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Doctor insights on: Why Would I Have High B12 Levels In My Blood

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A blood test showed that I'm B12 deficient. Serum B12 level of 186 pg/ml, should I take vitamin B12 supplements?

A blood test showed that I'm B12 deficient. Serum B12 level of 186 pg/ml, should I take vitamin B12 supplements?

B12: This low will likely cause dementia, spinal cord degeneration and peripheral neuropathy. Keep your level above 550 for the rest of your life. Recovery takes about a year in a young person. I suggest you take liquid sublingual weekly for 3 months then bi weekly thereafter. Its important to check a level after you cut back to twice a month. Use 1 1/2 dropper and hold it under the tongue for 30 sec. ...Read more

Dr. Randy Baker
1,010 Doctors shared insights

Vitamin B12 (Definition)

Vitamin B12 is a vitamin which is a kind of nutritional agent ...Read more


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Why would I have high B12 levels in my blood?

Why would I have high B12 levels in my blood?

High intake: Since vitamins, by definition, are substances that we cannot make ourselves, a high level can only come from high intake. Vitamin B12 is not very toxic, but in high amounts can cause diarrhea, edema and increase risk of clots. If you are taking a vitamin B12 supplement, or injections you may want to cut back (discuss with your doctor if you are taking under a doctor's supervision). ...Read more

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Is a blood B12 level of 1400 too high?

Is a blood B12 level of 1400 too high?

No: It is higher than the lab reference range, but it is fine and nothing to worry about. ...Read more

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In my last blood test, I have high levels of B12 (950mg). What this mean?

In my last blood test, I have high levels of B12 (950mg). What this mean?

There is no: Consequence of an elevated B12 level. It is a water soluble vitamin. ...Read more

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Can dehydration cause high levels of B12 in blood?

Can dehydration cause high levels of B12 in blood?

No: Chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of B12 mostly from increased production of haptocorrin.
In addition, because the liver stores b12, liver diseases such as acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also cause a rise in serum b12. ...Read more

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What would it point to if urine homocysteine levels are high and chronic high b12 levels for years? Blood homocysteine is normal.

What would it point to if urine homocysteine levels are high and chronic high b12 levels for years? Blood homocysteine is normal.

Means nothing: This pathologist thinks the whole homocysteine business is a fad driven by fear of liability. Nobody knows what to do with the data, beyond advising healthy lifestyles. High B12 reflects the fact that you make mirror the binder protein than other folks. It's you. Stay physically fit and be thankful for good health. ...Read more

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What causes a high B12 blood level. My doctor said I am at 902. Not significantly high.

What causes a high B12 blood level. My doctor said I am at 902. Not significantly high.

Meat intake?: B12 comes mostly from meat and liver. You might have a high meat intake or maybe your body is efficient at absorbing it. Its good to have B12 since you need it to make red blood cells. There is no harm to what you described. ...Read more

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What blood disorders/disorders can cause elevated B12 levels and low iron?

What blood disorders/disorders can cause elevated B12 levels and low iron?

Polycythema vera: Some times polycytemia vera can cause, but rare, this needs further work up, especially low. Iron that is most of the time due to bleeding. ...Read more

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If my kidneys and liver are ok and my blood is 46.Why I would have a very high level of B12 in my blood. Is it because I took difen B12 from 8 months?

Gene mutations: You could have gene mutations that are interfering with the methylation pathways causing an inactivated from of b-12 to accumulate in your blood. Mthf and cbs are the genes that can be mutated causing this effect. ...Read more

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If B12 levels are high >1999, and red & white blood levels are normal, should I be concerned about Leukemia? B12 supplements were stopped 3 weeks ago.

If B12 levels are high >1999, and red & white blood levels are normal, should I be concerned about Leukemia? B12 supplements were stopped 3 weeks ago.

No: There's a fairly common form of leukemia in which B12 tends to go up. If your CBC is normal, you can be as confident that you do not have this particular form of leukemia as you can be confident you are not pregnant. Relax, friend. Everybody has a few labs out of range. You'll simply make your life harder than it already is if you let this stuff bother you. Be glad for good health. ...Read more

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Had bloods done I've got high folate (folic acid) levels of 20:1 what does this mean I'm male b12 & hemoglobin are OK?

Had bloods done I've got high folate (folic acid) levels of 20:1 what does this mean I'm male b12 & hemoglobin are OK?

Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, Serum folate (folic acid) level of 20.1 is perfectly normal and is not a cause for any concern. ...Read more

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Are elevated B12 and folate (folic acid) levels a problem? My most recent blood work showed these both to be high...Any danger?

Are elevated B12 and folate (folic acid) levels a problem? My most recent blood work showed these both to be high...Any danger?

How high?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual values of the results. In general high values for folate and B12 are not a problem. ...Read more

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I did blood test for B12 vitamin and the result was 1617 and the normal level is 700.I need to know why is it to high and what are the risks?

I did blood test for B12 vitamin and the result was 1617 and the normal level is 700.I need to know why is it to high and what are the risks?

Needs evaluation: I am sorry to tell you that high B12 levels can be a sign of serious health problems including liver ; kidney disease, myelproliferative disorders including leukemia ; polycythemia vera ; hypereosinophilic syndrome. High intake of B12 does not cause these. It is important for you to be evaluated to find the underlying cause. See http://healthyeating. Sfgate. Com/high-vitamin-b12-mean-9057.Html. ...Read more

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Hi I have hashimoto disease. Will this cause a low B12 level or a high white blood count?

No: Hashimotos will not directly lower your B12 level or elevate your white count. ...Read more

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My 6yr old daughter had her blood work done which reports high Vit B12 level @ 1186 pg/mL. Not on any supplements, has vitiligo, is this a concern?

My 6yr old daughter had her blood work done which reports high Vit B12 level @ 1186 pg/mL. Not on any supplements, has vitiligo, is this a concern?

No: This means nothing. Reference ranges are set so that a few percent of healthies are over the top. This is just a little extra carrier protein shuttling the vitamin around. ...Read more

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My 6yr old daughter had her blood work done which reports high Vit B12 level @ 1186 pg/mL. Not on any supplements, has vitiligo, is this a concern?

My 6yr old daughter had her blood work done which reports high Vit B12 level @ 1186 pg/mL. Not on any supplements, has vitiligo, is this a concern?

Very high level: The abnormal lab value needs to be further addressed. Can be caused by increase in the blood protein that carries B12 (made by blood cells), or liver or kidney problems. If basic labs for liver/kidney are normal, the next step is to screen for problems related to the bone marrow and blood cell production or for inflammatory disorders. Vitiligo (autoimmune attack of pigmented cells) could explain. ...Read more

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Very high B12 blood level, low iron, rt side ab pain despite very strict gfdiet for celiac disease, not on vitamins. What could cause high B12 levels?

High B12 and folate (folic acid): Levels are caused by their accumulation and non use in the body. I have seen it related to vitramin b1 deficiency. Worth trying. ...Read more

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What can cause high Active (holotranscobalamin) B12 levels in blood, when red & white cell & platelet counts, liver & kidney function are all normal?

It's just you: This test itself is not mainstream. It is experimental. A high value on a B12 is never a clinical concern. Reference ranges at real labs are set so that a few percent of healthy folks fall outside on either end. ...Read more

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I have constant pelvic and left leg tingling. Low vitamin d and b12, high fettrin levels and slightly high csf. Mri's neg, blood ok. Thoughts?

I have constant pelvic and left leg tingling. Low vitamin d and b12, high fettrin levels and slightly high csf. Mri's neg, blood ok. Thoughts?

Sciatica plus?: You have described different complaints plus test results, some confused: what is "high csf"? Was the MRI a spine study? Pelvic pain and leg pain sound like a spine problem. See a neurologist who specializes in nerve and muscle disease. Ask about nerve conduction tests. ...Read more

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What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

Dietary supplents: The most likely cause of elevated B12 and folate (folic acid) is dietary or parenteral supplements. Other sources of B12 and folate (folic acid) are the diet itself. Consult your doctor for more information. ...Read more

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What does high B12 in blood mean when really high?

What does high B12 in blood mean when really high?

Needs evaluation: B12 is not toxic so high B12 due to taking it is not bad. If someone has high B12 without taking it then it can be a sign of serious problems including liver & kidney disease, myelproliferative disorders including leukemia & polycythemia vera & hypereosinophilic syndrome. High B12 does not cause these but caused by them. Further tests are needed to find the underlying cause: http://bit. Ly/1hVpCY7 ...Read more

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I just found old blood work I noticed my B12 says 1267. I know that is really high. What could be the cause. Dr never told me about it last yr?

Not a problem: I'm going to assume that your other labs are unremarkable. Some folks makes extra B12 binding protein. Nobody really understands why. Don't worry about it. ...Read more

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I have a B12 level of 150, the dr tested my bloods to see I'm absorbing the foods and I am so he's gave me 1mg tablets. Is this enough?

I have a B12 level of 150, the dr tested my bloods to see I'm absorbing the foods and I am so he's gave me 1mg tablets. Is this enough?

Should be, however..: Yes, while 1 mg doesn't sound like much, there is a limit as to how much you can absorb at once so more won't help. I advise the methylcobalamin form. Chewing it ; taking on empty stomach should help. Recheck levels in 2-3 months to make sure they're rising- goal is 500 or more.
See http://bit. Ly/1cbhjvn
; http://bit. Ly/1607tg3
; http://bit. Ly/jxwxd2. ...Read more

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Please tell me what would cause a lower B12 and high red blood count?

Wrong approach: Labs mean nothing in isolation. I'm going to assume that you feel well. If you're a vegetarian, a low B12 is a serious warning to reconsider what you're doing to yourself and/or to supplement as vegetarians must. Otherwise, it warns of possible pernicious anemia or other illnesses. A high red count in the absence of high Hgb/Hct often means thalassemia minor. Your physician's your guide. ...Read more