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Doctor insights on: Why Might Ldh Be Elevated In B12 Deficiency

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Why might ldh be elevated in B12 deficiency?

Why might ldh be elevated in B12 deficiency?

RBC breakdown: Ldh enzyme (subtype 4h) is very abundant in red blood cells and heart muscle. In vit B12 deficiency there is high destruction of red cells in the bone marrow and in the blood vessels. As rbcs ruptures they release their inner content into the blood stream and this causing elevation of ldh levels in the bloodstream. ...Read more

Dr. Mohammed Parvez
243 Doctors shared insights

Vitamin B12 Deficiency (Definition)

Occurs when there is a lack of absorption or intake from diet. Symptoms can ...Read more


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In B12 deficiency, if autoantibodies are within normal range could it be thst they were elevated in the past? Thank you in advance

In B12 deficiency, if autoantibodies are within normal range could it be thst they were elevated in the past? Thank you in advance

Malabsorption: There are many other possible causes for B12 deficiency besides autoimmunity: any cause of malabsorption anywhere in the digestive tract from the stomach to the large intestine can eventually cause B12 deficiency. If you are proven deficient, get regular B12 injections. ...Read more

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What does B12 deficiency cause?

Anemia: The most common complication of B12 deficiency is anemia. Pernicious anemia, which is an autoimmune process that can cause profound B12 deficiency, is associated also with neurologic symptoms such as weakness/numbness/tingling, memory problems, personality changes. The tongue can become shiny and sore. Symptoms respond to vitamin B12 supplementation, frequently injections if pernicious anemia. ...Read more

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How do I improve my B12 deficiency?

How do I improve my B12 deficiency?

Monthly B12: Injections. Tablets can also supplement daily. But the source of your deficient level should be discussed with your internist. ...Read more

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B12 deficiency cause pts become aggrasive?

B12 deficiency cause pts become aggrasive?

May be: Vit B12 plays important role in normal functioning of brain and nervous system. Deficiency is known to cause cognitive impairment and behavior disturbances in elderly. ...Read more

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What to do if I have B12 deficiency is this bad?

What to do if I have B12 deficiency is this bad?

Pernicious Anemia: Vitamin B12 is crucial for the formation of red blood cells, as well as the good functioning and health of nerve tissue. A definciency in this vitamin can lead to anemia and the associated symptoms of fatigue, aches, malaise, etc. It is often treatable with replacement of the vit b-12 and laboratory monitoring. Best wishes. ...Read more

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What to expect if my current state of B12 deficiency persists?

B12 injections: B 12 deficiency can be easily treated with injections of b12. Once a month is more than enough, less frequent may be adequate, but at least twice a year. If you get treatment, you should not have issues from B12 deficiency, though the reason for why you have deficiency should also be addressed. ...Read more

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Should strenuos exercise be avoided if one has B12 deficiency?

Not necessarily: First of all, its not too difficult to up your B12 even if you are a vegan, you can take it sublingually. Second, I think the bigger problem is the paresthesias, and pain. Those will inhibit exercise more than the B12 deficiency. ...Read more

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What to do if I have B12 deficiency, this is not that bad is it?

Pernicious anemia: Vitamin B12 is crucial for the formation of red blood cells, as well as the good functioning and health of nerve tissue. A definciency in this vitamin can lead to anemia and the associated symptoms of fatigue, aches, malaise, etc. It is often treatable with replacement of the vit b-12 and laboratory monitoring. Best wishes. ...Read more

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Help! Can B12 deficiency run in families?

Help! Can B12 deficiency run in families?

Possible: The B12 deficiency from lack of the cofactor for absorption from the stomach could "run in families". ...Read more

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Could hemochromatosis cause B12 deficiency?

Could hemochromatosis cause B12 deficiency?

Possibly indirectly: The principle treatment for iron overload due to hereditary hemochromatosis is phlebotomy--removing blood/red blood cells. Other important nutrients such as B12 and folic acid are also removed. Many hematologists recommend supplementing vitamins B12, B6 & folic acid to help support the blood when a patient is receiving regular phlebotomy. A daily multivitamin/mineral is a good place to start. ...Read more

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What happens to hemoglobin in B12 deficiency?

What happens to hemoglobin in B12 deficiency?

It decreases: In B12 deficiency, anemia develops, blood cells enlarge, and the hemoglobin declines. ...Read more

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What are signs and symptoms of B12 deficiency?

B12 Deficiency: B12 deficiency can lead to anemia, with symptoms of fatigue, tiredness and exercise related shortness of breath. Neurological symptoms include numbness, parasthesias (tingling of hand and feet), decreased reflexes, ataxia (difficulty walking). Psychiatric symptoms include dementia, personality changes, psychosis, and impaired memory. ...Read more

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Can a B12 deficiency cause loss of smell and taste?

Can a B12 deficiency cause loss of smell and taste?

Doubtful: Your question is very concerning. You're a diabetic, you state you are sad, and you're just reported loss of smell and taste. These need to be worked up. Is it you antidepressant medication? This is infamous. Do you have nasal polyps? Easy to fix. If you are also B12 deficient, this is extremely serious and needs to be worked up and addressed. But it's probably not the cause. ...Read more

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Is light headedness connected with vit B12 deficiency?

Is light headedness connected with vit B12 deficiency?

Yes, but...: Vitamin B12 deficiency is surprisingly common and becomes more common as we age. It can cause dozens of different symptoms including lightheadedness, but there are many other possible causes of lightheadedness, so this deserves further evaluation. See www. Webmd. Com/food-recipes/guide/vitamin-b12-deficiency-symptoms-causes. ...Read more

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How easy is it to lose weight despite a B12 deficiency?

How easy is it to lose weight despite a B12 deficiency?

B12 weight loss: An issue with b12, which is easily correctable, and the ability to lose weight have never been directly connected. ...Read more

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Is neuronal demylenation due to B12 deficiency reversible?

Partly: Good question from a med student. Vegetarian's myelopathy is all-too-familiar and it regresses at least some. Here's one of the unlucky ones: http://www. Ncbi. Nlm. Nih. Gov/pubmed/17616346 forgive me, but I can't grant any moral high ground to someone who paralyzes himself. ...Read more

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Can you have a B12 deficiency and have 'normal' serum B12 levels?

Yes: Vitamin B 12 is used inside the cell and is the reason why measuring vitamins in the blood does not give you an answer that is practical. ...Read more

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B12 deficiency. I take cobalamin. Should I be taking Methylcobalam instead?

B12 deficiency. I take cobalamin. Should I be taking Methylcobalam instead?

Methylcobalamin best: You must be taking cyanocobalamin (most common) or hydroxocobalamin. These are both effective but methylcobalamin has some significant advantages and is the optimal form to take if possible.
See http://centraldrugsrx. Com/doctorblog/comments/brief-comparison-of-the-three-formulations-of-vitamin-b12
and http://drfairchild. Blogspot. Com/2012/12/b12-deficiency. Html for more information. ...Read more

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Are there other labwork findings for B12 deficiency other than the serum level itself?

Yes: The CBC is the first test done. In patients with borderline serum levels or symptomatic patients with normal levels, Homocysteine and Methylmalonic Acid test can be used to exclude this diagnosis or confirm it. ...Read more

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I have a B12 low of 236 symptoms of B12 deficiency and a ferritin of 44. Could this be B12 deficiency?

I have a B12 low of 236 symptoms of B12 deficiency and a ferritin of 44. Could this be B12 deficiency?

B12: Your B12 is low. And ferritin is low. You require evaluation as to why for each, but particularly B12, and B12 injections. You may not absorb B12 well in your intestine. ...Read more

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What meds are available for B12 deficiency? What are side affect of each? (injectible meds my B12 levels were 169). Thanks

What meds are available for B12 deficiency? What are side affect of each? (injectible meds my B12 levels were 169). Thanks

Methylcobalamin: Injectable B12 is the surest way to increase your B12 levels. Injections are usually administered weekly, but I occasionally prescribe them on a daily basis. Methylcobalamin is the most bio-available form of b12, but is slightly more expensive than the traditional cyancobalamin form. Sublingual methylcobalamin is the next most effective way to restore tissue B12 levels. No adverse effects. ...Read more

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B12 deficiency and receiving injections for the past two years yet my levels have not come up past 190 would there be a reason for this?

Sounds odd: How was the deficiency proved? Were there changes in blood? The quoted level is already high and may mean that the injected B12 is not being used in metabolism. I can't help any further. ...Read more

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I've had severe vit B12 deficiency but they haven't been able to find any cause for it. Been taking inject every 2nd day for years now. Dangerous?

I've had severe vit B12 deficiency but they haven't been able to find any cause for it. Been taking inject every 2nd day for years now. Dangerous?

Too frequent: Injections. Body can store enough B12 to last a person for a year. Are you injecting yourself? You do not need injections more frequently than every 3-6 months. I would recommend seeing your doctor for an evaluation and injection frequency. ...Read more

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If I eat a flexitarian diet like Okinawans, Japanese, & some Africans do will I avoid b12 deficiency like they do? Or do they have B12 deficiency?

If I eat a flexitarian diet like Okinawans, Japanese, & some Africans do will I avoid b12 deficiency like they do? Or do they have B12 deficiency?

Animal protein: I do not know what these diets are. To have adequate intake of B12 you need to consume animal protein, keeping in mind that milk is an animal protein. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco or alcohol in any form.
Practice safe sex. ...Read more

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Strongly suspect B12 deficiency. How to cure/treat it w/o dr visit? Can't afford dr. Can I just take certain amt B12 daily? How much? I'm 38, 115 lbs, 5'6.

Don't self-diagnose: If you are a vegetarian, you need to supplement or you are likely to end up with brain damage. Even the vegan leadership acknowledges this. If you have self-diagnosed B12 deficiency from some other cause, then either you are wrong (and you have symptoms from some other cause which must be discovered) or you have pernicious anemia, for which you need injections to avoid brain damage. ...Read more

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Once you have a B12 deficiency and take monthly injections, will that be the case for the rest of your life or will you be able to stop injections?

B12 deficiency: Unfortunately, you will need to take B12 lifelong. To stop would put you at risk for anemia and severe neurologic problems like neuropathy, difficulty with balance and walking, "megaloblastic madness", and death. Sometimes, patients can take high doses of vitamin B12 1-2 mg orally once daily instead of the shots. Ask your doctor if this is possible for you. ...Read more

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Are there any other conditions B12 could treat other than a B12 deficiency? Since getting shots, 95% of my neurologic and nerve-related symptoms gon

Are there any other conditions B12 could treat other than a B12 deficiency? Since getting shots, 95% of my neurologic and nerve-related symptoms gon

Not A Panacea: It will only definitely treat something that results from its deficiency, like many problems of nerves. But it is used in just about every cell in the body as a cofactor and may indirectly affect a lot of metabolic processes. It's been touted for problems from restless legs to a cream for eczema and a sublingual pill for canker sores. I'll bet they come up with a B12 enema soon. ...Read more

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Can neuropathy from a B12 deficiency be reversed?

Can neuropathy from a B12 deficiency be reversed?

Depends: This depends on the severity and length of time you have had the deficiency. If it was caught and corrected very early, then yes, it should improve. The longer you have the deficiency and the more damage done, the less likely it will improve. Nerves grow extremely slow and the repair can occur over such a long time you barely notice it happening. I how this answer helps! ...Read more

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What are B12 deficiency?

What are B12 deficiency?

Low vitamin B12: Vitamin B12 deficiency is a low blood level of vitamin b12. It can cause permanent damage to nerves if left untreated long enough. Vitamin B12 was discovered through investigation of pernicious anemia, which is an autoimmune disease that leads to inadequate intestinal absorption of B12 from foods. Symptoms may include anemia and paresthesias (from nerve damage). ...Read more

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Any tips on B12 deficiency?

Usually caused: By a problem with a stomach cofactor for absorption, so you cannot overcome the problem with oral supplements. I'm shots work fine and will correct the blood problems. Can also lead to neurologic issues so treatment is important. ...Read more

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How to know what is B12 deficiency?

Pernicious anemia: Vitamin B12 is crucial for the formation of red blood cells, as well as the good functioning and health of nerve tissue. A definciency in this vitamin can lead to anemia and the associated symptoms of fatigue, aches, malaise, etc. It is often treatable with replacement of the vit b-12 and laboratory monitoring. Best wishes. ...Read more

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What are the symptoms of B12 deficiency?

See below: Weakness and fatigue
Light-headedness and dizziness
Palpitations and rapid heartbeat
Shortness of breath
A sore tongue that has a red, beefy appearance
Nausea or poor appetite
Weight loss
Diarrhea
Yellowish tinge to the skin and eyes

Numbness and tingling in the hands and feet
dementia
memory loss
depression
muscle weakness
irritability ...Read more

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How long does it take to reverse a B12 deficiency?

As soon as you: Receive an injection of B12 the deficiency will be relieved. However it may take time for some of the effects of B12 deficiency, such as neuropathy and low blood counts to correct. ...Read more

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Is B12 B12 deficiency dangerous if you don't do anything about it?

Is B12 B12 deficiency dangerous if you don't do anything about it?

POSSIBLY: Prolonged B12 deficiency can result in peripheral neuropathy and reduced mental function. If left untreated the damage can become permanent. If pernicious anemia exists, the deficiency can be fatal. Early signs are seen in blood work where MCV and/or MCH values are elevated, which indicate a B12 and/or Folic Acid deficiency. B12 is best given im or sq. Take professional grade b-complex, too. ...Read more

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What is the recommend dosage for a 60 year old female with B12 deficiency?

What is the recommend dosage for a 60 year old female with B12 deficiency?

Inject 1mg per month: Vitamin B12 is usually given 1 milligram per month as an injection. Early in the course of treatment, the doctor may give the 1 mg (1000 micrograms) daily for some days, weekly for some weeks, and then monthly thereafter. Doctors may adjust the dosing schedule depending on a patients level of, and reason for, B12 deficiency. ...Read more

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Family is know for B12 deficiency. Would it be ok for me to take B12 without having it checked?

Family is know for B12 deficiency. Would it be ok for me to take B12 without having it checked?

B12 deficiency: You should have a vitamin/mineral analysis done first before you begin supplementing as it may be unneccessary and excessive amounts of B12 can effect b6. Best wishes. ...Read more

Dr. Randy Baker
1,013 Doctors shared insights

Vitamin B12 (Definition)

Vitamin B12 is a vitamin which is a kind of nutritional agent ...Read more