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Doctor insights on: Why Multinodular Goiter Is Dangerous

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What is a multinodular goiter?

What is a multinodular goiter?

Large thyroid lumps: A 'goiter' refers to an enlarged thyroid gland. A multi-nodular goiter is usually diagnosed on an ultrasound scan when many lumps or 'nodules' are seen. Typically these are benign. 3 things to consider for nodular goiter: 1) big enough overall to cause problems with swallowing, voice, or breathing? 2) do nodules over-produce thyroid hormone? 3) are any of the larger or irregular nodules cancer? ...Read more

Dr. Steve Martinez
314 Doctors shared insights

Thyroid Enlargement (Definition)

Thyroid enlargement refers to a thyroid gland that is larger than normal. The thyroid gland is located in the front of the neck, below the Adam's apple, and may become enlarged due to hyper or hypo-thyroidism. An enlarged thyroid is also ...Read more


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How is the diagnosis of multinodular goiter made?

How is the diagnosis of multinodular goiter made?

Exam or ultrasound: Sometimes the diagnosis can be made on the basis of the physical examination alone; in other cases an ultrasound of the thyroid may be required to demonstrate the multi nodular nature of the gland. ...Read more

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I have a multinodular goiter and thyroiditis, what are the chances of it being cancerous?

I have a multinodular goiter and thyroiditis, what are the chances of it being cancerous?

7% to17 % chance: Most of the multinodular goiters are benign but may associated with occult (hidden) cancers in 7 to 17% cases, treating by early detection will cure. ...Read more

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Is multinodular goiter preventable?

Unknown.: Unfortunately, the reasons for nodule development in the thyroid gland are not well understood. ...Read more

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How to shrink multinodular goiter without surgery?

How to shrink multinodular goiter without surgery?

Goiter/FNA: The cause of your goiter determines the possible therapies and yes it can be treated medically. Overall size, compression, response to medical therapy, fna biopsy, cancer are important so work with your team of docs. A surgery consult can give you lots of information about the risk/benefit of therapy with surgery. You have choices, good luck. ...Read more

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Her ultrasound says it's a multinodular goiter. What is that?

Her ultrasound says it's a multinodular goiter. What is that?

See below: Goiter is an enlargement of the thyroid gland. The gland can be generally enlarged or have multiple growths (nodules) leading to enlargement of the whole thyroid gland. The latter is termed multinodular goiter. The nodules are generally benign (noncancerous). The ultrasound appearance is correlated with how well the thyroid works using blood tests of thyroid function. ...Read more

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What is the best way to treat toxic multinodular goiter?

Options: The "best" way will depend on your current clinical, and social circumstances. Your options include1) antithyroid pill to control the thyroid level, 2)radioactive iodine and 3) surgery. Choice 2 and 3 are considered curative options but you need to discuss the pros and cons of these options with your own physician who knows you best. Good luck. ...Read more

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What are the risks associated with a 2nd surgery for a moderate multinodular goiter?

What are the risks associated with a 2nd surgery for a moderate multinodular goiter?

Risk of redo surgery: Second surgery or redo surgery carries increased risk because your surgeon is going through scarred tissue instead of normal anatomy. Typically the surgeon goes slower and small structures like nerves and parathyroid glands are a bit more difficult to identify. Risk depends on the first surgery. If you had one side/lobe removed and now need the other side removed, redo risk does not apply. ...Read more

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I'm wondering are hashimoto's disease and multinodular goiter linked together?

They Can Be!: Whenever the thyroid is under an autoimmune attack, the possibility of developing a multinodular goiter is significantly increased. Whether the goiter and nodules are from Hashimoto's or not, they need to be addressed and appropriately treated. ...Read more

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My son has a nontoxic multinodular goiter, the tyroid is functioning but the antibody tpo are higher than 1000.Should he just be monitored?

My son has a nontoxic multinodular goiter, the tyroid is functioning but the antibody tpo are higher than 1000.Should he just be monitored?

Yes: It would be prudent to consult an endocrinologist to ascertain the frequency of visits and tests. He is at risk of thyroid function disorder. ...Read more

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Can size of thyroid multinodular goiter be reduced?

Can size of thyroid multinodular goiter be reduced?

Maybe: If you treat with levothyroxine, lowering the tsh, the goiter may shrink. But often it does not, at least not much. There is also a risk of inducing hyperthyroidism. If there is a cyst, aspiration of the cyst may shrink the gland, but the fluid in the cyst often comes back. If the goiter is big and compressing airway or esophagus, surgery may be needed. ...Read more

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How is thyroid ultrasound used to diagnose a multinodular goiter?

How is thyroid ultrasound used to diagnose a multinodular goiter?

Sonar images: Ultrasound uses the variation in the 2 dimensional images produced by scanning the thyroid like a fisherman uses sonar to find a school of fish under his boat. Enough thyroid us's have been done to develop pictures of how big each part of the gland should be at a given age in a given condition. ...Read more

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Normal Tpo Ab and Tg Ab; no Hashi's or Graves'. Have a multinodular goiter & Hypothyroidism. If not Hashi's, what causes my Hypothyroidism? Pituitary?

Normal Tpo Ab and Tg Ab; no Hashi's or Graves'. Have a multinodular goiter & Hypothyroidism. If not Hashi's, what causes my Hypothyroidism? Pituitary?

No autoimmune: So your multi nodular is is under production of Thyroxine no on immune basis, must see an endocrinologist to follow nodular goiter is it is cold or hot by Biopsy and follow as appropriate and tsp levels and t3, (liothyronine)t4 ...Read more

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Solid hypoechoic heterogeneous nodule. 2.5cm & 1.5 cm. Multinodular goiter. No dominant nodule wasn't cold or hot what does this mean?

Needle biopsy: It sounds like you've had a thyroid ultrasound and a thyroid uptake scan. Most thyroid nodules are not cancerous, but it's recommended that nodules that look suspicious or larger than a certain size get a needle biopsy. Also called a fine needle aspiration. ...Read more

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I have a multinodular goiter, biggest nodule 1cm/exophytic. Repeat US in 6 months. Did not suggest aspiration. Should I worry about malignancy?

I have a multinodular goiter, biggest nodule 1cm/exophytic. Repeat US in 6 months. Did not suggest aspiration. Should I worry about malignancy?

Malignancy: No you should not worry about malignancy unless you really think something is wrong with your thyroid.
It is difficult to feel comfortable about your goiter unless you get more complete information from your doctor.
Please keep me informed! ...Read more

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If I have a hemi thyroidectomy for nontoxic multinodular goiter, the other lobe that is already mild enlarged will grow faster and forms nodules?

Goiter: Yes, the other side of your thyroid may grow. If your doctor treats you with levothyroxine, it may not grow as much, but there is a risk of making you hyperthyroid. It sounds like the remaining lobe also has nodules. Presumably the removed thyroid was free of cancer; why was the surgery performed? You probably should see an endocrinologist. ...Read more

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I had total thyroidectomy due to huge multinodular goiter with compression 1 week ago. Is a 1.5" diameter X 3" long swelling needing narcotics typical?

Post-op pain: This really depends on how the surgery went. Opioids for post-op pain is fine, it has been 1.5 weeks so the need for the opioid should have reduced as you should be healing quite well. ...Read more

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My tt report 1-hutrhel adenoma of right lobe with multinodular goiter, focal hyperplastic, involutional change 2-no malignancy seen is it bad? Tg is. 8

My tt report 1-hutrhel adenoma of right lobe with multinodular goiter, focal hyperplastic, involutional change 2-no malignancy seen is it bad? Tg is. 8

No: It's good. I'm betting it's a benign nodule. If it keeps growing, have it checked again, or if it bugs you or you don't like the way it looks, it can come out. ...Read more

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Test results are multinodular goiter so radionuclide thyroid scan?

Need more info: Not sure what you mean by "test results" but u cannot know that u have multinodular goiter from a blood test. A thyroid ultrasound can give u this diagnosis in which case u will need a blood test called TSH to know what to do next. No thyroid scan needed unless the TSH is low. Thyroid ultrasound vs. Biopsy might be needed depends on the size and characteristics of the nodules but need more info. ...Read more

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I have multinodular goiter with more involvement on the right side. Two biggest nodules are 1.5 cm. Could thiscause some difficulty swallowing?

Unlikely: 1.5 cm nodules often are not big enough to cause compressive symptoms. I would look into another diagnosis, like acid reflux. A good ENT visit will be worthwhile. Also make sure that nodules is followed up on. Gold standard is us guided biopsy. ...Read more

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I recently was diagnosed with a 2.2 CM multinodular goiter on the right lobe of my thyroid. Does thyroid affect the immune system?

Generally not: Not unless it's not functioning properly, which is different that it it has a nodule. If the nodule itself is 2.2 cm, then it needs to be biopsied. ...Read more

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Thyroid sono results:"heterogeneous gland suggesting multinodular goiter -no discrete dominant masses observed"-what does this mean?

Thyroid sono results:"heterogeneous gland suggesting multinodular goiter -no discrete dominant masses observed"-what does this mean?

Lumpy!: Opinions vary, but... Especially for women, thyroid nodules are very common. These are sometimes familial or inherited and are sometimes more common later in life. There is little to worry about, especially without a specific "dominant" nodule over ~1cm. You should get thyroid blood work and a followup ultrasound within a few months. If the gland is huge, you may need treatment. ...Read more

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Recently was diagnosed with a 2.2 CM multinodular goiter on the right lobe of my thyroid. Does your thyroid affect the immune system?

Recently was diagnosed with a 2.2 CM multinodular goiter on the right lobe of my thyroid. Does your thyroid affect the immune system?

Autoimmune diseases: A goiter does not make you more susceptible to infections, if that is your question. But a common cause of goiter is hashimoto's thyroiditis, which is an autoimmune dysfunction of your thyroid. In most people with hashimotos, only the thyroid is affected. ...Read more

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I have a Multinodular goiter with 7 nodules, largest 2 on isthmus at 2.1 & 2.7 cm. Could these cause breathing, swallowing & voice issues when I eat?

I have a Multinodular goiter with 7 nodules, largest 2 on isthmus at 2.1 & 2.7 cm. Could these cause breathing, swallowing & voice issues when I eat?

Anatomical: Yes, these potentially could cause some issues with pressing inwards and giving feeling of pressure, and swallowing, voice issues. Your ultrasounds and exam would help delineate this more clearly though! ...Read more

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Why do the nodules of a multinodular goiter not show up on a i-123 thyroid uptake scan?

Why do the nodules of a multinodular goiter not show up on a i-123 thyroid uptake scan?

Scan shows activity: A thyroid scan looks for functioning thyroid tissue. Much of a multinodular goiter can be nonfunctional and thus not show up well or will blend into the background thyroid tissue. ...Read more

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How often should a thyroid sonogram be repeated? Sono done 1 year ago showed heterogeneous multinodular goiter.

How often should a thyroid sonogram be repeated? Sono done 1 year ago showed heterogeneous multinodular goiter.

It depends: Upon a variety of factors, such as clinical changes, palpation by physician, prior ultrasound and lab findings, biopsy findings (if biopsy was done), personal and family history etc. Check w/your physician who should be able to tell you. Brand name T4 replacement is more reliable than your generic. ...Read more

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I have multinodular goiter with two nodules measuring 10 mm and 11 mm on each lobe, then there are scattered ones throughout my thyroid. Biopsy?

Depends: The decision to biopsy is made between you and your treating physician. It depends on your level of comfort, what it looks like on ultrasound and whether or not it had changed from previous ultrasounds. Your choice right now is to undergo biopsy or do another ultrasound in 1 year and biopsy only if changes are seen. Both choices are reasonable. ...Read more