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Doctor insights on: Xanax And Amitriptyline

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Dr. Alan Ali
905 doctors shared insights

Alprazolam (Definition)

Alprazolam is a short acting benzodiazepine, it does not last long in the system . So when used regularly with multiple doses to treat anxiety, it is associated with inter-dose withdrawal, tolerance and a resulting increase level of baseline anxiety. So in anxiety clinics, we use it only in cases of " flight , dentist or other infrequent anxieties, ...Read more


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Take Xanax (alprazolam) .5 mg & amitriptyline 12.5mg HS for sleep. Is it ok to take st johns wort in the morning to help with positive mood?

Take Xanax (alprazolam) .5  mg & amitriptyline 12.5mg HS for sleep. Is it ok to take st johns wort in the morning to help with positive mood?

No.: St. John's Wort hastens the breakdown of Amitriptyline and taking both will be counterproductive. If you still need something to make you feel positive, go back to your doctor and have him reevaluate your medications. ...Read more

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I am prescribed .50mg Xanax (alprazolam) 3/daily, 75mg Amitriptyline, and 50mg Trazadone. I'm 6'1, 232 male. Is this safe?

 I am prescribed .50mg Xanax (alprazolam) 3/daily, 75mg Amitriptyline, and 50mg Trazadone. I'm 6'1, 232 male. Is this safe?

OVERLAPPING MEDS: The combo of Meds you are on looks like you are being treated for anxiety and depression . Xanax (alprazolam) is short acting for anxiety . Trazadone and amitriptyline are long acting for anxiety and depression but are very similar and both cause weight gain.. I would taper trazadone and start cymbalta. You need full lab work up including TFTS. Also a sleep study to rule out sleep apnea. ...Read more

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Are amitriptyline and Xanax (alprazolam) similar?

Are amitriptyline and Xanax (alprazolam) similar?

NO: Amitriptyline is a tricyclic antidepressant for depression and some forms of anxiety, sometimes used for chronic pain or migraine. Xanax (alprazolam) is a triazolobenzodiazepine or a benzodiazepine with an extra triazole ring structure. It is quite addicting and has a short half-life. It is used for panic, with or without agoraphobia, generalized anxiety disorder and for anxiety associated with chemotherapy. ...Read more

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Can I take amitriptyline and xanax (alprazolam) simultaneously? I'm prescribed both but usually wait a few hours between different doses.

Talk to your doctor : Both medications can be sedating. When combined there is an increased sedating effect. It depends upon your age and the dose of your medication and your overall health in order to determine if it is safe to combine the two. Talk to your doctor for the safest answer to your question. ...Read more

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Is it safe to take amitriptyline with Xanax (alprazolam) at night?

Yes, in low doses: They will have additive sedation and you need individual guidance from a physician, but they are not inherently dangerous together. ...Read more

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Please doctor, can you tell me if amitriptyline is like xanax (alprazolam)?

Please doctor, can you tell me if amitriptyline is like xanax (alprazolam)?

NOT ALIKE: Amitriptyline is a tricyclic antidepressant for depression and some forms of anxiety, sometimes used for chronic pain or migraine. Xanax (alprazolam) is a triazolobenzodiazepine or a benzodiazepine with an extra triazole ring structure. It is quite addicting and has a short half-life. It is used for panic, with or without agoraphobia, generalized anxiety disorder and for anxiety associated with chemotherapy. ...Read more

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Dr gave amitriptyline 50mg for pain & insomnia. Seems to help some w/pain, not so much for insomnia. Is higher dose safe w/citalopram& 0.5 xanax (alprazolam)? Ty

Dr gave amitriptyline 50mg for pain & insomnia. Seems to help some w/pain, not so much for insomnia. Is higher dose safe w/citalopram& 0.5 xanax (alprazolam)? Ty

See a psychiatrist: For the best understanding of your medication needs (vs. A family practice doctor). Psychiatrists have much more training in the type of medications are you taking. Take care. ...Read more

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Hi Doctor, I'm taking amitriptyline 10mg every day (bed time - 10mg). I would like to know if I can take Xanax (alprazolam) 25mg this morning as I feel anxious. Thanks for your help?

1 + 1 May Equal 10: Look, getting in the habit of taking this & that for that & this is not generally a good idea. Sure, take a Xanax (alprazolam) if you need to, but if you find yourself taking them more than a couple times a month you need help.Plus I don't know what the amitriptyline is for(pain? depressiion?) & you should know what might be making you anxious and deal with it (again,get help). Side effects add up.Do the math. ...Read more

Dr. Robert Kent
363 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
306 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more