, etc.

Not really: It was originally used for vomiting induced by chemotherapy and anesthesia, but has become widely used for all types of vomiting including vomiting in pregnancy. No drug is 100% effective and failure rates in studies are as high as 25-30%. Thanks for trusting HealthTap! ...Read more

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Dr. Alan Ali Dr. Ali
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Are there any interactions of these medications? I take zofran, buspar, (buspirone) and xanax as needed.

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Are there any interactions of these medications? I take zofran, buspar, (buspirone) and xanax as needed.

Zofran/Buspar: Risk does exist when Zofran is taken with Buspar, (buspirone) due to raising the Serotonin (Serotonin syndrome), depending on the doses. Consult with your doctor. ...Read more

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Can an anti-nausea medication be added to my i.v. sedation line? Such as Zofran (ondansetron) to prevent the effects of the anesthesia?

Can an anti-nausea medication be added to my i.v. sedation line? Such as Zofran (ondansetron) to prevent the effects of the anesthesia?

Discuss with anesthe: siologist. This is their call. Based on your discussion they'll determine best what to use to make your procedure as comfortable as possible. ...Read more

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Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Ondansetron: Zofran (ondansetron) in doses greater than 16 mg at a time has been implicated in prolonging the qt interval. This effect would last for a few hours while the drug was in the system. A single 4 mg dose does not carry this risk. ...Read more

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Can emend be effective on its own for vomiting and nausea? I cant tolerate zofran (ondansetron) or zofran (ondansetron) class drugs.

Can emend be effective on its own for vomiting and nausea? I cant tolerate zofran (ondansetron) or zofran (ondansetron) class drugs.

Preventively only: Emend s effective when administered ahead of time to prevent the nausea and vomiting associated with chemotherapy but isn't effective after the fact. Emend has quite a number of side effects and interactions with other medications. You need to discuss this with your treating physician. ...Read more

Dr. Julie Abbott
310 doctors shared insights

Zofran (Definition)

Zofran is a nausea and vomiting agent which is a ...Read more