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Doctor insights on: Wilson

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What is wilson's disease?

What is wilson's disease?

Copper accumulation: Wilson's disease is a disorder in which copper accumulates in the body cells. This causes liver disease, psychological changes, and movement disorders similar to parkinsons disease. It can usually be diagnosed by blood and urine tests, but sometimes requires a liver biopsy. It is treated by a low copper diet and medication that reduces copper levels. ...Read more

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What causes wilson's disease?

What causes wilson's disease?

Genes: Wilson's disease is due to mutations in the wilson disease protein (atp7b) gene. Wilson's - konovalov's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues like the liver and cornea; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication and sometimes liver transplant. ...Read more

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Why is wilson's disease found?

Why is wilson's disease found?

Treatable killer: This may be the most treacherous of all diagnoses. 1 in ~60000 people have this defect in copper metabolism that may have no symptoms or look like something else until it ruins the liver and brain. It's picked up on lab testing and even these are fraught with pitfalls. Diagnosed, it's very easy to treat. I wish you luck and hope your workup is done well. ...Read more

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How dangerous is wilson's disease?

How dangerous is wilson's disease?

Extremely: True Wilson's is fatal if neglected, and it is an especially gruesome way to die, with progressive brain damage compounding liver failure. ...Read more

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How do you detect wilson's disease?

How do you detect wilson's disease?

Screen: I suggest a urine copper if there is reason to believe it is present, or if there's strong evidence, go right to the ATP7B gene for sequencing. ...Read more

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Can Wilson's disease effect vision?

Can Wilson's disease effect vision?

Indirectly: the corneal deposits are diagnostic but do not affect your vision other components of the disease con affect your vision indrectly ...Read more

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How can you live with wilson's disease?

Comply: Usually, oral medication with few side effects is enough to keep the illness under control. Neglecting Wilson's leads to a gruesome death, but most of these folks live normal lives on treatment. ...Read more

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Can you explain wilson's disease, please?

Can you explain wilson's disease, please?

Copper overload: Each parent is a carrier and the patient has two defective copies of the atp7b gene, making it impossible to pump copper out of certain cells. Damage to the brain and liver is the most severe, but there is also hemolysis and dysfunction of the proximal kidney tubule. It's missed from time to time with disastrous results; screening labs are famously unreliable. ...Read more

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What are the symptoms of wilson's disease?

What are the symptoms of wilson's disease?

Depends on organ: Affected. Signs and symptoms of wilson's disease include: clumsiness, depression, difficulty speaking, difficulty swallowing, difficulty walking, drooling, easy bruising, fatigue, involuntary shaking, joint pain, loss of appetite, nausea, skin rash, swelling of arms and legs, yellowing of the skin and eyes. Check this site: http://www.Mayoclinic.Com/health/wilsons-dis. ...Read more

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How do I know if I have wilson's disease or not?

Labs: I suggest a urine copper level as a screen. Your physician can do this or can refer you if you have any reason to be concerned. ...Read more

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I think I have wilson's syndrome, what do I do now?

No enough info: if you have a sibling who has been diagnosedwith this condition, you need an evaluation By a physician knowledgeable in this rare autosomal recessive disorder like a metabolic or boochemical geneticist. ...Read more

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Can you live a full normal life with wilson's disease?

Can you live a full normal life with wilson's disease?

Yes: If it is detected early and treated effectively, you can enjoy good life and health . Wilson's disease requires lifelong treatment to reduce and control the amount of copper in the body. ...Read more

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What are the most common symptoms of wilson's disease?

What are the most common symptoms of wilson's disease?

Liver Disease/ Neuro: Untreated wilson disease may manifest as liver disease (toxic hepatitis) in childhood and neurologic problems(tremor, deteriation of school performance, psychiatric isssues) as young adults. ...Read more

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What is the manifestation of wilson's disease in female?

What is the manifestation of wilson's disease in female?

Same as in male: Miss it, and the person becomes unable to move normally, then paralyzed. The liver develops cirrhosis and ultimately fails. There's moderate hemolysis and often a Fanconi syndrome of the proximal tubule. ...Read more

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What is the definition or description of: Wilson's disease?

What is the definition or description of: Wilson's disease?

Wilson's disease: Wilson's disease is a genetic disorder which causes copper to accumulates in body tissues & may cause psychiatric or neurological sx's & liver disease. ...Read more

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Please explain reasons why wilson's disease found in females?

Please explain reasons why wilson's disease found in females?

Unrelated to sex: I'm going to assume you are talking about genuine wilson's hepatolenticular degeneration, not the fad "diagnose-it-yourself" wilson's syndrome. The atp7b gene is on chromosome 13, not a sex chromosome, and it's unrelated to being male or female. ...Read more

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What is the difference between wilson's syndrome and wilson's disease?

What is the difference between wilson's syndrome and wilson's disease?

Phony vs deadly: "Wilson's syndrome" is the invention of an independent medical thinker with no publication on the subject. People are asked to self-diagnosed based on a single low-normal body temperature reading and a huge list of symptoms. Wilson's disease is among the most treacherous illnesses to diagnosed, and if missed, produces a gruesome death. They're very different. ...Read more

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What do you suggest if I have dark rings around irises--wilson's disease?

Maybe: More likely, you're looking too closely at your eyes and at internet pictures. By the time the KF ring appears in the eye, the person with Wilson's is obviously sick -- at least with elevated liver enzymes and probably glucose in the urine. A competent physician will have picked it up. Glad you're health conscious. Best wishes. ...Read more

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Wilson desease can give hbp problems?

Liver: Wilson's disease is a liver condition obviously that can cause hypertension. ...Read more

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