Doctor insights on:
Zerit Nucleoside Reverse Transcriptase Inhibitor
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more
ACE-I: read this: http://circ.ahajournals.org/content/108/3/e16.fullGet a more detailed answer ›
Yes: When it first came out. My patients did and they did not want it anymore. ...Read more
Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis. ...Read more
Father has hepatitis b his alpha feto protein increase from11767 to26434 iu/ml while taking medicines sorafenib200 , entacavir, daflon500, udiliv300 why?
In rheum. arthritis?: Osteoporosis is a known complication of rheumatoid arthritis (ra). The bone loss is related to features of the patient (usually a postmenopausal woman), corticosteroid therapy, and the underlying arthritis disease. May have a beneficial effect on bone loss through the medication's strong anti-inflammatory effect. ...Read more
Not known now. : These drugs were aqpproved for use recently (sitagliptin 2006), and although they have been observed to have side effects in clinical studies, long term effects, including cancer are inconclusive. One "in vitro" study found them to encourage cancer cell metastasis, but long term preclinical studies have not confirmed cancer causing effect. ...Read more
Not really: I am assuming you are asking about hepatits c treatment. Infergen is an old type of interferon. Data suggest that Infergen has little or no benefit after Pegasys (peginterferon alfa 2a) failure. There are new oral medications. These medications (pills) along with Pegasys (peginterferon alfa 2a) and Ribavirin has very good response rate, if you are infected with type i hepatitis c virus. Response rate is doubled from previous treatment. ...Read more
Biochemistry enzymes: One induces and other inhibits action of enzyme. Great Wikipedia question. If you have never heard of it always go there first before coming here. ...Read more
If avodart & flomax are cy3a4 substrates & sprycel (dasatinib) is an inhibitor, why do interaction checkers show a prob. With sprycel (dasatinib) & avodart but not w/flomax?
Good Question: Avodart (dutasteride) is extensively metabolized in humans by the cyp3a4 and cyp3a5 isoenzymes. Flomax (tamsulosin) is extensively metabolized, mainly by cyp3a4 and cyp2d6 isoenzymes. Sprycel (dasatinib) is also extensively metabolized by the cyp3a4 isoenzyme but is also a weak time-dependent inhibitor of cyp3a4 and may therefore potentially increase the concentrations of Avodart and flomax. ...Read more