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Doctor insights on: Will Primary Sclerosing Cholangitis Kill Me

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Will primary sclerosing cholangitis kill me?

Will primary sclerosing cholangitis kill me?

Yes: It is a disease that slowly progresses and eventually without treatment leads to hepatic failure which has a very high mortality rate. ...Read more

Dr. Michael Gabor
32 doctors shared insights

Primary Sclerosing Cholangitis (Definition)

Primary sclerosing cholangitis (psc) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is ...Read more


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How can I treat primary sclerosing cholangitis?

How can I treat primary sclerosing cholangitis?

Difficult problem: Psc: autoimmune swelling/scarring of bile ducts within and outside the liver; often associated with infl. Bowel (usually ulc colitis). Increased risk for biliary ca. Med rx for itch, biochem abnormalities, e.g. Urso (bear bile), antihistamines, antibiotics for infections, vitamin supllements for deficiencies. Ercp procedure may open some strictures (narrowing). Ultimately, may need liver transpla. ...Read more

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What is the definition or description of: primary sclerosing cholangitis?

What is the definition or description of: primary sclerosing cholangitis?

PSC: Primary sclerosing cholangitis (psc) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is believed to be autoimmunity. ...Read more

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Do people with primary sclerosing cholangitis have a lot of pain?

Do people with primary sclerosing cholangitis have a lot of pain?

Depends: Primary sclerosing cholangitis ( psc) causes destruction of the bile ducts inside and outside of the liver. The first symptoms of the disease include fatigue, itching and jaundice, or yellowing of the skin and eyes. Psc however, is associated with a number of hepatobilliary disorders like pancreatitis, which may cause pain. ...Read more

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I'm a 25 year old male recently diagnosed with stage 2 primary sclerosing cholangitis. Is this a common age range for this issue?

Sorry to hear: Primary sclerosing cholangitis tends to occur more frequently in males than women and onset may be between 20-30yrs old. Sometimes it is isolated, other times it may be associated with other diseases such as ulcerative colitis. Hopefully, you are seeing a hepatologist at a local university hospital, who can discuss possible treatments w/ you. Stay positive and god carry and bless you! ...Read more

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Primary sclerosing cholangitis---what treatments are best?

Depends: On stage. Usually it has poor response to chronic meds, and antibiotics are used for superimposed infections in times of flare ups. ...Read more

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Is primary sclerosing cholangitis rare?

Is primary sclerosing cholangitis rare?

Yes: The goal of managing acute attacks is antibiotics and IV fluids. In about 15%, emergency decompression or surgery is needed. Prevention of future attacks of cholangitis is based on removing biliary stones and debris, dilation or resection of strictures, and establishing optimal biliary drainage. Also important to rule out the clonorchis parasite. Your GI doctor can discuss newest treatments. ...Read more

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Primary sclerosing cholangitis, what is this like??

Bile duct obstructio: Idiopathic (probably autoimmune) progressive scarring and narrowing of the bile ducts. May need surgical intervention or transplant This reference may help: http://www.mayoclinic.org/diseases-conditions/primary-sclerosing-cholangitis/basics/definition/CON-20029446 ...Read more

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Could you explain what is primary sclerosing cholangitis?

Bile duct scarring: Primary sclerosing cholangitis (psc) is an inflammatory disease of the bile ducts that causes scarring and subsequent obstruction of bile ducts inside and/or outside the liver. This blocks the flow of bile to the gut, which can ultimately lead to cirrhosis of the liver. The underlying cause of psc is not entirely known, but believed to be an auto-immune disorder with a strong association with uc. ...Read more

Dr. Heidi Fowler
69 doctors shared insights

Cholangitis (Definition)

It is an infection of the bile ducts. Usually there is an obstruction of the bile ducts. Most commonly this is caused by a gallstone, although there are other rarer causes. It can be life threatening. If you have pain in your right upper quadrant, a fever and are jaundiced, ...Read more


Dr. Bernard Seif
27 doctors shared insights

Sclerosing Cholangitis (Definition)

It is an inflammatory condition of the main bile duct that drains bile from the liver. It is important to follow with an experienced gastroenterologist because untreated, the condition can ...Read more