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Doctor insights on: Zofran Drug Interactions

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Can I take Zofran for nausea if I take Wellbutrin (bupropion) xl everyday for depression? I read online there was a major drug interaction.

Can I take Zofran for nausea if I take Wellbutrin (bupropion) xl everyday for depression? I read online there was a major drug interaction.

Drug interaction..: There is a drug interaction between Zofran (ondansetron) and Wellbtutrin called "serotonin syndrome." It means an excessive amount of serotonin in the brain. Can be quite serious. Please discuss with prescribing doctor. I hope this helps. Take care.

Dr. Bernard Seif
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Drug Interaction (Definition)

When the combination of two agents cause an effect, intended or unintended, that would not have otherwise ...Read more


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Drug interactions between ondansetron and metoprolol?

Drug interactions between ondansetron and metoprolol?

See below: There are no reported drug interactions between these 2 drugs. This doesn't mean that interactions does not exist. If you feel anything unusual contact your medical provider for further management.

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Does the drug Zofran (ondansetron) have withdrawal symptoms?

Does the drug Zofran (ondansetron) have withdrawal symptoms?

NO: Zofran (ondansetron) is an antiemetic. Whatever sedation you may experience that you may think is an "addiction problem" is not. Withdrawl occurs after long periods of drugs with such addictive properties which are abruptly stopped.

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Can I take esomeprazole and Zofran (ondansetron) at the same time? Will it cause the zofran (ondansetron) not to work? Or are there no interactions?

Can I take esomeprazole and Zofran (ondansetron) at the same time? Will it cause the zofran (ondansetron) not to work? Or are there no interactions?

Drug interactions: On review of the literature, there are no interactions that I could find between the two medications. To be on the safe side, space out the timing when taking each medication. If you do have any problems, let us know, but the likelihood of interactions occurring is low. Hope this helps & ask, if you have any other questions.

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I took my lexapro (escitalopram) at 7:45 am and took zofran at 4pm. Not knowing their interactions. I am healthy with no health concerns. Will I be ok?

I took my lexapro (escitalopram) at 7:45 am and took zofran at 4pm. Not knowing their interactions. I am healthy with no health concerns. Will I be ok?

Medication effects: I commend you for good Health. Lexapro (escitalopram) is medication for depression. Zofran is for marked nausea and vomiting. Taking lexapro (escitalopram) after meals can decrease nausea. Using Zofran with Lexapro (escitalopram) can increase the risk of a rare but serious Serotonin Syndrome; and can increase the risk of an irregular heart rhythm that may be serious. See Psychiatrist for Medication interactions and Therapy

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Citalopram 20 mg at bed & Zofran (ondansetron) 8 mg twice a day, one in the morning and one in the afternoon. Should I worry about the "major" interactions.

Citalopram 20 mg at bed & Zofran (ondansetron) 8 mg twice a day, one in the morning and one in the afternoon. Should I worry about the "major" interactions.

Discuss w/ Dr: You've read enough to raise your concern - the best way to resolve it is by a good talk w/ the Dr. Be sure they know your worries and ask them to help you understand why this is a good treatment plan for you. If you then disagree, seek a 2nd opinion.

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I took butterbur and Zofran (ondansetron) for a migraine this am. Are there any harmful interactions?

I took butterbur and Zofran (ondansetron) for a migraine this am. Are there any harmful interactions?

Insufficient data: Butterbur is an herb and unfortunately there is insufficient evidence to rate effectiveness or check drug interaction. There are many traditional abortive medications that are fda approved with sufficient data of evidence based medicine. Rec. Consult with headache or orofacial pain specialist.

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Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Other biologic.: The details of your child's history and past treatments are unknown, of course, but one could consider an alternative biologic. Each one is designed differently than others. I urge to set up a follow up with your child's pediatric rheumatologist to discuss further. Good luck and hope they feel better.

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Can I take zofran (ondansetron) for nausea if I take 10mg prozac once a day? Are there any interactions?

Probably ok: Sometimes there is an interaction, but generally, these can be safely used together. Zofran can cause sleepiness, this is the primary side effect to be aware of.

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Dr. Alan Ali Dr. Ali
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Are there any interactions of these medications? I take zofran, buspar, (buspirone) and xanax as needed.

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Are there any interactions of these medications? I take zofran, buspar, (buspirone) and xanax as needed.

Zofran/Buspar: Risk does exist when Zofran is taken with Buspar, (buspirone) due to raising the Serotonin (Serotonin syndrome), depending on the doses. Consult with your doctor.

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Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (i took one dose) does the risk for cardiac issues cease?

Ondansetron: Zofran (ondansetron) in doses greater than 16 mg at a time has been implicated in prolonging the qt interval. This effect would last for a few hours while the drug was in the system. A single 4 mg dose does not carry this risk.

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Can emend be effective on its own for vomiting and nausea? I cant tolerate zofran (ondansetron) or zofran (ondansetron) class drugs.

Can emend be effective on its own for vomiting and nausea? I cant tolerate zofran (ondansetron) or zofran (ondansetron) class drugs.

Preventively only: Emend s effective when administered ahead of time to prevent the nausea and vomiting associated with chemotherapy but isn't effective after the fact. Emend has quite a number of side effects and interactions with other medications. You need to discuss this with your treating physician.

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I've taken Zofran, oral nasal decongestant, nasal spray (not Same ingredients) &.5 Ativan. Is this ok? I don't see any interactions with them online.

I've taken Zofran, oral nasal decongestant, nasal spray (not Same ingredients) &.5 Ativan. Is this ok? I don't see any interactions with them online.

Lots of meds: While classic interactions are not described for above meds I still believe you may be able to get rid of few. I assume that you have nausea, nasal congestion and anxiety? Would start by suggesting to stop the nasal decongestant and tapering the Ativan, which is high risk and habit forming.

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Can the drugs Zofran (ondansetron) and emend come in liquid form to be put in an IV to get rid of postop nausea and vomiting?

Can the drugs Zofran (ondansetron) and emend come in liquid form to be put in an IV to get rid of postop nausea and vomiting?

Zofran (ondansetron) comes IV: Zofran (ondansetron) comes in IV form but emend does not. Emend is usually given pre-op (before surgery). Zofran (ondansetron) cane given any time.

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Could the drugs Zofran (ondansetron) and emend come in liquid form to be put in an IV to get rid of postop nausea and vomiting?

Could the drugs Zofran (ondansetron) and emend come in liquid form to be put in an IV to get rid of postop nausea and vomiting?

Zofran (ondansetron) does: Zofran (ondansetron) comes in IV form, and you can ask for it. Emend does not come in IV form as far as I know, but I don't believe emend is the right drug for postop nausea and vomiting.

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Can you take exlax with zofran?

Absolutely.: Zofran is for nausea. Exlax is to treat constipation. They do not interact with each other, so unless you have an allergy or intolerance to one or both medicines, they should be fine to take together. Feel better!

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Zofran (ondansetron) and excessive drowziness?

Yes: If your question is: "can zofran (ondansetron) cause excessive drowsiness? ", the answer is yes. This is especially true for those patients over age 65 or for those taking other medications.

Dr. James Henning
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Ondansetron (Definition)

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Dr. Jeffrey Satinover
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Zofran (Definition)

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