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Doctor insights on: Zanaflex Drug Interactions

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Dr. Milton Alvis Jr
133 doctors shared insights

Tizanidine (Definition)

Is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine ...Read more


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Will Zanaflex (tizanidine) cause you to fail a urine drug test?

Will Zanaflex (tizanidine) cause you to fail a urine drug test?

No.: Urine drug testing using modern gas chromatography and mass spectroscopy for confirmatory chemical analysis will not mistake tizanidine (zanaflex) for another substance. ...Read more

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Does Zanaflex (tizanidine) show on a drug screening?

Does Zanaflex (tizanidine) show on a drug screening?

depends: While Zanaflex (tizanidine) isnot one of the routine five panel tests, I have seen multiple non-federal panels that contain it and a lot more. If you have a legitimate prescription which can be verifid through a pharmacy you needn't worry. ...Read more

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My pain dr says I can't take my celexa with my baclofen( he approved 4 9 months) is there another drug 2 take in place of baclofen?Besides zanaflex (tizanidine)?

My pain dr says I can't take my celexa with my baclofen( he approved 4 9 months) is there another drug 2 take in place of baclofen?Besides zanaflex (tizanidine)?

Need to ask Pain Doc: Yes, you have other options but you need to ask your pain doc. First, epocrates claims no significant interaction btwn Celexa (citalopram) & baclofen. Drugs.Com says there is a possible interaction http://bit.Ly/heiote. Second, alternatives to Baclofen & tizanidine include cyclobenzaprine, carisoprodol, dantrolene, metaxalone, Methocarbamol & orphenadrine as muscle relaxants per epocrates. ...Read more

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I take Zanaflex (tizanidine) or flexeril (have both) and just started necon 10/11. I read there could be interactions with zanaflex (tizanidine). Do i need to be concerned?

I take Zanaflex (tizanidine)  or flexeril (have both) and just started necon 10/11. I read there could be interactions with zanaflex (tizanidine). Do i need to be concerned?

Yes, it is possible: Zanaflex (tizanidine) & Flexeril are muscle relaxants, while Necon 10/11 is an oral contraceptive.All the three medications are metabolized in the liver through cyp450. Necon is an inhibitor of 3a4 sub-enzyme, while Zanaflex (tizanidine) and Flexeril are not. Necon may increase the levels of Flexeril and zanaflex, (tizanidine) causing increased sedation, dizziness, impairment of fine motor movements, coordination and risk of fall. ...Read more

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Any drugs 4 spasticity that could replace baclofen, and be taken with celexa safely? Except I am allergic 2 zanaflex (tizanidine)..Plz help I need my celexa back!

Any drugs 4 spasticity that could replace baclofen, and be taken with celexa safely? Except I am allergic 2 zanaflex (tizanidine)..Plz help I need my celexa back!

Possibly: Clonazepam is a possibility but is a controlled substance and is not prescribed unless you really have problems with he baclofen. It causes dependence and is pretty hard to wean from. ...Read more

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Dr. Dariush Saghafi
1 doctor shared a insight

Drug Interaction (Definition)

When the combination of two agents cause an effect, intended or unintended, that would not have otherwise ...Read more


Dr. Tipu Sultan
124 doctors shared insights

Zanaflex (Definition)

Zanaflex is a muscle relaxant which is a ...Read more