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Doctor insights on: Why Low Tsh And High T4

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My free T4 is high 19.30 pmol/l and my TSH is also high 4.530 mlu/l. What does this mean?

My free T4 is high 19.30 pmol/l and my TSH is also high 4.530 mlu/l.  What does this mean?

Few possibilities: These labs seem at odds, with TSH suggesting overactive thyroid and ft4 underactive thyroid. Free T4 tests can be inaccurate in some people who have interfering substances present. Another possibility is a tumor in the pituitary secreting too much TSH resulting in thyroid overactivity, and high thyroid hormone levels. This is quite rare, however. Your doctor can help sort this out. ...Read more

Dr. Quang Nguyen
893 doctors shared insights

Thyroid Stimulating Hormone (Definition)

A TSH test measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland and tells the thyroid gland to make and release the hormones thyroxine ...Read more


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Could a low TSH and high T4 be an indication of iodine deficiency ?

Could a low TSH and high T4 be an indication of iodine deficiency ?

Iodine deficiency: Iodine is the base for thyroid hormone. Since the T4 is high, it is unlikely that there is an iodine deficiency. It may be possible that you have a thyroid peri oxidase deficiency, which may cause a lack of t3 (liothyronine). You should consult an endocrinologist. ...Read more

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I'm concerned. I have a low TSH and high t4. I'm symptomatic of hyperthyroidism. Can't take ptu (propylthiouracil) or tapazole. What happens now?

I'm concerned. I have a low TSH and high t4. I'm symptomatic of hyperthyroidism. Can't take ptu (propylthiouracil) or tapazole. What happens now?

Diagnosis first: You may or may not have grave's disease. Your doctor needs to determine the cause of your test results before treating test results. Meanwhile, if not contraindicated, a beta blocker could be useful in terms of treating hyperthyroid symptoms. Causes of your hyperthyroidism also include: hashimoto's, subacute thyroiditis, and toxic thyroid nodule. ...Read more

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What is meant by low TSH high free t4?

What is meant by low TSH high free t4?

Hyperthyroidism: A low TSH and high T4 is an indication of over-active thyroid (hyperthyroidism). This should be evaluated further for any potential cause and discuss treatment options with your physician. Referral to an endocrinologist may be necessary. ...Read more

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Low TSH high free t4? What is the cause?

Low TSH high free t4?  What is the cause?

Hyperthyroidism: High ft4 and low TSH are a combination usually indicating an over active thyroid. It doesn't explain the cause which will require further testing to figure out. ...Read more

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Very low TSH with high normal free T4. Twitching. Changed dose. How long til levels normal out? Still twitching 2 weeks later. Had basic neuro exam.

Very low TSH with high normal free T4. Twitching. Changed dose. How long til levels normal out? Still twitching 2 weeks later. Had basic neuro exam.

What did you: change the dose of? If it's thyroid replacement, it can take weeks for the level to normalize, asumming you're now on the correct dose. If it's an ANTI-thyroid drug, it can takes months to work as it only inhibits the formation of NEW thyroid hormone, not the hormone that's already been manufactured. ...Read more

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Does low TSH mean I have a problem with my pituitary gland ? Hypopituitarism? My free T3 (liothyronine) and T4 are high normal???

Does low TSH mean I have a problem with my pituitary gland ? Hypopituitarism? My free T3 (liothyronine) and T4 are high normal???

Low TSH: May reflect Hypopituitary condition if FT4 and FT3 are low also. However if both are high that will indicate Hyperthyroidism. Discuss with your doctor about other modifers like acute illness or medication effects or pregnancy on your thyroid panel result ...Read more

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My 10yr old daughter had lab work completed and the results show a high esr, low tsh, and normal t3/t4. What are possible diagnosis?

My 10yr old daughter had lab work completed and the results show a high esr, low tsh, and normal t3/t4. What are possible diagnosis?

Possibly thyroiditis: The information is incomplete, but subacute thyroiditis (sat), an inflammation of the thyroid gland can cause hyperthyroidism and high esr. People with sat have severe neck pain. With no pain sat is unlikely. A high ESR is found in many non-thyroid conditions: one can have mild hyperthyroidism and another cause for a high esr. Some people with non-thyroid illness have low TSH without being hyper. ...Read more

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Had total thyroidectomy 10 years ago. Currently 8 weeks pregnant, taking synthroid (thyroxine) 125mcg. Very low TSH 0.01 and high free T4 at 26 (normal 12-22). ?

Way off: That dose of thyroid needs to be reduced ASAP. Please consult with your doctor right away. I'm guessing they're doing that already if they received those test results. ...Read more

Dr. David Sneid
1,375 doctors shared insights

Thyroxine (Definition)

Thyroxine is a thyroid ...Read more