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Doctor insights on: Why Would My Doctor Order An Endometrial Biopsy Is That A Cancer Test

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Dr. Barry Rosen
4,341 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Had endometrial biopsy. Doc said no cancer was found but it showed "disorganized cells". Waiting for gyn call. What does disorganized mean? What do?

Had endometrial biopsy. Doc said no cancer was found but it showed "disorganized cells". Waiting for gyn call. What does disorganized mean? What do?

Not entirely normal: Unless we can see the formal pathology report, it is hard to tell exactly what it means. When cells are not entirely normal in their appearance or orderly in their location/organization, you will see such a report. It simply means to recheck them again in the future so that your doctor can keep an eye on the observed changes which can either settle down with time or rarely, progress to cancer. ...Read more

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I have slight pinkish discharge after intercourse married and no stds. Doc has done endometrial biopsy and ecc, pap and HPV test all ngtv then why?

I have slight pinkish discharge after intercourse married and no stds. Doc has done endometrial biopsy and ecc, pap and HPV test all ngtv then why?

Probably normal: First of all, it was a great idea to have this checked out. Pinkish discharge, or spotting, can have a serious cause. But since all your tests were normal, the symptom is probably normal for you. It may be due to a bit of trauma with the skin inside the vagina being irritated during intercourse. If there are spermicidals or other fluids, even semen, then the discharge is diluted -- pinkish. ...Read more

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Endometrial Cancer. Endometrial biopsy normal, lining is at 15. What does this mean?

Endometrial Cancer. Endometrial biopsy normal, lining is at 15. What does this mean?

I don't: Understand: do you have endometrial cancer? Then the lining and the biopsy are irrelevant. Are you be tested for endometrial CA? The normal biopsy is reassuring, the thickness is not specific. Glad to give a better answer if you clarify what you are asking. ...Read more

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After an endometrial biopsy comes back negative for hyperplasia/cancer. What's the chance of a D&C showing cancer a month later?? Also have a polyp

After an endometrial biopsy comes back negative for hyperplasia/cancer. What's the chance of a D&C showing cancer a month later?? Also have a polyp

Always a chance: The possibility does exist that a cancer could not have been sampled. Sampling is done in a systemic fashion to lower the chances of it. ...Read more

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Had an ultrasound done, came back clear, doing an endometrial biopsy to determine precancerous cells. Is there a chance I have full blown cancer?

Had an ultrasound done, came back clear, doing an endometrial biopsy to determine precancerous cells. Is there a chance I have full blown cancer?

Need more info: Are you saying that an endometrial biopsy is being done because of a question of premalignant cells on a Pap smear? If so, an endometrial biopsy should help to clarify that. With a normal ultrasound, it is unlikely that you have "full blown" cancer but the biopsy is important. ...Read more

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How accurate is an office hysteroscopy endometrial biopsy &polypectomy in showing cancer or hyperplasia?

How accurate is an office hysteroscopy endometrial biopsy &polypectomy in showing cancer or hyperplasia?

Not entirely -: To make these diagnoses - of cancer and hyperplasia - a pathologist really must examine slides of biopsies or smears. These diagnoses cannot be made with any certainty without microscopic examination. ...Read more

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Possible Endometrial cancer. Endometrial biopsy normal. Hysteroscopy D&C recommended because lining is 15. What is this suspect of?

Possible Endometrial cancer. Endometrial biopsy normal. Hysteroscopy D&C recommended because lining is 15. What is this suspect of?

Endometrial polyp: If the biopsy was negative, chances are minimal that you have cancer. Most likely, you have a polyp causing the thickened endometrium. The hysteroscopy and D&C will show what is definately going on and allow removal of the tissue. It will also confirm the biopsy results, likely showing no cancer. ...Read more

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History of lynch syndrome. Sisters endometrial biopsy said limited tissue available, but benign. Should it be redone to rule out cancer if symptomatic?

History of lynch syndrome. Sisters endometrial biopsy said limited tissue available, but benign. Should it be redone to rule out cancer if symptomatic?

Lynch syndrome: Lynch syndrome is an inherited condition that increases your risk of colon cancer and other cancers including endometrial cancer in women. If your sister is symptomatic and does have Lynch syndrome a suboptimal biopsy is not sufficient to rule out endometrial pathology. Further workup is warranted. ...Read more

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If had endometrial biopsy w/ office hysteroscopy for thick lining path came back normal been on progesterone for 7 months could be cancer now?

If had endometrial biopsy w/ office hysteroscopy for thick lining path came back normal been on progesterone for 7 months could be cancer now?

Unlikely: Alot depends on your biopsy diagnosis. If it wasjust a thickened lining, and no evidence of hyperplasia, and you were treated with Progesterone for 7 months, a maligancy would be very unlikely. ...Read more

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Why would my doctor prefer an endometrial biopsy?

Why would my doctor prefer an endometrial biopsy?

More info?: Typically we like to do the one procedure that will give us the most complete information. ...Read more

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Doctor ordered endometrial biopsy, should I be worry?

Doctor ordered endometrial biopsy, should I be worry?

No always worrysome: If doctor ordered endometrial biopsy, he/she wants to understand the cause of your symptoms and you have appropriate treatment.
It does not mean you have abnormal result. Be strong and follow doctor's instructions. ...Read more

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What does it mean when the doctor sends you for an endometrial biopsy?

Varies: It would depend on what symptoms you had. Endometrial biopsy may be done to investigate fertility, assess precancerous and suspected cancerous lesions. ...Read more

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I am supposed to have an endometrial biopsy and my doc said since I have had six children it won't hurt badly, is that accurate?

Probably true: Pain during an endometrial biopsy varies with some patients feeling none and some feeling cramping. Having had six children your cervix will be more open than others making the biopsy easier and smoother. Likely you would feel less than most people for that reason. ...Read more

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Can doctors do an endometrial biopsy when you have period?

Yes: There are a few exceptions for infertility cases but for the most part it does not matter if you are still bleeding at the time of endometrial biopsy. In fact, the cervicl os or opening of the cervix is more open than usual making the biopsy slightly easier. ...Read more

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My doctor attempted to do an endometrial biopsy and had to stop because it was very painful. What are the alternative options I have to to get this d?

My doctor attempted to do an endometrial biopsy and had to stop because it was very painful. What are the alternative options I have to to get this d?

Sonogram or sedation: A pelvic sonogram performed by a certified skilled sonographer or a saline sonohysterogram may help decide if an endometrial sampling is really necessary. If your endometrium is "thickened", an office procedure under sedation or paracervical anesthesia is an "alternative option"; otherwise you may need a dilatation of your cervix in an OR or ambulatory surgical unit served by an anesthesiologist ...Read more

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Immense pain with endometrial biopsy now doc wants me to have novasure with no sedation. Just local anesthetic. Should I worry? As I am.

Immense pain with endometrial biopsy now doc wants me to have novasure with no sedation. Just local anesthetic. Should I worry? As I am.

Mild sedative/driver: Ask your doctor for a prescription for ativan, for example to take prior to the procedure or take benadryl (diphenhydramine) beforehand if it makes you sleepy and have someone drive you to and from. ...Read more

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58 year old woman with 7 CM endometrial lining, stopped HRT therapy 3 months ago. Endometrial biopsy recommended by doc with d&c or hysterectomy?

Hysteroscopy/ D&C: If you are having postmenopausal bleeding then a hysteroscopy with a D&C is appropriate. About 10% of postmenopausal bleeding may be attributed to cancer. However since you were on hrt, sometimes it can take up to 6 months for bleeding to stop. Given your history that your bleeding (assuming you are having this) the likelihood that it's due to hrt or endometrial polyp is more common than cancer. ...Read more

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I had an endometrial biopsy & a IUD inserted. I'm a virgin so I'm positive my Doc. Broke my hymen. If I have Sex will it hurt?? will my hymen grow back?

I had an endometrial biopsy & a IUD inserted. I'm a virgin so I'm positive my Doc. Broke my hymen. If I have Sex will it hurt?? will my hymen grow back?

It doesn't: The pain with first sex idea is overdone. If a woman has a healthy vulva and vagina; if she is very stretchy; if she is happy and relaxed, with lots of natural lubrication; if a guy enters at a good angle, at the right spot; if he moves with small motions until she is well-lubricated and stretched out; there may not be hymen tearing nor bleeding. Ignore the hymen, as it should be of no relevance. ...Read more

Dr. Cornelius O'leary jr
2 Doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


Dr. Deepali Kashyap
164 Doctors shared insights

Endometrial Biopsy (Definition)

Endometrial biopsy: a common procedure for sampling the inner lining of ...Read more