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Doctor insights on: Why It Is Said That Cephalosporins Can Cause Hemolytic Anemia

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Emily Lu Dr. Lu
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Why it is said that cephalosporins can cause hemolytic anemia?

Emily Lu Dr. Lu
3 doctors agreed:
Why it is said that cephalosporins can cause hemolytic anemia?

Autoimmune reaction: Cephalosporins interact with red blood cell membranes. The body can sometimes produce antibodies against cephalosporins that also interact with the surface of red blood cells. These antibodies thus activate the body's immune system to attack its own red blood cells, causing hemolytic anemia. This is a rare but severe side effect of cephalosporins. ...Read more

Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


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Can zinadol(cefuroxime) induce hemolytic anemia to g6pd patients? There is a risk of hemolysis with cephalosporins, is it greater for g6pd patients?

Can zinadol(cefuroxime) induce hemolytic anemia to g6pd patients?

There is a risk of hemolysis with cephalosporins, is it greater for g6pd patients?

Not likely a risk: The list of antibiotics to avoid in patients with G6PD deficiency include nitrofurans, sulfonamides and quinones (and chloramphenicol). Some of these are considered to be safe at usual doses for class II and III disease. Cephalosporins should not contribute to hemolysis. ...Read more

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I was diagnosed with hemolytic anemia caused by malaria. Can it be cured?

I was diagnosed with hemolytic anemia caused by malaria.  Can it be cured?

Yes: Malaria symptoms show up a week to a few months after being infected by a mosquito bite. With treatment, the symptoms should go away in a couple of weeks. However, without treatment, and depending on the strain of malaria parasite, an infected person can have symptoms for a few years, up to a few decades. The person develops immunity over time, and his symptoms may decrease as the years go by. ...Read more

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Feels dizzy back of head. Example; sharp turn as passenger in car can cause feeling and can last hours. Worse lying down. Has minor Hemolytic anemia?

Feels dizzy back of head. Example; sharp turn as passenger in car can cause feeling and can last hours. Worse lying down. Has minor Hemolytic anemia?

BPPV?: Maybe benign paroxysmal postural vertigo. BPPV is very common, occuring sometimes in up to 5% of the population. It's most frequent in older persons but can occur at any age. Just as certain positions or movements can trigger it, positional procedures usually can reverse it quickly. Unrelated to anemia, hemolytic or other. Google BPPV for lots of websites; the Wikipedia article is pretty good. ...Read more

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Can hemolytic anemia cause low blood vol. Thereby causing autonomic dysfunction? Does body see hemolysis as trauma thereby triggering stress hormones?

Can hemolytic anemia cause low blood vol. Thereby causing autonomic dysfunction? Does body see hemolysis as trauma thereby triggering stress hormones?

Whoa: Hemolytic anemia won't affect blood volume but will affect oxygen carrying capacity. Further, if the cause is microangiopathy, lupus, malaria, or any of a variety of others, there may be a huge number of different problems. I'm glad you have an inquiring mind, but there's no need to invoke "stress hormones"; you'd do well to stop reading "pop" explanations if someone's actually seriously sick. ...Read more

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Can hemolytic anemia be treated?

Yes: Hemolytic anemia can be due to multiple causes such as medications, infections, cancers, autoimmune disorders, etc. Depending on the cause treatments can be done such as stopping causative drugs, treating infections or cancers, starting folic acid, sometimes transfusing blood, etc. ...Read more

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