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Doctor insights on: Xanax Half Life

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How long is Extended Release 2mg Xanax (alprazolam) half life, compared to 2mg Klonopin half life?

How long is Extended Release  2mg Xanax (alprazolam) half life, compared to 2mg Klonopin half life?

Xanax (alprazolam) XR vs Klonopin: The half-life for Xanax (alprazolam) XR is short 10.7–15.8 hours and the longer-term efficacy of Xanax (alprazolam) XR has not been systematically evaluated. Klonopin has an unusually long elimination half-life of 18–50 hours, it considered the longest-acting benzodiazepine. ...Read more

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Dr. Alan Ali
905 doctors shared insights

Alprazolam (Definition)

Alprazolam is a short acting benzodiazepine, it does not last long in the system . So when used regularly with multiple doses to treat anxiety, it is associated with inter-dose withdrawal, tolerance and a resulting increase level of baseline anxiety. So in anxiety clinics, we use it only in cases of " flight , dentist or other infrequent anxieties, ...Read more


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Asked a question before about tapering xanax (alprazolam). Was told to switch to a benzo with a longer half life any recommendations.

Asked a question before about tapering xanax (alprazolam). Was told to switch to a benzo with a longer half life any recommendations.

Right idea: Getting off benzodiazepines is a difficult proposition. You undergo withdrawal symptoms like anxiety, panic, sleep disturbance, irritability and anger. However the most dangerous withdrawal symptom is withdrawal seizure. It can be lethal. It is recommended that you be switched to a longer acting benzodiazepine like Clonazepam or diazepam to help ease the withdrawal. ...Read more

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Hello, what are the advices to survive the benzo withdrawal? Took xanax (alprazolam) 1mg for 8 months, tapered and 8 days no benzo. Having worse time in my life.

Hello, what are the advices to survive the benzo withdrawal? Took xanax (alprazolam) 1mg for 8 months, tapered and 8 days no benzo. Having worse time in my life.

Hard addiction: Benzo addiction is worse . If someone needs to rehab on alcohol 10 days is enough. If opiates you need 20 days but for Benzo you need 30 days. Especially Xanax (alprazolam) is the worst of the Benzos. Xanax (alprazolam) is very fast and shirt acting powerful monster that you will be craving for it .need to be patient and withdraw gradually over one full month ...Read more

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I feel normal since I've been takind my meds, aderal, xanax, (alprazolam) Suboxone due to med conditions.Without them, my life isnt right.If it wrks shld i keep tkg thm?

I feel normal since I've been takind my meds, aderal, xanax, (alprazolam) Suboxone due to med conditions.Without them, my life isnt right.If it wrks shld i keep tkg thm?

Medication management: Good question , if you're working closely with someone that you can talk to that is primary. You should not be and swayed by other then trusted physician unless those closest to you are truly concerned about how you're behaving. Suboxone and Adderall are excellent drugs for what has become physical problems in your brain. Adderall my be forever Suboxone you can eventually end. Xanax (alprazolam) not the best. ...Read more

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I feel normal since I've been takind my meds, aderal, xanax, (alprazolam) Suboxone due to med conditions.Without them, my life isnt right.If it wrks shld i keep tkg thm?

I feel normal since I've been takind my meds, aderal, xanax, (alprazolam) Suboxone due to med conditions.Without them, my life isnt right.If it wrks shld i keep tkg thm?

Probably. yes!: It sounds like you are very pleased with the effects that your doctor(s) have helped you achieve. Let them know that! everyone likes to feel successful when they are. Work with them to plan for the future. They may think that it makes sense to see if a reduction is possible at times. They've done well, trust them. ...Read more

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Which is better for someone with severe anxiety that effects thir entire life. Xanax (alprazolam) or ativan? Which would help most.

Which is better for someone with severe anxiety that effects thir entire life. Xanax (alprazolam) or ativan? Which would help most.

For severe anxiety: I would not be relying only on pharmaceuticals, but would also want to work on the specific anxieties the patient has. Cognitive therapy, mindfulness meditation, dynamic psychotherapies, all help the person learn about his/her own triggers and ways of dealing with them. Ssri antidepressants seem better at preventing panic attacks than episodic benzodiazepines (whether using xanax (alprazolam) or ativan). ...Read more

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Been on same Xanax (alprazolam) dose for 4yrs due to severe anxiety/panic (1mg as needed, 30/month rx)- saved my life. Why r drs so averse 2 prescribing it now?

Been on same Xanax (alprazolam) dose for 4yrs due to severe anxiety/panic (1mg as needed, 30/month rx)- saved my life. Why r drs so averse 2 prescribing it now?

Prevention: Most doctors would want to help prevent panic attacks -- rather than wait for them to happen, and then treat sporadically with xanax (alprazolam). Xanax (alprazolam) is meant to be temporary, can be habit-forming, and is not preventative for panic. Other medications, such as ssri's, etc, are preventive; it's also important to work on the anxiety in psychotherapy. ...Read more

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What is the half-life of Xanax (alprazolam) in terms of saftely drinking beer?

Xanax (alprazolam) and alcohol: It is no so much the half life that is problematic in mixing alcohol with sedatives it is the fact that these drugs are easily and rapidly stored in fat cells. Alcohol binges have unpredictable effects on fat cells and additive effect with xanax (alprazolam). So the term safely drinking beer with xanax (alprazolam) have high probability of causing destructive physiological and neurological consequences. ...Read more

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What is the half-life of Xanax (alprazolam) in terms of saftely drinking beer? I've heard anywhere from 8 to 24 hours.

More like 24 hours.: In a healthy individual, the anti-anxiety effect of xanax (alprazolam) is felt in 20 min., peaks in about an hour & lasts for 5 hrs. Xanax (alprazolam) half-life is 11-12 hours and several times the half-life is needed to eliminate the drug. Using xanax (alprazolam) with alc. As a rule is dangerous or even deadly for several reasons. Effects of alc. On the liver function is one and the synergistic effects on the brain is the other. ...Read more

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Why does a long half-life mean a long withdrawal? Xanax (alprazolam) and oxycodone have short hls but w/d can last months. Why would suboxone. Be longer?

Why does a long half-life mean a long withdrawal? Xanax (alprazolam) and oxycodone have short hls but w/d can last months. Why would suboxone. Be longer?

Time Dependency: Narcotic withdrawal times and severity are complex phenomena and not easy to summarize. The time it takes the body to get rid of narcotics (half-lives) may have far more to do with length and severity of dependence, malnutrition, sleep deprivation and kidney and liver function than the pharmacokinetic profile of the drug. Please speak with your pain management specialist for specific advice. ...Read more

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Xanax (Definition)

Alprazolam is a short-acting benzodiazepine which is a kind of sleep-inducing drug ...Read more