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Doctor insights on: Xiaflex

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Can xiaflex (collagenase clostridium histolyticum) be used on depuytrens in the feet?

Can xiaflex (collagenase clostridium histolyticum) be used on depuytrens in the feet?

Xiaflex (collagenase clostridium histolyticum) in the feet: To treat ledderhose disease as it is called is currently an "off label" treatment. In the us this means it is not an official recognized treatment associated with the drug xiaflex (collagenase clostridium histolyticum). A literature search will not reveal any significant clinical study published study in peer reviewed literature. One must be careful not to take a patient's stated positive experience if they have had this as the results may be very dependent upon many factors including clinical stage, health and of course subjective interpretation of what a good result is. This does not mean that there are dedicated people who wan tot help others just "caveat emptor". ...Read more

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How long does the effect of a fluphenazine injection last?

How long does the effect of a fluphenazine injection last?

Depends . . .: Fluphenazine is an antipsychotic that can be given as a normal injection w/half-life of 15hrs or a long-acting injection w/half-life of 6-10 days depending upon the chemical formulation. We typically guesstimate that a chemical takes 5 half-lives to get out of your system, so the effect of an injection could be anywhere from a few days to two months. ...Read more

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Treating Clostridium Difficile Infection (Checklist)

Know it's a common complication of taking antibiotics
Once
Minimize use of broad spectrum antibiotics & stay out of hospitals
Once
Use probiotics to outcompete the clostridium difficile bacteria
Once
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How long is 25 hour half life?

How long is 25 hour half life?

Depends.: I am assuming you are talking about the half life of a drug. A drug with a 25 hours half life means that after 25 hours, the blood concentration of the drug will be halved. So at hour zero it's 100%. At 25 hours , the concentration is 50%. At 50 hours, it's 25%. At 75 hours, it's 12.5% etc. Please note that using half lives is an oversimplification and doesn't always correlate with drug effect. ...Read more

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What is the halflife of flagyl?

What is the halflife of flagyl?

Halflife = 6-8 hours: The average elimination half-life of Metronidazole is reported as 6-7 hours in some studies, but is more commonly reported as 7-8 hours. The half-life can be affected by age, kidney insufficiency, and/or liver damage. The half-life of Metronidazole is much longer in children, and has been reported as 22-109 hours in newborns. ...Read more

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Is there some kind of all day mouthguard that i can wear around all day?

Is there some kind of all day mouthguard that i can wear around all day?

DEFINITELY: A less thick, soft, clear lower mouthpiece can be worn during the day. But it needs to be custom made by a dentist. Best to have it on the lower teeth! ...Read more

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What happens if i think the worse scenario very often and i feel this is deteriorating my life. How do I stop it and interact more with life?

What happens if i think the worse scenario very often and i feel this is deteriorating my life.  How do I stop it and interact more with life?

Anxiety Disorder: Anticipation of worst happening (even if it is exceedingly unlikely) is a symptom of anxiety disorder. This is a distortion of the normal fight or flight response every human is endowed with. Your brain seems to be wired for flight for any environmental stimulus, no matter how trivial. If this is so, see doctor for exam & to formulate a therapeutic plan to include counseling & medication as needed. ...Read more

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Do you think that a child could be born mentally ill, or it comes from his interactions with his world?

Do you think that a child could be born mentally ill, or it comes from his interactions with his world?

Both: Genetic predisposition can be a factor and environment can be a factor. Depends on the mental illness. Some respond well to nutrients. Check out www.Truehope.Com for some really great information. ...Read more

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How to identify suitable skincare product for a combination skin?

How to identify suitable skincare product for a combination skin?

Find the right doc: I feel strongly about this topic, because unfortunately there are too many pros that fall victim to the same hype that the general public does. Find someone who truly believes in good scientifically- based skin care that can truly make a difference, not the newest fad. If they can't explain it to you in terms that make sense, move on. There is no substitute for good medicine, especially in skin. ...Read more

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Is there any truth behind "fit for life's" theory of proper food combinations?

Is there any truth behind "fit for life's" theory of proper food combinations?

Maybe: Maybe more than we usually give credit for. U must observe how ur body responds to food that u eat. Try it and see how your feel. They advocate generally healthy foods. ...Read more

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Is there such thing as exercising too much?

Is there such thing as exercising too much?

Yes!: Over exercise & do not allowing your body time to repair itself, can lead to muscle breakdown (rhabdomyolysis), rather than buildig muscle. Also, if you are not eating properly for the amount of exercise you are doing, you can damage your body by burning too many calories that body needs to do everyday functions. It also puts you at risk for muscle & joint injuries. Make sure to rest & eat enough. ...Read more

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How many inches does a women lose in height as she ages?

How many inches does a women lose in height as she ages?

1-3 inches: From their peak height, women tend to lose about 1-3 inches over a few decades. Somethings such as osteoporosis may cause a much greater loss of height. ...Read more

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Can xiaflex (collagenase clostridium histolyticum) be used on depuytrens in the feet?

Xiaflex (collagenase clostridium histolyticum) in the feet: To treat ledderhose disease as it is called is currently an "off label" treatment. In the us this means it is not an official recognized treatment associated with the drug xiaflex (collagenase clostridium histolyticum). A literature search will not reveal any significant clinical study published study in peer reviewed literature. One must be careful not to take a patient's stated positive experience if they have had this as the results may be very dependent upon many factors including clinical stage, health and of course subjective interpretation of what a good result is. This does not mean that there are dedicated people who wan tot help others just "caveat emptor". ...Read more

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Could my penis curvature to the left be corrected by injecting Xiaflex into the fibrous tissue ?

Could my penis curvature to the left be corrected by injecting Xiaflex into the fibrous tissue ?

Not necessary but...: Is your penile curvature new or lifelong? To what degree? How has it mentally and physically bothered you? All these & more have to be clarified before treating it. How to handle your concern? Go to articles listed in http://www.formefirst.com/onDealSickness.html. Xiaflex is only for occasional cases of Peyronie's disease. More? Ask urologists timely. ...Read more

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Why does xanaflex make me thirsty?

Why does xanaflex make me thirsty?

Side effect: Dry mouth is one of the most common side effects of this medication (a centrally acting ?2-adrenergic agonist), seen in about 50% of patients who use it. ...Read more

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Take xanflex 4mg. If i take one during the day, i get tired and if i nap i wake up thirsty. Is this the med or me?

Take xanflex 4mg. If i take one during the day, i get tired and if i nap i wake up thirsty. Is this the med or me?

It's a common: Side effect of this medication. Try to take it before you sleep and not during the daytime. Also if you are mixing it with narcotics it could be exacerbating you symptoms. Goof luck. ...Read more

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Dr.Rx's for anxiety dep.Clon 1mg 4x, cymbalta120 day, remeron40mg bed, xanaflex 12mg day.Still anxious..Been on meds 24 years therapy never worked.Also ?

Dr.Rx's for anxiety dep.Clon 1mg 4x, cymbalta120 day, remeron40mg bed, 
xanaflex 12mg day.Still anxious..Been on meds 24 years therapy never worked.Also ?

Other options: May be worth to consider, like transcranial magnetic stimulation (tms), electro convultive therapy (ect), biofeedback, etc. The best would 2 discuss them w/ur doctor. You r taking 2 antidepressants & 2 anxiolytics. Some drs would add an atypical anti psychotic but polypharmacy is 2 b avoided. Please take action, know there are other options & discuss them w/ur doc. U want results & u r right! best. ...Read more

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