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Doctor insights on: Zerit Nucleoside Reverse Transcriptase Inhibitor

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How can reverse transcriptase inhibitors work?

Reverse transcriptas: Great wikipedia question. Need much more room than we have here. But basically they inhibit reverse transcriptase by binding to an active site on RT. ...Read more

Dr. Heidi Fowler
11 doctors shared insights

Stavudine (Definition)

Stavudine is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more


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Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets

Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor.    Mk 2206-  akt inhibitor.  Why  prescription for me? It ? Nsclc/mets

Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more

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Is there HIV drug resistance to protease inhibitors?

Is there HIV drug resistance to protease inhibitors?

Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more

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What is nucleoside analogues...does it help hepc cirohtic patients?

What is nucleoside analogues...does it help hepc cirohtic patients?

HCV treatment: most of the current 'about-to-be-ready' regimens are with non-nukes - but you can check out where things are at in the HCV world at this website: www.hcvdrugs.com some wonderful advances are being made - it is an exciting time! ...Read more

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How do ACE inhibitors reverse microalbuminuria?

How do ACE inhibitors reverse microalbuminuria?

Unclear: I don't believe that the mechanism is well understood but they do act on the renal glomerulus, improving membrane integrity, reducing protein leakage, and thus do help microalbumenuria. In addition, they also lower blood pressure which is also beneficial. ...Read more

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Has anyone used lipase inhibitors (orlistat) the fat blocking medication?

Has anyone used lipase inhibitors (orlistat) the fat blocking medication?

Yes: When it first came out. My patients did and they did not want it anymore. ...Read more

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Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

No: Bupropion (wellbutrin) inhibits re-uptake of norepinephrine and Dopamine into neurons (nerve and brain cells). It does not inhibit mao, so there are no dietary restrictions or common medication interactions, unlike the the maois. ...Read more

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Does Dexilant (dexlansoprazole) contain monoamine oxidase inhibitor?

Does Dexilant (dexlansoprazole) contain monoamine oxidase inhibitor?

Dexilant (dexlansoprazole): This is a proton pump inhibitor for treating gerd. It does not contain MAO inhibitor. ...Read more

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Is stanozolol a beta receptor antagonist?

Is stanozolol a beta receptor antagonist?

Stanozolol: Stanozolol is a synthetic anabolic steroid derived from testosterone. It is banned from use in athletes but has a role in some medical conditions. Please look up stanozolol in Wikipedia on the internet. ...Read more

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How to measure anti-dna antibody using farr assay?

How to measure anti-dna antibody using farr assay?

Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis. ...Read more

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Father has hepatitis b his alpha feto protein increase from11767 to26434 iu/ml while taking medicines sorafenib200 , entacavir, daflon500, udiliv300 why?

Father has hepatitis b his alpha feto protein increase from11767 to26434 iu/ml while taking medicines sorafenib200 , entacavir, daflon500, udiliv300 why?

AFP elevation: Given your father's history of chronic hbv infection and elevated afp, he is likely to also have hepatocellular carcinoma. With that high level, this is almost conclusive of malignancy. Suggest to discuss with your physicians in the local area for further care. ...Read more

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Will tnf-alpha inhibitor work against boneloss?

Will tnf-alpha inhibitor work against boneloss?

In rheum. arthritis?: Osteoporosis is a known complication of rheumatoid arthritis (ra). The bone loss is related to features of the patient (usually a postmenopausal woman), corticosteroid therapy, and the underlying arthritis disease. May have a beneficial effect on bone loss through the medication's strong anti-inflammatory effect. ...Read more

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Will copegus (ribavirin) treatment increase liver enzyme levels?

Will copegus (ribavirin) treatment increase liver enzyme levels?

Copegus/liver enzyme: Some people may get worsening of liver functions including elevation of enzymes, bilirubin, brown urine and yellow eyes and medication has to be stopped immediately. ...Read more

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Do dipeptidyl peptidase-4 inhibitors cause cancer, if used in type 2 dm?

Do dipeptidyl peptidase-4 inhibitors cause cancer, if used in type 2 dm?

Not known now. : These drugs were aqpproved for use recently (sitagliptin 2006), and although they have been observed to have side effects in clinical studies, long term effects, including cancer are inconclusive. One "in vitro" study found them to encourage cancer cell metastasis, but long term preclinical studies have not confirmed cancer causing effect. ...Read more

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Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Not really: I am assuming you are asking about hepatits c treatment. Infergen is an old type of interferon. Data suggest that Infergen has little or no benefit after Pegasys (peginterferon alfa 2a) failure. There are new oral medications. These medications (pills) along with Pegasys (peginterferon alfa 2a) and Ribavirin has very good response rate, if you are infected with type i hepatitis c virus. Response rate is doubled from previous treatment. ...Read more

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Enzyme inducers & enzyme inhibitors, what are these?

Enzyme inducers & enzyme inhibitors, what are these?

Biochemistry enzymes: One induces and other inhibits action of enzyme. Great Wikipedia question. If you have never heard of it always go there first before coming here. ...Read more

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If avodart & flomax are cy3a4 substrates & sprycel (dasatinib) is an inhibitor, why do interaction checkers show a prob. With sprycel (dasatinib) & avodart but not w/flomax?

If avodart & flomax are cy3a4 substrates & sprycel (dasatinib) is an inhibitor, why do interaction checkers show a prob. With sprycel (dasatinib) & avodart but not w/flomax?

Good Question: Avodart (dutasteride) is extensively metabolized in humans by the cyp3a4 and cyp3a5 isoenzymes. Flomax (tamsulosin) is extensively metabolized, mainly by cyp3a4 and cyp2d6 isoenzymes. Sprycel (dasatinib) is also extensively metabolized by the cyp3a4 isoenzyme but is also a weak time-dependent inhibitor of cyp3a4 and may therefore potentially increase the concentrations of Avodart and flomax. ...Read more

Dr. Andrew Berry
6 doctors shared insights

Zerit (Definition)

Zerit is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more