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Doctor insights on: Worst Wegeners Granulomatosis Symptom

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Causes of wegeners granulomatosis and treatment?

Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

Dr. Milroy Samuel
30 doctors shared insights

Granulomatosis (Definition)

A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive ...Read more


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Has anyone ever heard of the disease wegeners granulamatosis?

Has anyone ever heard of the disease wegeners granulamatosis?

Yes: Wegener's granulomatosis with polyangiitis is an incurable form of vasculitis (inflammation of blood vessels) that affects the lungs, kidneys, and other organs. Due to its organ damage, it is life-threatening and requires long-term immunosuppression. Five-year survival is up to 87%, with some of the mortality due to toxicity of treatment. Since that is an average figure, some will live longer. ...Read more

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What is the disease wegeners granulamatosis in kids?

What is the disease wegeners granulamatosis in kids?

WG: Wegener’s granulomatosis (WG) is a rare disease that causes the walls of blood vessels to become inflamed (called vasculitis). This limits blood flow to tissues and can affect any organ. WG is a type of autoimmune disease. This means the body’s immune system attacks its own tissues. Its cause is unknown. ...Read more

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What are symptoms of wegener's granulomatosis?

See details: The most common presenting symptom is a chronic sinusitis but there can be numerous other issues associated with wegener's including arthritis, pneumonia, eye problems, kidney disease and cardiac and neurologic issues. ...Read more

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What are the common symptoms associated with wegener's granulomatosis?

What are the common symptoms associated with wegener's granulomatosis?

Rash sinus lung: It is called polyangiitis with granulomatosis and is different in different people. This problem is caused by inflammation in the blood vessels which go everywhere in the body. Common symptoms include rash, sinus inflammation, lung problems which can be manifest by a cough. The kidney can be involved also but often this is asymptomatic. We can see other sites like the eyes, nose, etc. ...Read more

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How long can wegeners go undiagnosed? Can a patirnt have vague symptoms (still be able to funcion) for months before a diagnosis is made?

How long can wegeners go undiagnosed?  Can a patirnt have vague symptoms (still be able to funcion) for months before a diagnosis is made?

Yes!: Delayed diagnosis can be caused by "vague" symptoms; mild disease at onset; the fact that wegener's is quite uncommon for an autoimmune disease. This rheumatic immune problem is best dealt with by a specialist in rheumatology. ...Read more

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Can breast lump be caused by wegener's granulomatosis? What are the other symptoms?

Can breast lump be caused by wegener's granulomatosis? What are the other symptoms?

No, not likely: Wegner's causes nasal and sinus problems and respiratory symptoms like cough and lung nodules. It affects kidneys which shows up as rising creatinine and abnormal urinalysis. ...Read more

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How can I live with wegeners disease?

How can I live with wegeners disease?

Vasculitis : Wegeners granulomatosis now known as granulomatosis with polyangiitis is incurable vasculitis that effects the nose , lungs , and kidneys. It requires life long immunosupressant. With treatment five year survival is 87%. ...Read more

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Could a bronchoscopy tell what caused wegener's granulomatosis?

Could a bronchoscopy tell what caused wegener's granulomatosis?

No it cannot: A bronchoscopy is useful for identifying that wegener's is affecting the lungs but it will not tell you the cause. Wegener's is in a class of conditions known as autoimmune. This is where the body does not recognize its own cells as being "self". In turn an immune response causes inflammation in the lungs, eyes and sinuses (the classic locatioins in the body to be affected by wegeners). ...Read more

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Please tell me what orofacial granulomatosis is?

Please tell me what orofacial granulomatosis is?

See details: This is an inflammatory condition effecting the face and lips. It is most common in the early adult years. Occasionally there may also be swelling or burning of the tongue or gums. It seems to occur more commonly in patients with Crohn's disease and sarcoidosis. However, the cause is unknown.TNF agents such as Remicade (infliximab) are now considered the treatment of choice. ...Read more

Dr. Stephen Scholand
32 doctors shared insights

Wegener's Granulomatosis (Definition)

Wegener's Granulomatosis is a medical condition in which the blood vessels supplying the nose, lungs, kidneys and other organs become inflamed. Symptoms include nose bleeds, difficulty ...Read more