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Doctor insights on: Z Pack Sinus Infection

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Started 3day z-pack for sinus infection on 3/4/14. Congestion got better for about two days but is now back. Go back to Dr. or wait it out?

Started 3day z-pack for sinus infection on 3/4/14.  Congestion got better for about two days but is now back. Go back to Dr. or wait it out?

Z pack not answer: AZYTHROMYCIN is not the "greatest" antibiotic for sinus infection since the blood levels are often not high enough to reach deep sinus infections. Furthermore, there are RESISTANT organisms being described (probably due to OVERUSE of the Z Pac) You need a longer course of therapy with an antibiotic which reaches the sinuses. Ask your PCP to refer you to an ENT specialist .... ...Read more

Dr. Patricia Foster
3 doctors shared insights

Sinus (Definition)

In anatomy, a sinus is a cavity within a bone or other tissue. Most commonly found in the bones of the face and connecting with the nasal cavities. Sinus (anatomy), description of the general term paranasal sinuses, air cavities in the cranial bones, especially those near the nose, including: the maxillary sinuses, also called the maxillary antra and the largest of the ...Read more


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I am taking azithromycin (as z-pack) for a sinus infection; finished course this morning and I am improved but still congested. Will it keep working?

I am taking azithromycin (as z-pack) for a sinus infection; finished course this morning and I am improved but still congested. Will it keep working?

Long half life : Zithromax is a unique medicine that is taken for a shorter duration but continues to work for many days after taking the last pill. If one's symptoms continue to improve, no problem. If one's symptoms worsen after the last pill, time to see your doctor again. ...Read more

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I have 1 eye that off and on has swollen, the skin is red. I don't have allergies. My doctor gave me a z pack for a sinus infection but no change.

 I have 1 eye that off and on has swollen, the skin is red.  I don't have allergies.  My doctor gave me a z pack for a sinus infection but no change.

You should go: back to your doctor to see if another treatment would be necessary. If symptoms do not improve, ask for a referral to an ENT specialist. ...Read more

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Treated with Z pack for pneumonia and sinus infection. My neck, shoulders and head hurt so bad that I can't hardly stand it.

Treated  with Z pack for pneumonia and sinus infection.  My neck, shoulders and head hurt so bad that I can't hardly stand it.

Need more info: While a z-pack might be adequate for a simple pneumonia there is increasing resistance to its effects and we generally prescribe the full 500 every day instead of the 250mg/day in the pack. It is also not adequate treatment for a true sinusitis which should be treated for at least 14 days with Augmentin (amoxicillin and clavulanate) or cefuroxime. Knowing if u just started or have finished the z-pac would help us advise you ...Read more

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I took Aleve (naproxen) for muscle pain this afternoon and am already taking a z pack for a sinus infection later today i drank a 5 hour energy to help me study ?

I took Aleve (naproxen) for muscle pain this afternoon and am already taking a z pack for a sinus infection later today i drank a 5 hour energy to help me study ?

What is the question: Zpack is an antibiotic (zithromax) which is safe to take with aleve (naproxen) which is an anti-inflammatory pain reliever which can alleviate the symptoms of sinus congestion pain (a decongestant may help as well if your blood pressure is fine - eg. Pseudoephedrine). I am not a fan of the 5 hour energy drink- but probably not harmful in this situation if only 1. You may need rest for recovery. ...Read more

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I have a sinus infection does z pack work?

Not recommended: Antibiotics are not recommended for sinus infections unless they are unusually long-lasting or severe. Use decongestants. ...Read more

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Can being exposed to sewer being broken have anything to sinus infection lastimg weeks even if I took 2 rounds of z pack? Have had infection 3 mths.

Can being exposed to sewer being  broken have anything to sinus infection lastimg weeks even if I took 2 rounds of z pack?  Have had infection 3 mths.

No: If Azithromycin has twice failed, it is likely the wrong antibiotic since it is convenient but not first line treatment for acute sinusitis. Penicillins, cephalosporins and fluoroquinolines are much more effective for sinusitis. Speak with or see your provider and make sure you have an infection rather than allergies or another cause for symptoms. If infected, suggest a change in antibiotics. ...Read more

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Azithromycin (Definition)

Azithromycin (zithromax, azithrocin, zmax, azin)[1] is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics.[2][not in citation given (see discussion.)] it is derived from erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus making ...Read more


Dr. Gregory Moneta
9 doctors shared insights

Infection (Definition)

Infections are invasions of some other organism (fungus, bacteria, parasite) or viruses into places where they do not belong. For instance, we have normal gut bacteria that live within us without causing problems; however, when those penetrate the bowel wall and enter the bloodstream, ...Read more