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Doctor insights on: Worst Sickle Cell Anemia Symptom

Usually none.: Patients with sca trait usually have no symptoms. If they are in an environment where oxygen is low, like high altitude, it is possible to have a pain crisis like sca patients get, but it is quite rare. ...Read more

Sickle cell trait: Sickle trait means one copy of hemoglobin carries the mutation for sickle cell disease and the other copy is unaffected. Most people with sickle trait are unaffected by this. For athletes with sickle trait, it is essential to keep well hydrated. See http://www.Cdc.Gov/ncbddd/sicklecell/traits.Html for good recommendations. ...Read more

Depends: It depends on the type of sickle cell disease a patient has, and how many attacks they get in a year and how severe those attacks are. ...Read more

Sickle cell Trait: can offer some protective value regarding severity of malarial disease. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..." ...Read more

Pain crisis=painful: Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. ...Read more

Pain.: When red cells sickle, they become rigid and block the flow of blood. If this happens in muscle or bone, the result is pain. In the lung it's pain and shortness of breath. In the brain, it can cause a stroke. Any organ can be effected. A painful crisis happens when blood flow is interrupted. They are episodic and unpredictable. ...Read more

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B(0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B(+)thal: has 60% HbSS and 30% HbA, thus less severe than HbSS (sickle cell alone). HbS/A-thal: less severe than HbSS due to decreased HbSS amount. ...Read more

No: Sickle cell anemia is not an infection - thus it is not contagious. It is a genetic disease and so, it is hereditary. ...Read more

Anemia: The only thing similar is that both have anemia ( decrease level of hemoglobin ). That is all. Sickle cell anemia and aplastic anemia are completely different disorders. Each has different pathogenesis, different clinical manifestation/symptoms, etiologies, treatments etc. ...Read more

Yes: Individuals with sickle cell anemia are at high risk to develop invasive bacterial infections, e.g., meningitis and bacteremia, especially by pneumococcus. Penicillin prophylaxis, immunization, and prompt medical attention for febrile illness have greatly reduced fatality from serious infection. ...Read more

Malaria doesnt cause: Sickle cell anemia is a hereditary disease caused by a mutation in the dna coding for hemoglobin. Scientists have long known that sickle cell anemia protects carriers from malaria infections, which could be advantageous in certain parts of the world. Malaria does not cause sickle cell anemia. ...Read more

Poor circulation: In sickle cell disease red cell stick together and block circulation to extremity and other organ so it cause pain crisis. ...Read more

Hereditary: Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. ...Read more

Pretty common.: 1 in every 500 african-americans, and 1 in every 900 hispanic americans. ...Read more

May be: May be clot but can have chronic pain that likely is scd related. May also be avascar necrosis or dvt. Rec see a md. ...Read more

Yes: Sickle cell crisis typically presents with the predominant symptom of pain. He can typically be in the bone, abdominal pain or pleuritic pain. The skin also be associated with shortness of breath. ...Read more

That number used to : Be in the 30s, but modern supportive care has improved the prognosis. ...Read more

Chronic disease: Sickle cell disease is so significant in that it is a chronic disease that affects almost every organ. Like diabetes, the effects of sickle cell, crises, and transfusions can permanently affect the heart, the kidneys, the liver, the lungs, and the brain. ...Read more

Only here in the US: If you compare a MAP of malaria prevalence (number of cases) to a MAP of sickle cell disease prevalence, they are almost super-imposable with one exception; the United States. The prevalence of sickle cell anemia in the us is as high as some african countries with lower malaria frequencies, but our only malaria comes from travelers. ...Read more