Doctor insights on:
Will Estrogen Cause Uterine Cancer
No, a risk factor: Unopposed estrogen is a risk factor for uterine cancer but it does not always cause it. Unopposed estrogen means it is given without any Progesterone another female hormone. Somewhere between 4-8 out of every 1000 women receiving unopposed estrogen per year will get uterine cancer. Being obese probably makes the risk closer to 8/1000, whereas in thin women the risk is about 4/1000. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Estrogen/Uterine CA: Absolutely not. "high" estrogen levels are only one factor in the risk profile for uterine cancer, which also includes obesity, family history, and oral contraceptive history. Even if you possess one or more risk factors, that does not mean that a tumor is certain. Close monitoring and counselling by your gyn is the best course of action. ...Read moreSee 1 more doctor answer
What is the link between estrogen and uterine cancer? Is there a link between estrogen and developing uterine cancer?
Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more
It is an option: The Mirena (levonorgestrel) can counteract or balance the estrogen from patches to prevent uterine cancer but the clinical data for this is limited. Everyone's situation is different but it is an option to discuss with your gyn. Here is a reference on pubmed.gov Climacteric. 2011 Dec;14(6):622-32. Copy and paste that and you will see the study. ...Read more
Should I lower BMI from 20 to 19 to lower estrogen? Had uterine cancer and hysterectomy. Kept ovaries. Afraid of breast/ovarian cancer.
No: Your BMI is normal. What stage/grade was your uterine cancer? Is there a family history of breast/ovarian cancer? Your surgeon may be able to provide you with information regarding these risks, may be able to order cancer genetics screening tests if indicated, or may be able to refer you to a cancer genetics counselor should you choose to do so. Best Wishes ...Read more