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Doctor insights on: Xanax And Amitriptyline

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Dr. Alan Ali
934 doctors shared insights

Alprazolam (Definition)

Alprazolam is a short acting benzodiazepine, it does not last long in the system . So when used regularly with multiple doses to treat anxiety, it is associated with inter-dose withdrawal, tolerance and a resulting increase level of baseline anxiety. So in anxiety clinics, we use it only in cases of " flight , dentist or other infrequent anxieties, ...Read more


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Take Xanax (alprazolam) .5 mg & amitriptyline 12.5mg HS for sleep. Is it ok to take st johns wort in the morning to help with positive mood?

Take Xanax (alprazolam) .5  mg & amitriptyline 12.5mg HS for sleep. Is it ok to take st johns wort in the morning to help with positive mood?

No.: St. John's Wort hastens the breakdown of Amitriptyline and taking both will be counterproductive. If you still need something to make you feel positive, go back to your doctor and have him reevaluate your medications. ...Read more

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I am prescribed .50mg Xanax (alprazolam) 3/daily, 75mg Amitriptyline, and 50mg Trazadone. I'm 6'1, 232 male. Is this safe?

 I am prescribed .50mg Xanax (alprazolam) 3/daily, 75mg Amitriptyline, and 50mg Trazadone. I'm 6'1, 232 male. Is this safe?

OVERLAPPING MEDS: The combo of Meds you are on looks like you are being treated for anxiety and depression . Xanax (alprazolam) is short acting for anxiety . Trazadone and amitriptyline are long acting for anxiety and depression but are very similar and both cause weight gain.. I would taper trazadone and start cymbalta. You need full lab work up including TFTS. Also a sleep study to rule out sleep apnea. ...Read more

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Are amitriptyline and Xanax (alprazolam) similar?

Are amitriptyline and Xanax (alprazolam) similar?

NO: Amitriptyline is a tricyclic antidepressant for depression and some forms of anxiety, sometimes used for chronic pain or migraine. Xanax (alprazolam) is a triazolobenzodiazepine or a benzodiazepine with an extra triazole ring structure. It is quite addicting and has a short half-life. It is used for panic, with or without agoraphobia, generalized anxiety disorder and for anxiety associated with chemotherapy. ...Read more

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Can I take amitriptyline and xanax (alprazolam) simultaneously? I'm prescribed both but usually wait a few hours between different doses.

Talk to your doctor : Both medications can be sedating. When combined there is an increased sedating effect. It depends upon your age and the dose of your medication and your overall health in order to determine if it is safe to combine the two. Talk to your doctor for the safest answer to your question. ...Read more

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Is it safe to take amitriptyline with Xanax (alprazolam) at night?

Yes, in low doses: They will have additive sedation and you need individual guidance from a physician, but they are not inherently dangerous together. ...Read more

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Please doctor, can you tell me if amitriptyline is like xanax (alprazolam)?

Please doctor, can you tell me if amitriptyline is like xanax (alprazolam)?

NOT ALIKE: Amitriptyline is a tricyclic antidepressant for depression and some forms of anxiety, sometimes used for chronic pain or migraine. Xanax (alprazolam) is a triazolobenzodiazepine or a benzodiazepine with an extra triazole ring structure. It is quite addicting and has a short half-life. It is used for panic, with or without agoraphobia, generalized anxiety disorder and for anxiety associated with chemotherapy. ...Read more

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Hi Doctor, I'm taking amitriptyline 10mg every day (bed time - 10mg). I would like to know if I can take Xanax (alprazolam) 25mg this morning as I feel anxious. Thanks for your help?

1 + 1 May Equal 10: Look, getting in the habit of taking this & that for that & this is not generally a good idea. Sure, take a Xanax (alprazolam) if you need to, but if you find yourself taking them more than a couple times a month you need help.Plus I don't know what the amitriptyline is for(pain? depressiion?) & you should know what might be making you anxious and deal with it (again,get help). Side effects add up.Do the math. ...Read more

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Dr gave amitriptyline 50mg for pain & insomnia. Seems to help some w/pain, not so much for insomnia. Is higher dose safe w/citalopram& 0.5 xanax (alprazolam)? Ty

Dr gave amitriptyline 50mg for pain & insomnia. Seems to help some w/pain, not so much for insomnia. Is higher dose safe w/citalopram& 0.5 xanax (alprazolam)? Ty

See a psychiatrist: For the best understanding of your medication needs (vs. A family practice doctor). Psychiatrists have much more training in the type of medications are you taking. Take care. ...Read more

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Can I take Xanax (alprazolam) with my neurontin and amitriptyline (both for migraines)? Was prescribed Xanax (alprazolam) for panic attacks.

Well: Xanax (alprazolam) is a very dangerous drug. It is highly addicting. Now I would avoid that drug and if you suffer from panic attacks there are safer choices of medication that have been approved for panic attacks Xanax (alprazolam) is not one of those ...Read more

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I take hydrocodone, cyclobenzaprine, amitriptyline, xanax, (alprazolam) and cymbalta. Xanax (alprazolam) as needed, cymbalta brand new - causing nausea. Can I take ondansetron?

I take hydrocodone, cyclobenzaprine, amitriptyline, xanax, (alprazolam) and cymbalta. Xanax (alprazolam) as needed, cymbalta brand new - causing nausea. Can I take ondansetron?

Wouldn't recommend: you are already on several drugs which inhibit serotonin reuptake, increasing their levels - amitriptylene, Cymbalta (duloxetine) and cyclobenzaprine all have that potential, and ondansetron does it big time. This can result in the serotonin syndrome which is dangerous and even potentially fatal. All of these drugs also produce sedation. I would talk with your provider and pharmacist about safety of this. ...Read more

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I am taking elavil, nuvigil, remeron, and Xanax (alprazolam) for anxiety/depression/chronic daily fatigue. The first 3 have me in a fog. Will weaning off help me?

I am taking elavil, nuvigil, remeron, and Xanax (alprazolam) for anxiety/depression/chronic daily fatigue. The first 3 have me in a fog.  Will weaning off help me?

Yes: Weaning off medication may help. Nuvigil is not usually sedating or causing "fog", the three other medications could. Discuss adjusting medication with treating physician, it is not safe to abruptly stop all of these medications. ...Read more

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I have been having a rlly hard time sleeping last 10 days. About 2 hours a night. I have tried Lunesta, (eszopiclone) Xanax, and last night amitryptaline What todo?

I have been having a rlly hard time sleeping last 10 days. About 2 hours a night. I have tried Lunesta, (eszopiclone) Xanax, and last night amitryptaline What todo?

Other meds: make sure you're not taking in caffeine from coffee or energy drinks. try to get up the same time each day regardless of how poorly you slept. limit daytime naps to no more than 20 mins consider zyprexia trazodone or remeron (mirtazapine) as these generally are very sedating ...Read more

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Are there risks related to sun exposure when using any of the following: hydrocodone, cyclobenzaprine, amitriptyline, cymbalta, or xanax (alprazolam)?

Here it is: 1. Amitriptyline could increase the risk of overheating and photosensitivity. 2. cyclobenzaprine could increase the risk of photosensitivity only. 3. Cymbalta has no risks. 4. hydrocodone has no risks. 5. Xanax (alprazolam) could increase the risk of photosensitivity only. Do not stop taking any prescribed medication without first talking to your doctor. ...Read more

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I'm on elavil (amitriptyline) 25 yrs.150 mg. For depression & anxiety-xanax on & off could i switch to ssri. I'd need ssri w/ sedative effect like elavil (amitriptyline) - recommend?

I'm on elavil (amitriptyline) 25 yrs.150 mg. For depression & anxiety-xanax on & off could i switch to ssri. I'd need ssri w/ sedative effect like elavil (amitriptyline) - recommend?

Options are availabl: Alternatives to xanax (alprazolam) are available. Discuss options with your physician. Abrupt unsupervised discontinuation of high regular xanax (alprazolam) doses can lead to withdrawal symptoms and possibly seizures. ...Read more

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Dr. Robert Kent
375 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
322 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more