Doctor insights on:
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Yes: yes - should be monitored and a dose reduction may be necessary. ...Read more
Yes if checked by MD: Fatty liver disease has become one of the leading causes of liver disease. Risk factors include obesity, poorly controlled diabetes and elevated triglyceride and blood fat levels. Treatment includes weight loss, diabetes control, avoiding toxins such as alcohol, some medications. Simvastatin is used to control cholesterol and is generally safe. You will need to have some blood work checked. ...Read more
Taking simvastatin and felodipine now have altered liver function, should I continue to take them ?
Can simvastatin affect your liver? i keep retaining fluids and im not eating much so its not the foods. should i ask my doctor to put me on something
Not the cause: While simvastatin causes liver damage extremely rarely (about 1 in 100,000 for serious damage), it's not the likely cause of fluid retention. Issues with your kidneys, previous knee and hip surgeries, malnutrition, hormonal influences, and venous insufficiency are all more likely causes. ...Read more
I have a weak liver. 20mg Atorvastatin daily lowered my liver func. Hence Simvastatin 10mg every alt. day is prescribed. Is it safe for the liver?
...: you will have to continue to monitor this with routine LFTs. elevation in LFts secondary to statin therapy is usually evident in the first 3 months of therapy and is dose dependent. it is recommended to decrease dose or change med if ALT is 3 times the upper limit of normal. if thats the case, pravachol (pravastatin) may ve an option since it is primarily metabolized by the kidneys. ...Read moreSee 1 more doctor answer
Dr prescription liver ultrasx because AST 69, ALT 96 (75/75 3 wks ago), GGT 83. I want to reduce 40mg omeprazole and 20mg simvastatin, alcohol first. Thoughts?
Good ideas-both!: I think your ideas are terrific, and I'd implement them immediately. In so doing you could get your labs rechecked in about one month and see if any positive impact. Having said that, I think its a good idea to still follow your doctor's advice. A liver ultrasound is quite benign (even on the pocketbook, relatively speaking!) and helps exclude important considerations such as gallstone and cancer ...Read more
Rare, but not zero: Most people have no side effects from "statin" medications. A small percentage of people may get muscle symptoms and a very small number can develop life-threatening muscle cell destruction called rhabdomyolysis. Also uncommon are serious liver problems. The benefits of lowering cholesterol far outweigh the risks. Unfortunately, a misguided public scare has exagerated these risks. ...Read more
Usually none: Usually none. Some people report muscle aches or weakness, and some report memory impairment. The majority of these reports turn out not to be from the medication. There are a very small number of potentially life-threatening reactions when muscle cells break down threatening kidney damage. The benefits of cholesterol lowering greatly outweigh the risks for most people. ...Read more