Doctor insights on:
I have been taking Zetia (ezetimibe) 10 mg tablets for about 9 months. I have had body aches and muscle weakness as I have had with other statins. Suggestions?
Try going off med: Zetia (ezetimibe) is not a statin but this med too can cause muscle inflammation. If you have symptoms that might be caused by a med, talk with your doctor and stop it for a while to see how you feel. But do it with your doctor so that you can decide on the plan together. ...Read more
Ezetimibe is the generic name for zetia, (ezetimibe) a medication that decreases absorption of cholesterol from the GI tract. This medication works by blocking the niemann-pick c1-like 1 (npc1l1) protein which allows sterols, including cholesterol, to be absorbed into the intestine. Blocking this protein results in increased production of LDL receptors that then clear LDL ...Read more
Debatable!: Personal opinion only! if i were 96, i would not be taking zetia (ezetimibe). Are we talking about adding years to your life, months to your life or weeks or days to your life. Esoteric to my way of thinking. I would have a very frank discussion with my doctor and decide to stop or continue. I would have to have a very compelling reason to continue this expensive med and want to know why I have to take. ...Read more
Cholesterol blocker: Zetia (ezetimibe) is the brand name for ezitimibe, a medication that works by selectively inhibiting the intestinal absorption of cholesterol and related phytosterols. Zetia (ezetimibe) acts by blocking the niemann-pick c1-like 1 (npc1l1) receptor that is responsible for cholesterol and phytosterol absorption via the intestine. In response, LDL receptors are increased causing reduction in ldl-c and LDL particle number. ...Read moreSee 1 more doctor answer
Yes, But Why?: While you can take both together, polycosonol has not been shown to have a significant effect on blood cholesterol levels. Regarding outcomes, Zetia (ezetimibe) in combination with Simvastatin has shown significant reduction in cardiovascular events in patients with chronic kidney disease. A large trial testing the outcome benefit of Zetia (ezetimibe) added to statin therapy(improve-it trial) is still ongoing. ...Read moreSee 1 more doctor answer