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Doctor insights on: Will Cytoxan Prednisone Fertility

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Will taking cytoxan (cyclophosphamide) and prednisone decrease my fertility?

Will taking cytoxan (cyclophosphamide) and prednisone decrease my fertility?

Yes: Cytoxan (cyclophosphamide) can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan (cyclophosphamide) is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more

Dr. Thomas Namey
2,560 doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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Will deltasone (prednisone) increase testosterone?

Will deltasone (prednisone) increase testosterone?

Not likely: Deltasone is a brand of prednisone. It is a corticosteroid which is much different than an anabolic or androgenic steroid. Taking Deltasone when you don't need it (and sometimes even if you do need it) can cause high blood pressure, diabetes, thin skin, obesity, cataracts, ulcers and many other problems. ...Read more

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After cytoxan (cyclophosphamide) (chemo therapy), how quickly can you begin in-vitro fertilization?

After cytoxan (cyclophosphamide) (chemo therapy), how quickly can you begin in-vitro fertilization?

IVF specialist : Hi you need to wait for the drug to be cleared from you system- ultimately your oncologist and ivf specialist together should help you make that decision. ...Read more

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How much does taking weekly humira (adalimumab) injections lower my immune system?

How much does taking weekly humira (adalimumab) injections lower my immune system?

Not definitive: It lowers resistance, but unclear how much. Essential is avoiding infectious exposure. Avoid individuals who have had live vaccines - for 30 days after vaccination. ...Read more

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Will predinsolone steroid affect microgynon 30?

Will predinsolone steroid affect microgynon 30?

Other way around: B"sd it is always a good idea as indeed certain medications can decrease the effectiveness of oral contraceptive pills. Prednisone /prednisolone is not one of them. On the other hand OCP pills decrease the clearance prednisone and therefore result in higher blood levels, which may or may not be a problem depending on the condition being treated and duration of use. ...Read more

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Taking an hCG and B12 injection. How will it effect me?

Taking an hCG and B12 injection. How will it effect me?

Less: Do not take the HCG at the same time with or together with the b12, as you may experience less efficacy of the hcg. This is just anecdotal. Just take the B12 on a diff day. ...Read more

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Can high dose solumedrol (methylprednisolone) treatment affect male fertility? Please explain.

Can high dose solumedrol (methylprednisolone) treatment affect male fertility? Please explain.

Steroid side effects: Even high dose solumedrol (methylprednisolone) is not known to cause infertility. Other immunosuppressives can cause infertility. Why do you receive this treatment? The underlying cause or disease process you might have could also cause this. Need to check in with the doctor giving you solumedrol (methylprednisolone). ...Read more

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Can adding hCG shots while taking femara (letrozole) for infertility improve the chances of conceiving?

Can adding hCG shots while taking femara (letrozole) for infertility improve the chances of conceiving?

Sometimes: A properly-timed HCG shot can be used as a 'trigger' for ovulation. Women who develop a dominant follicle with Femara (letrozole) but don't ovulate appropriately (or at all) can be triggered with hcg. ...Read more

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Can the medications typically taken for ulcerative colitis (remicade, 6mp) effect male infertility?

Can the medications typically taken for ulcerative colitis (remicade, 6mp) effect male infertility?

Perhaps: Infliximab may decrease sperm motility and the number of normal oval forms. Whether these changes translate into impaired fertility is unknown. 6mp has been rarely associated with birth defects even when the father takes the medication. The benefits, however, often outweigh the risks and you need to discuss this with your doctor. ...Read more

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Will taking cytoxan (cyclophosphamide) and prednisone decrease my fertility?

Yes: Cytoxan (cyclophosphamide) can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan (cyclophosphamide) is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more

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If a man is on chronic prednisone, does that decrease his fertility?

If a man is on chronic prednisone, does that decrease his fertility?

It could: Most people on long-term steroids have a significant illness and thus either the disease or the medication could affect fertility. The good thing is that checking a man's fertility potential is one of the easiest parts of the fertility examination and one of the least expensive! ...Read more

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Can a low dose (5mg) of prednisone (prescribed to reduce mild adrenal hyperplasia to improve female fertility) aggravate my depression?

Can a low dose (5mg) of prednisone (prescribed to  reduce mild adrenal hyperplasia to improve female fertility) aggravate my depression?

Yes it can: Yes, Prednisone can aggravate depression. Please discuss this with your physicians. Dose adjustments may be needed in your prednisone, your antidepressants, or both. If feeling depressed but not yet being treated for depression, an evaluation could help discern what's going on. Effective treatment could be provided. ...Read more

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My obgyn prescribed glucophage, prednisone, and Synthroid (thyroxine) (for TSH levels) to help increase my fertility. I'm 38 & ttc for 7 months. Will this help me?

My obgyn prescribed glucophage, prednisone, and Synthroid (thyroxine) (for TSH levels) to help increase my fertility. I'm 38 & ttc for 7 months. Will this help me?

Depends: Presumably, the medications are being prescribed to address specific conditions to either improve chance of conceiving and/or chance of having a healthy pregnancy. Glucophage is usually prescribed in women with glucose intolerance/insulin resistance (common in pcos). Synthroid (thyroxine) is prescribed for thyroid supplementation in hypothyroidism. Important however that full infertility evaluation be done. ...Read more

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What does it mean to have a suppressed immune system? e.g the immune system was suppressed by Prednisone? Does it mean that you have to avoid people?

Prednisone: Prednisone does suppress the Immune system. However it depends on how much and for how long. As a rule within 2 to 4 weeks your immune system should bounce back to normal. People on prednisone or recovering from being on prednisone usually do no have to avoid people. ...Read more

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Can prednisone stunt my growth?

Can prednisone stunt my growth?

Prednisone: If you are 50 you have stopped growing and indeed likely shrinking in height. Prednisone may causes vertebral collapse if used for long time at high dose. Lets do 2nd opinion. ...Read more

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How does prednisone affect your mood?

Euphoric grouch?: Prednisone can cause euphoria, agitation, insomnia, mania (especially in bipolar sufferers), psychosis, confusion, hunger, depression and anxiety. Many initially feel very energetic and get a lot done, then exhausted and depressed when it is stopped. Often patients tell me they think they are fine but their families find them short-tempered. Side effects are dose and duration-related; temporary. ...Read more

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What medicine can replace prednisone?

Depends on disease: If you are asking what other similar medications (steroids) can be used there are several options such as medrol (methylprednisolone). If you are asking can you stop steroids completely and substitute another treatment - this is often but not always possible. It depends on your diagnosis. I suggest you discuss this with your doctor. ...Read more

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Can prednisone treat a puffy uppereyelid?

Sometimes: If it is due to an allergic reaction or a bug bite, it can. If it is secondary to an infection, do not use it. ...Read more

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Who should not take Deltasone (prednisone)?

Deltasone (prednisone): Deltasone (prednisone) is contraindicated with "Systemic fungal infections and known hypersensitivity to components." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3400d26a-41cb-40e4-99b4-780e1e0ec561 ...Read more

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If I overdosed on prednisone last night, can I die?

If I overdosed on prednisone last night, can I die?

Unlikely!: Best bet is you did not sleep. We use doses of methyprednisolone or Dexamethasone at doses equivalent to 1000mg of Prednisone by IV administration to treat severe flares in lupus, or to sometimes treat vasculitis. I doubt you took so much. ...Read more

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I can't stop the prednisone. Should i take metformine?

Take what is Rx'd: Obviously your details are limited. If you are diabetic, or otherwise have Insulin resistance and are taking a steroid, your blood sugars will typically go up. If your doctor has prescribed metformin to address this, then by all means take it. If you have not been prescribed or otherwise instructed to take metformin, then talk to your doctor before doing so. ...Read more

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How can I reduce my appetite while being on prednisone?

Prednisone hunger: One option is to reduce the dose of prednisone. In some people using the comparable medication, methylprednisolone, has less of this effect. When you do eat, eat high fiber, high water foods to fill you without as many calories. ...Read more

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Can medications like prednisone be taken with alchohol?

Yes, but...: While on prednsone drink little or very moderately. Why? Prednisone makes the lining of the stomach much more vulnerable to any irritant, which includes etoh (alcohol). Dilute beverages are much preferred like beer. But not much, since both agents can cause gatritis and GI bleeding. ...Read more

Dr. Khurram Rehman
1,639 doctors shared insights

Fertility (Definition)

Fertility refers to the ability of a woman to conceive a child, or to the ability of a man to ...Read more


Dr. John Feola
991 doctors shared insights

Liquid Pred (Definition)

Liquid Pred is a corticosteroid which is a kind of ...Read more